ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Metabolism >Factor Xa inhibitor >Edoxaban (tosylate Monohydrate)

Edoxaban (tosylate Monohydrate)

CAS No.: 1229194-11-9

Chemical Name:: Edoxaban (tosylate Monohydrate)

Synonyms: Edoxaban tosilate;edoxaban tosylate hydrate;Edoxaban Tosilate Monohydrate;Lixiana;Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate, hydrate;CS-1597;Yidu Saban Mesylate;Edoxaban Tosylate Hydrate 1;Etuxaban p-toluenesulfonate;Edoxaban (TsOH salt hydrate)

CBNumber:: CB82645582

Molecular Formula:: C31H38ClN7O7S2

Molecular Weight:: 720.26

MOL File:: 1229194-11-9.mol

MSDS File:: SDS

Modify Date:: 2024/7/3 13:03:20

Request For Quotation

Edoxaban (tosylate Monohydrate) Properties

Melting point	>252°C (dec.)
storage temp.	Hygroscopic, Refrigerator, under inert atmosphere
solubility	Chloroform (Very Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)
form	Solid
color	White to Off-White
Stability	Hygroscopic
InChIKey	ZLFZITWZOYXXAW-BUZWFPPCNA-N
SMILES	S(C1C=CC(C)=CC=1)(O)(=O)=O.N([C@@H]1C[C@@H](C(=O)N(C)C)CC[C@@H]1NC(=O)C(=O)NC1N=CC(Cl)=CC=1)C(C1SC2CN(C)CCC=2N=1)=O \|&1:12,14,22,r\|

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

Edoxaban (tosylate Monohydrate) Chemical Properties,Uses,Production

Uses

Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor.

Definition

ChEBI: A hydrate that is the monohydrate of the tosylate salt of edoxaban. Used for the treatment of deep vein thrombosis and pulmonary embolism.

Clinical Use

Daichi Sankyo’s edoxaban tosilate is an orally administered coagulation factor Xa inhibitor that was approved and launched in Japan for the preventive treatment of venous thromboembolic events (VTE) in patients undergoing total knee arthroplasty, total hip arthroplasty, or hip fracture surgery. Edoxaban has been shown to have a rapid onset of anticoagulant effect due to short Tmax (1–2 h) after dosing and sustained for up to 24 h post-dose. Marketed under the brand name Lixiana, it is currently in phase III studies in the US for the prevention of stroke and systemic embolic events in patients with atrial fibrillation (AF) and venous thromboembolism (VTE).

Edoxaban (tosylate Monohydrate) Preparation Products And Raw materials

Raw materials

Preparation Products

Edoxaban (tosylate Monohydrate) Suppliers

Global( 250)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Mehta API Pvt. Ltd.	+91-9920552082 +91-9920552082	Maharashtra, India	33	58	Inquiry
CVR Life sciences Pvt Ltd	+91-7386789224 +91-9912960099	Hyderabad, India	22	58	Inquiry
Metrochem API Private Limited	+91-4069069999 +91-4069069999	Telangana, India	78	58	Inquiry
Honour Lab Limited	+919845977466	Telangana, India	164	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
CADILA HEALTHCARE LTD	+91 2718 225001	New Delhi, India	110	58	Inquiry
HONOUR LAB LTD	+91-40-23710405	New Delhi, India	39	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry

Supplier	Advantage
Mehta API Pvt. Ltd.	58
CVR Life sciences Pvt Ltd	58
Metrochem API Private Limited	58
Honour Lab Limited	58
Pharma Affiliates	58
CADILA HEALTHCARE LTD	58
HONOUR LAB LTD	58
A.J Chemicals	58
CLEARSYNTH LABS LTD.	58
SynZeal Research Pvt Ltd	58

Edoxaban (tosylate Monohydrate) Spectrum

Edoxaban (tosylate Monohydrate)(1229194-11-9)¹HNMR

1229194-11-9(Edoxaban (tosylate Monohydrate))Related Search:

(1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl Methanesulfonate EthanediaMide, N1-(5-chlo... Thiazolo[5,4-c]pyridine, 4,5,6,7-tetrahydro-5-methyl- Tert-Butyl(1R,2S,5S)-2-azido-5-[(dimethylamino)carbonyl]cyclohexylcarbamate oxalic acid Edoxaban (TsOH salt)

Edoxaban Edoxaban Impurity 12 (1R,2R,4S) EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- EthanediaMide, N1-(5-chlo... Edoxaban-d6

Edoxaban Impurity 16 (1S,3S,4S)-3-AMino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2S,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- (1S,3R,4S)-4-(2-((5-chloropyridin- 2-yl)amino)-2-oxoacetamido)-3-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexane-1-carboxylic acid (1R,3R,4R)-3-AMino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester

2-Amino-5-chloropyridine Everolimus Bortezomib

chevron_left

1of4

chevron_right

Edoxaban (tosylate Monohydrate) Edoxaban p-toluenesulfonate monohydrate N-(5-Chloropyridin-2-yl)-N'-((1S,2R,4S)-4-[(dimethyl amino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl)ethanediamide p-toluenesulfonate monohydrate N1-(5-Chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide 4-methylbenzenesulfonate hydrate Edoxaban Tosylate Hydrate 1 Edoxaban (TsOH salt hydrate) CS-1597 Edoxaban tosylate monohydrate(for Edoxaban) DU-176b tosylate Monohydrate Edoxaban (tosylate Monohydrate) USP/EP/BP Edoxaban tosylate monohydrate (DU-176b) Edoxaban tosilate Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonate, hydrate edoxaban tosylate hydrate Edoxaban Tosilate Monohydrate Lixiana Idoseban p-Toluenesulfonate Monohydrate Edoxaban Impurity 34 p-Toluenesulfonate Salt Monohydrate Edoxaban Impurity 29 p-Toluenesulfonate Salt Etuxaban p-toluenesulfonate Yidu Saban Mesylate 1229194-11-9 C24H30ClN7O4SC7H8O3SH2O C31H40ClN7O8S2 Inhibitors API