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ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile

5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile

5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile Structure
CAS No.
1240948-77-9
Chemical Name:
5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile
Synonyms
Vonoprazan-4;Vonoprazan-027;TAK438 Impurity 19;VonoprazanImpurity74;Vonolazan impurity 4;Vonoprazan Impuirty 64;Vonoprazan Impurity 06;Vonoprazan Fumarate impurity B;Voronozan initiator 1 impurity J;Vonoprazan impurity SM2-I: 3-nitrile
CBNumber:
CB82660381
Molecular Formula:
C11H7FN2
Molecular Weight:
186.19
MOL File:
1240948-77-9.mol
MSDS File:
SDS
Modify Date:
2024/3/26 15:02:14
Request For Quotation

5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile Properties

Boiling point 364.7±32.0 °C(Predicted)
Density 1.28±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 13.87±0.50(Predicted)
form Solid
Dielectric constant 5.5（22.0℃）
InChI InChI=1S/C11H7FN2/c12-10-4-2-1-3-9(10)11-5-8(6-13)7-14-11/h1-5,7,14H
InChIKey ZDEFHFJZEDEKJO-UHFFFAOYSA-N
SMILES N1C(C2=CC=CC=C2F)=CC(C#N)=C1

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
HS Code  2933998090

5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile Chemical Properties,Uses,Production

Description

5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile is an important pharmaceutical intermediate component for the preparation of vonorasan fumarate, vonoprazan key intermediate, and vorexanol fumarate intermediate.

Uses

5-(2-Fluorophenyl)-1H-pyrrole-3-carbonitrile is an impurity of Vonoprazan (V767010) a novel potassium-competitive acid blocker for the treatment of acid-related diseases.

5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile Preparation Products And Raw materials

Raw materials

2'-Fluoroacetophenone 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile 2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile 2-Bromo-2'-fluoroacetophenone

Preparation Products

5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde

5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile Suppliers

Global( 241)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Stereokem Pvt Ltd +91-4029706929 +91-9394224843 Telangana, India 350 58 Inquiry
VGS SYNTHESIS PRIVATE LIMITED +91-9866975588 +91-9866975588 Hyderabad, India 1818 58 Inquiry
Mekanar Pharma Private Limited +91-9154988357 +91-9948050784 Hyderabad, India 27 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD +86-576-88902229;+86-0576-88902229 +8613968687450 China 158 58 Inquiry
JUYE XIANDAI fine chemistry Co.,Ltd +86-18958038633; +8618958038633 China 64 58 Inquiry
Hebei Yanxi Chemical Co., Ltd. +86-17531190177; +8617531190177 China 5873 58 Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd +86-0533-2185556 +8617865335152 China 10978 58 Inquiry
Hebei Xinsheng New Material Technology Co., LTD. +86-16632316109 China 1090 58 Inquiry
Supplier Advantage
Stereokem Pvt Ltd 58
VGS SYNTHESIS PRIVATE LIMITED 58
Mekanar Pharma Private Limited 58
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD 58
JUYE XIANDAI fine chemistry Co.,Ltd 58
Hebei Yanxi Chemical Co., Ltd. 58
Zibo Hangyu Biotechnology Development Co., Ltd 58
Hebei Xinsheng New Material Technology Co., LTD. 58

1240948-77-9(5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile)Related Search:

2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile 3-Pyridinesulfonic acid 2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile 5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde 3-N,N-dimethylsulfamoylpyridine
(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl) methanol 1H-Pyrrole-3-carboxylic acid, 5-(2-fluorophenyl)-, ethyl ester 5-(4-fluorophenyl)-1H-pyrrole-3-carbonitrile 1H-PYRROLE-3-METHANOL, 5-(2-FLUOROPHENYL)- PYRIDINE-2-SULFONIC ACID
1-(5-(2-fluorophenyl)-1-(pyridin-2-ylsulfonyl)-1H-pyrrol-3-yl)-N- methylmethanamine fumarate (Z)-N-((5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methylene)methanamine oxide 1-methylpyridin-1-ium-4-sulfonate 4-Pyridinesulphonic acid pyridine-3-sulfonyl chloride
1H-Pyrrole-3-carbonitrile,5-(2-fluorophenyl)-1-(3-pyridinylsulfonyl)- 5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde 5-chloropyridine-3-sulfonyl chloride
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5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile TAK-438( Vonoprazan fumarate) intermediate 2 1H-Pyrrole-3-carbonitrile,5-(2-fluorophenyl)- Vonoprazan Fumarate impurity B TAK438 Impurity 19 Vonoprazan impurity 32/5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile Vonoprazan impurity SM2-I: 3-nitrile Vonoprazan-4 Vonoprazan Impuirty 64 Voronazan Fumarate Starter 1 Impurity J Voronozan initiator 1 impurity J Vonoprazan-027 6,6-dimethyl-2-ene-4-alkyne chloroheptane 5-(2-Fluorophenyl)-1H-pyrrole-3-carbonitrile (Vonoprazan Impurity) VonoprazanImpurity74 Vonolazan impurity 4 Vonoprazan Impurity 06 1240948-77-9 1240948-77-4 1240948-77-8 1240948-77-9