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ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >FMoc-α-Me-Lys(Boc)-OH

FMoc-α-Me-Lys(Boc)-OH

FMoc-α-Me-Lys(Boc)-OH Structure
CAS No.
1202003-49-3
Chemical Name:
FMoc-α-Me-Lys(Boc)-OH
Synonyms
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)-2-methylhexanoic acid;Fmoc-a-Me-Lys(Boc)-OH;Fmoc-α-Me-Lys(Boc)-OH;Fmoc-alpha-Me-Lys(Boc)-OH;Fmoc-α-methyl-L-Lysine(Boc);Fmoc-alpha-Me-L-Lys(Boc)-OH;FMoc-α-Me-Lys(Boc)-OH USP/EP/BP;N6-Boc-N2-Fmoc-alfa-Me--L-Lys-OH;N6-Boc-N2-Fmoc-2-methyl-L-Lysine;(S)-Na-Fmoc-NW-Boc-α-Methyllysine
CBNumber:
CB82729321
Molecular Formula:
C27H34N2O6
Molecular Weight:
482.57
MOL File:
1202003-49-3.mol
Modify Date:
2023/4/27 16:27:43
Request For Quotation

FMoc-α-Me-Lys(Boc)-OH Properties

Boiling point 687.9±55.0 °C(Predicted)
Density 1.196±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 3.92±0.41(Predicted)
form powder
color white
InChIKey MYQXEVZHWDILHG-MHZLTWQESA-N
SMILES C(O)(=O)[C@](C)(CCCCNC(OC(C)(C)C)=O)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335-H336-H351-H373
Precautionary statements  P261-P281-P305+P351+P338
Hazard Codes  Xn
Risk Statements  36/37/38-40-67
Safety Statements  23-24/25-36/37
TSCA  No

FMoc-α-Me-Lys(Boc)-OH Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder.

Synthesis

Benzyl (2R,3S)-(?)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate (4) was successively alkylated with methyl iodide and 1,4-diiodobutane using a base. In each alkylation step anti-alkylated product formed exclusively. The iodo group was displaced with azide, which served as a precursor for the side-chain amino function. Catalytic hydrogenation with concomitant cleavage of the chiral auxiliary afforded (L)-α-Me-Lys-OH (9) in a total of four steps in good yield. (L)-Fmoc-α-Me-Lys(Boc)-OH (16) was obtained from 9 via regioselective benzyloxycarbonylation. Alternately, (L)-Fmoc-α-Me-Lys(Boc)-OH (16) was obtained via Staudinger reduction of azide (8) in a total of six steps in good yield.

FMoc-α-Me-Lys(Boc)-OH Preparation Products And Raw materials

Raw materials

L-Lysine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-methyl-, hydrochloride (1:1) Propanedioic acid, 2-[4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)butyl]-2-methyl-, 1,3-diethyl ester H-α-Me-Lys(Boc)-OH (2S)-6-amino-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylhexanoic acid Di-tert-butyl dicarbonate
N-(9-Fluorenylmethoxycarbonyloxy)succinimide
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Preparation Products

FMoc-α-Me-Lys(Boc)-OH Suppliers

Global( 97)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Apeloa Pharmaceutical Co., Ltd. +86-0571-87635730 +8615858229168 China 1478 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19915 58 Inquiry
Jiangxi Chiyan Biopharmaceutical Technology Co.,Ltd. +86-18616643091 +86-18616643091 China 246 58 Inquiry
Alpha Biopharmaceuticals Co., Ltd +86-15542445688 China 888 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Zhejiang ZETian Fine Chemicals Co. LTD +8618957127338 China 2141 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 26165 58 Inquiry
BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
Supplier Advantage
A.J Chemicals 58
Apeloa Pharmaceutical Co., Ltd. 58
Nextpeptide Inc 58
Jiangxi Chiyan Biopharmaceutical Technology Co.,Ltd. 58
Alpha Biopharmaceuticals Co., Ltd 58
Capot Chemical Co.,Ltd. 60
Zhejiang ZETian Fine Chemicals Co. LTD 58
Career Henan Chemica Co 58
Dideu Industries Group Limited 58
BOC Sciences 58

1202003-49-3(FMoc-α-Me-Lys(Boc)-OH)Related Search:

Fmoc-α-Me-L-Dab(Boc)-OH Fmoc-α-Me-homoPhe-OH FMoc-α-Me-Trp(Boc)-OH (R)-N-FMoc-2-(6'-heptenyl)alanine (S)-N-FMoc-2-(2'--propynyl)alanine
(S)-N-Fmoc-2-(3'-butenyl)alanine FMoc-α-Me-D-Pro-OH FMoc-α-Me-Asp(OtBu)-OH (S)-N-FMoc-2-(5'-pentenyl)alanine (S)-N-FMoc-2-(6'-heptenyl)alanine
(S)-N-Fmoc-2-(2'-propylenyl)alanine FMoc-α-Me-D-Phe(2-F)-OH FMoc-α-Me-D-Orn(Boc)-OH Fmoc-α-methyl-L-Leucine FMOC-ALPHA-METHYL-L-PHE
FMoc-α-Me-D-Lys(Boc)-OH FMoc-α-Me-Orn(Boc)-OH Fmoc-alpha-methyl-D-leucine
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N6-[(1,1-Dimethylethoxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-methyl-L-lysine (S)-N-ALPHA-FMOC-N-EPSILON-BOC-ALPHA-METHYLLYSINE (S)-NΑ-FMOC-NΩ-BOC-Α-METHYLLYSINE (S)-Na-Fmoc-NW-Boc-α-Methyllysine Fmoc-alpha-Me-L-Lys(Boc)-OH (2S)-6-{[(tert-butoxy)carbonyl]amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylhexanoic acid (9H-Fluoren-9-yl)MethOxy]Carbonyl Alpha-Methyl-Lys(Boc)-OH N6-Boc-N2-Fmoc-alfa-Me--L-Lys-OH (S)-N-ALPHA-FMOC-N-EPSILON-BOC-ALPHA-METHYLLYSINE, >97% Fmoc-a-Me-Lys(Boc)-OH Fmoc-α-methyl-L-Lysine(Boc) (S)-Na-Fmoc-Nw-Boc-A-Methyllysine Fmoc-alpha-Me-Lys(Boc)-OH L-Lysine, N6-[(1,1-dimethylethoxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-methyl- N6-Boc-N2-Fmoc-2-methyl-L-Lysine Fmoc-α-Me-Lys(Boc)-OH FMoc-α-Me-Lys(Boc)-OH USP/EP/BP N-α-(9-Fluorenylmethoxycarbonyl)-N-ε-(t-butoxycarbonyl)-α-methyl-L-lysine (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)-2-methylhexanoic acid (S)-Na-Fmoc-NW-Boc-α-Methyllysine 1202003-49-3 1202003-41-3 α-Methyl Amino Acids