NCX 116

NCX 116 Structure
CAS No.
860005-21-6
Chemical Name:
NCX 116
Synonyms
NCX 116;PF-3187207;Latanoprostene API;Latanoprostene bunod;Latanoprostene (PF-3187207);Inhibitor,Latanoprostene bunod,NCX 116,inhibit,NCX-116;(Z)-4-(nitrooxy)butyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoate;4-(nitrooxy)butyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2- ((R)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5- enoate;(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic acid 4-(nitrooxy)butyl ester;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-, 4-(nitrooxy)butyl ester, (5Z)-
CBNumber:
CB83070709
Molecular Formula:
C27H41NO8
Molecular Weight:
507.62
MOL File:
860005-21-6.mol
MSDS File:
SDS
Modify Date:
2023/9/20 16:43:00

NCX 116 Properties

Boiling point 658.3±55.0 °C(Predicted)
Density 1.178±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -86°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka 14.84±0.70(Predicted)
form Oil
color Colourless to Light Yellow
Stability Hygroscopic, Temperature Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H361
Precautionary statements  P201-P202-P281-P308+P313-P405-P501

NCX 116 Chemical Properties,Uses,Production

Uses

Latanoprostene Bunod is a derivative of Latanoprost and is used in the treatment of interocular pressure.

NCX 116 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 61)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Aptus Therapeutics +91-9966349855 +91-9966349855 Telangana, India 19 58 Inquiry
CHEMAZON LABORATORIES +91 9848551964 Hyderabad, India 1320 58 Inquiry
Century Pharmaceuticals Ltd +91-2652361581 +91-2652361581 Gujarat, India 53 58 Inquiry
Aspen Biopharma Labs Pvt Ltd +91-9248058660 +91-9248058662 Telangana, India 234 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
MSN LABORATORIES PRIVATE LTD +91 40 30438600 New Delhi, India 230 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21669 55 Inquiry

NCX 116 Spectrum

(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic acid 4-(nitrooxy)butyl ester Latanoprostene bunod NCX 116 PF-3187207 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-, 4-(nitrooxy)butyl ester, (5Z)- (Z)-4-(nitrooxy)butyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoate Latanoprostene API Latanoprostene (PF-3187207) Inhibitor,Latanoprostene bunod,NCX 116,inhibit,NCX-116 4-(nitrooxy)butyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2- ((R)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5- enoate 860005-21-6