Dihydrodiol Ibrutinib

CAS No.: 1654820-87-7

Chemical Name:: Dihydrodiol Ibrutinib

Synonyms: Ibrutinib Impurity 48;1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one;Dihydrodiol Ibrutinib;Ibrutinib iMpurity EQD;Ibrutinib Dihydrodiol R-Isomer;Ibrutinib Impurity 10(PCI-45227);Dihydrodiol Ibrutinib, PCI-45227;Ibrutinib Impurity 3 (PCI-45227) (Mixture ofDiastereomers);1-Propanone, 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2,3-dihydroxy-;1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one? (Ibrutinib Impurity）

CBNumber:: CB83118908

Molecular Formula:: C25H26N6O4

Molecular Weight:: 474.51

MOL File:: 1654820-87-7.mol

Modify Date:: 2023/7/14 17:30:02

Request For Quotation

Dihydrodiol Ibrutinib Properties

Melting point	>93°C (dec.)
Boiling point	790.3±60.0 °C(Predicted)
Density	1.46±0.1 g/cm3(Predicted)
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka	13.13±0.20(Predicted)
form	Solid
color	White to Off-White
Stability	Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

NFPA 704

	0
2		0

Dihydrodiol Ibrutinib Chemical Properties,Uses,Production

Uses

Dihydrodiol Ibrutinib is a metabolite of Ibrutinib (I124970). Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.

Dihydrodiol Ibrutinib Preparation Products And Raw materials

Raw materials

Preparation Products

Dihydrodiol Ibrutinib Suppliers

Global( 46)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
China National Standard Pharmaceutical Corporation Limited	+8615391658522	China	11927	58	Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	China	11027	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
Nantong Hanfang Biotechnology Co. , Ltd.	18616537568	China	30968	58	Inquiry
SHANGHAI ZZBIO CO., LTD.	19921389125 19921389125	China	12065	58	Inquiry
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD	0755-0755-0755-83725350 13380397412	China	9971	58	Inquiry
Tan-Mo Technology Co., Ltd.	19850211281	China	1980	58	Inquiry
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	China	9287	58	Inquiry
Cayman Chemical Company	(800) 364-9897	United States	6618	81	Inquiry

Supplier	Advantage
SynZeal Research Pvt Ltd	58
China National Standard Pharmaceutical Corporation Limited	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
Aladdin Scientific	58
Nantong Hanfang Biotechnology Co. , Ltd.	58
SHANGHAI ZZBIO CO., LTD.	58
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD	58
Tan-Mo Technology Co., Ltd.	58
Nanjing Shizhou Biology Technology Co.,Ltd	58
Cayman Chemical Company	81

1654820-87-7(Dihydrodiol Ibrutinib)Related Search:

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Ibrutinib 3-(2,4-dimethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)-Benzenamine 3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)benzenaMine 1,3-bis((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidin-1-yl)propan-1-one 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine

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Dihydrodiol Ibrutinib Ibrutinib iMpurity EQD 1-Propanone, 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2,3-dihydroxy- Ibrutinib Impurity 3 (PCI-45227) (Mixture ofDiastereomers) Ibrutinib Dihydrodiol R-Isomer Dihydrodiol Ibrutinib, PCI-45227 Ibrutinib Impurity 48 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one Ibrutinib Impurity 10(PCI-45227) 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one? (Ibrutinib Impurity） 1654820-87-7