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ChemicalBook > Product Catalog >Pharmaceutical intermediates >Bulk Drug Intermediates >3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Structure
CAS No.
1022150-12-4
Chemical Name:
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine
Synonyms
(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine;ibrutinib N-1;3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride;Ilutinib impurity 18;Ibrutinib Impurity 18;4-d]pyriMidin-4-ylaMine;Ibrutinib intermediate 1;Ibrutinib intermeidate N-1;Btk inhibitor 1 (R enantioMer)
CBNumber:
CB52623905
Molecular Formula:
C22H22N6O
Molecular Weight:
386.45
MOL File:
1022150-12-4.mol
MSDS File:
SDS
Modify Date:
2024/4/29 14:28:21
Request For Quotation

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Properties

Melting point 133-136oC
Boiling point 626.3±55.0 °C(Predicted)
Density 1.39±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility DMSO (Slightly), Methanol (Slightly)
pka 9.00±0.10(Predicted)
form Solid
color White to Pale Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Chemical Properties,Uses,Production

Uses

(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is an intermediate used to prepare pyrazolo-pyrimidine compounds as inhibitors of Bruton''s tyrosine kinase. It is also an intermediate for Ibrutinib (I124970) derivatives.

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Preparation Products And Raw materials

Raw materials

Preparation Products

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Suppliers

Global( 258)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Sadasivarao g +91 9515157878 Hyderabad, India 107 58 Inquiry
Bulat Pharmaceutical Pvt Ltd +91-8448085659 +91-8448085660 Haryana, India 123 58 Inquiry
Aarti Industries Limited (AIL) +91-84596144931 +91-9920899935 Maharashtra, India 235 58 Inquiry
Salvavidas Pharmaceutical Pvt., Ltd. +91-2612538898 +91-9327127459 Gujarat, India 34 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Taj Mahal Vision Chemicals Private Limited 07942557933 Mumbai, India 206 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20293 58 Inquiry
Supplier Advantage
Sadasivarao g 58
Bulat Pharmaceutical Pvt Ltd 58
Aarti Industries Limited (AIL) 58
Salvavidas Pharmaceutical Pvt., Ltd. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
SynZeal Research Pvt Ltd 58
Taj Mahal Vision Chemicals Private Limited 58
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
Henan Fengda Chemical Co., Ltd 58

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Spectrum

3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine(1022150-12-4)1HNMR

1022150-12-4(3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine)Related Search:

3-(4-Phenoxyphenyl)-1-(4-piperidinyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Btk inhibitor 1 (R enantioMer hydrochloride) Ibrutinib Impurity 21 Ibrutinib Impurity 10 Imatinib Impurity 72
(S)-Ibrutinib Chidamide (R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethanone Esmolol Impurity 2 HCl Cilastatin
10-Propargyl-10-deazaaminopterin N-Deformyl-N-pivaloyl Orlistat Ambroxol hydrochloride Clindamycin 4-Phosphate (R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-3-chloropropan-1-one
Prednicarbate 1-[(3R)-3-[4-amino-3-[4-(2,3,4,5,6-pentadeuteriophenoxy)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2,3-dihydroxypropan-1-one (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one
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3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine 3-(4-Phenoxy-phenyl)-1-(R)-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Btk inhibitor 1 (R enantioMer) Ibrutinib intermeidate N-1 3-(4-phenoxyphenyl)-1-(3-piperidyl)pyrazolo[3,4-d]pyriMidin-4-aMine 3-(4-phenoxyphenyl)-1-(3R)-3-piperidinyl-1H-Pyrazolo[3,4-d]pyrimidin-4-amine Ibrutinib (PCI-32765) Intermediates 2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-methyl-3-(4-methyl-1-piperazinyl) 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine(Btk inhibitor 1 R enantiomer) (R)-3-(4-phenoxyphenyl)-1-(piperidine-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (R)-4-Amino-3-(4-phenoxyphenyl)-1-(3-piperidyl)-1H-pyrazolo[3,4-d]pyrimidine Ibrutinib Impurity 18 (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl) (R)-3-(4-phenoxyphenyl)-1-(piperidine-3-yl)-1H-pyrazolo[3,4-d]pyrimidine-4-amine 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine 1022150-12-4 (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 1022150-12-4 3-(4-phenoxyphenyl)-1-[(3R)-piperidin-3-yl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine (R)-3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine Ibrutinib N-1 (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine (S)-Ibrutinib N-Desacryloyl Impurity (R)-3-(4-phenoxyphenyl)-1-(piperidine-3-yl)-1 H- pyrazole [3,4- d] pyrimidine-4-amine 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-phenoxyphenyl)-1-(3R)-3-piperidinyl- Ibrutinib N-Desacryloyl Impurity 3- (4-phenoxy-phenyl) -1-piperidine-3-yl-1H-pyrazolium [3, 4-D] pyrimidin-4-ylamine Ibrutinib intermediate 1 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3 4-d]pyriMidin-4-ylaMine (R)-3-(4-Phenoxyphenyl)-1 -（piperidin-3-yl）pyrazolo [3,4-D]pyrimidin-4-ylamine 3-(4-phenoxyphenyl)-1-(3-piperidyl)pyrazolo[3,4-d]pyrimidin-... (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMi TIANFUCHEM--1022150-12-4---3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine ibrutinib N-1 3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride 3-(4-phenoxypheny)1-((3R)-3-pipeidinyl)-1H-pyrazolo[3.4-dleyrimidin-4-amine Ilutinib impurity 18 (R) -3- (4-phenoxyphenyl) -1- (piperidin-3-yl) pyrazolo [3,4-D] pyrimidin-4-amine 1022150-12-4 022150-12-4 Ibrutinib Intermediates