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Neurokinin B

 Neurokinin B Structure
CAS No.
86933-75-7
Chemical Name:
Neurokinin B
Synonyms
NKB;NEUROMEDIN K;NEUROKININ K;NEUROKININ B;DMHDFFVGLM-NH2;NEUROKININ BETA;BETA-NEUROKININ;Neurokinin B NKB;Porcine neurokinin B;NKB (DMHDFFVGLM-NH2)
CBNumber:
CB8437303
Molecular Formula:
C55H79N13O14S2
Molecular Weight:
1210.42
MOL File:
86933-75-7.mol
Modify Date:
2023/9/5 11:06:04

Neurokinin B Properties

RTECS PC4360080
storage temp. -20°C
solubility Soluble to 1 mg/ml in DMSO
form Lyophilized solid.
Water Solubility Soluble to 0.80 mg/ml in sterile water
InChIKey NHXYSAFTNPANFK-KWRJECPGNA-N

SAFETY

Risk and Safety Statements

WGK Germany  3

Neurokinin B price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) N4143 Neurokinin B ≥95% (HPLC) 86933-75-7 0.5MG ₹14960.15 2022-06-14 Buy
Sigma-Aldrich(India) N4143 Neurokinin B ≥95% (HPLC) 86933-75-7 1MG ₹23176.33 2022-06-14 Buy
Sigma-Aldrich(India) N4143 Neurokinin B ≥95% (HPLC) 86933-75-7 5MG ₹98951.33 2022-06-14 Buy
Product number Packaging Price Buy
N4143 0.5MG ₹14960.15 Buy
N4143 1MG ₹23176.33 Buy
N4143 5MG ₹98951.33 Buy

Neurokinin B Chemical Properties,Uses,Production

Definition

ChEBI: Neurokinin B is a polypeptide. It is a mammalian neuropeptide of 10 amino acids that belongs to the tachykinin family is similar in structure and action to substance P and neurokinin A. It has the ability to excite neurons, dilate blood vessels, and contract smooth muscles, such as those in the urinary bladder and uterus.

Biochem/physiol Actions

Neurokinin B is a ten-residue peptide. It is an endogenous tachykinin agonist with preference for the NK-3 receptor. It is a potent bronchoconstrictor and may have a neuromodulatory role in the brain. Neurokinin B has a role in slow synaptic or non-synaptic communication.

References

[1] LAUFERR. Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalin.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1985, 82 21: 7444-7448. DOI:10.1073/pnas.82.21.7444.
[2] RANCENAOMI E. Neurokinin B and the hypothalamic regulation of reproduction.[J]. Brain Research, 2010, 1364: 116-128. DOI:10.1016/j.brainres.2010.08.059.
[3] MARIA ASMAT F. R M Ramzan. Exogenous Neurokinin B Administration May Have a Strong Effect on Negative Feedback Loop of Hypothalamic Pituitary Thyroid Axis[J]. International Journal of Peptide Research and Therapeutics, 2019, 26 1: 1259-1267. DOI:10.1007/s10989-019-09925-0.

Neurokinin B Preparation Products And Raw materials

Raw materials

Preparation Products

Neurokinin B Suppliers

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NKB NEUROMEDIN K NEUROMEDIN K (HUMAN, PORCINE, BOVINE, RAT, MOUSE) NEUROKININ K NEUROKININ BETA NEUROKININ B (HUMAN, PORCINE) NEUROKININ B (HUMAN, PORCINE, BOVINE, RAT, MOUSE) NEUROKININ B DMHDFFVGLM-NH2 H-ASP-MET-HIS-ASP-PHE-PHE-VAL-GLY-LEU-MET-NH2 ASP-MET-HIS-ASP-PHE-PHE-VAL-GLY-LEU-MET-NH2 BETA-NEUROKININ β-Neurokinin, NeuromedinK L-Asp-L-Met-L-His-L-Asp-L-Phe-L-Phe-L-Val-Gly-L-Leu-L-Met-NH2 Neurokinin B, Neuromedin K, NKB Neurokinin B (pig spinal cord) Neurokinin B (porcine) Neurokinin beta (pig spinal cord) Neuromedin K (pig spinal cord) Porcine neurokinin B Neurokinin B NKB Neurokinin B, ≥95% (HPLC) L-Methioninamide, L-α-aspartyl-L-methionyl-L-histidyl-L-α-aspartyl-L-phenylalanyl-L-phenylalanyl-L-valylglycyl-L-leucyl- NEUROKININ B USP/EP/BP Neurokinin B (swine spinal cord) Neurokinin B (swinespinal cord) (9CI) NKB (DMHDFFVGLM-NH2) 86933-75-7 C55H79N13O14S2 Biochemicals and Reagents Amino Acids and Peptides Agonist BioChemical Tachykinins Peptides Peptide Tachykinin receptor