NALBUPHINE HYDROCHLORIDE
- CAS No.
- 23277-43-2
- Chemical Name:
- NALBUPHINE HYDROCHLORIDE
- Synonyms
- nubain;en2234a;6-alpha)-lph;NalbuphineHCl;nalbufinaclorhidrato;Nabrone hydrochloride;Emorfazone Impurity 4;NALBUPHINE HYDROCHLORIDE;YZLZPSJXMWGIFH-BCXQGASESA-N;NALBUPHINE HYDROCHLORIDE HYDRATE
- CBNumber:
- CB8750372
- Molecular Formula:
- C21H28ClNO4
- Molecular Weight:
- 393.91
- MOL File:
- 23277-43-2.mol
- Modify Date:
- 2023/4/23 13:52:06
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300+H310+H330 |
| Precautionary statements | P260-P262-P264-P280-P302+P352+P310-P304+P340+P310 |
| Hazard Codes | T+,T,F |
| Risk Statements | 26/27/28-39/23/24/25-23/24/25-11 |
| Safety Statements | 22-36/37/39-45-36/37-16 |
| RIDADR | 1544 |
| WGK Germany | 3 |
| RTECS | QD3181000 |
| HazardClass | 6.1(a) |
| PackingGroup | II |
NALBUPHINE HYDROCHLORIDE price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | N4396 | Nalbuphine hydrochloride hydrate ≥98% (HPLC) | 23277-43-2 | 25MG | ₹17222.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | N4396 | Nalbuphine hydrochloride hydrate ≥98% (HPLC) | 23277-43-2 | 100MG | ₹47402.68 | 2022-06-14 | Buy |
NALBUPHINE HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
Nalbuphine is the free base form of Nalbuphine Hydrochloride. Nalbuphine is a mixed opioid agonist-antagonist. Nalbuphine is an analgesic (narcotic).
Acquired resistance
Nalbuphine is an antagonist at μ receptors and an agonist at κ receptors. As an antagonist, it has approximately one-fourth the potency of naloxone, and it produces withdrawal when given to addicts. On a weight basis, the analgesic potency of nalbuphine approaches that of morphine. An intramuscular injection of 10 mg will give about the same degree and duration of analgesia as an equivalent dose of morphine.
Clinical Use
Nalbuphine is only available for parenteral dosage. Its elimination half-life is 2 to 3 hours. Metabolism of nalbuphine is by conjugation of the 3-OH group, and greater than 90% of the drug is excreted as conjugates in the feces.
Side effects
Side effects of nalbuphine are like those of other κ. Dysphoria is not as common as with pentazocine. Sedation is the most common side effect. Nalbuphine does not have the adverse cardiovascular properties found with pentazocine and butorphanol. Nalbuphine has low abuse potential and is not listed under the Controlled Substances Act.
NALBUPHINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
1of2
chevron_rightPreparation Products
23277-43-2(NALBUPHINE HYDROCHLORIDE)Related Search:
1of4
chevron_right