ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Standard Substance >7,8-Dihydro-14-hydroxy- normorphinone

7,8-Dihydro-14-hydroxy- normorphinone

7,8-Dihydro-14-hydroxy- normorphinone Structure
CAS No.
33522-95-1
Chemical Name:
7,8-Dihydro-14-hydroxy- normorphinone
Synonyms
(-)-Noroxymorphone;Naloxone EP Impurity A;7,8-Dihydro-14-hydroxynormorphinone;EN 3169;Noroxymorphone-d4;NoroxyMorphone HCl;Naloxone HCl Impurity;Naltrexone EP Impurity B;Naltrexone EP Impuirty B;4-Hydroxydihydronormorphinone
CBNumber:
CB5927506
Molecular Formula:
C16H17NO4
Molecular Weight:
287.32
MOL File:
33522-95-1.mol
MSDS File:
SDS
Modify Date:
2024/8/14 18:30:21

7,8-Dihydro-14-hydroxy- normorphinone Properties

Melting point >265°C (dec.)
Boiling point 552.1±50.0 °C(Predicted)
Density 1.54±0.1 g/cm3(Predicted)
Flash point 22℃
storage temp. Controlled Substance, -20°C Freezer
solubility DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 10 mg/ml
form A crystalline solid
pka 9.20±0.40(Predicted)
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H301+H311+H331-H370
Precautionary statements  P210-P260-P280-P301+P310-P311
Hazard Codes  T,F
Risk Statements  10-23/24/25-39/23/24/25-11
Safety Statements  36/37-45-16-7
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  1
DEA Controlled Substances CSCN: 9668
CSA SCH: Schedule II
NARC: Yes
NFPA 704
0
3 0

7,8-Dihydro-14-hydroxy- normorphinone Chemical Properties,Uses,Production

Description

Noroxymorphone (Item No. 15903) is an analytical reference standard that is structurally categorized as an opioid. It is an active metabolite of oxycodone , noroxycodone (Item Nos. 15902 | 20407), and oxymorphone that can be detected in plasma and urine. Noroxymorphone is also an immediate precursor in the synthesis of several opioids, including naltrexone (Item Nos. 15520 | ISO60192) and naloxone (Item Nos. 15594 | ISO60191). Noroxymorphone is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.

Chemical Properties

Off-White to Light Brown Solid

Uses

A metabolite of Naloxone and Naltrexone

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4,5α-Epoxy-3,14-dihydroxymorphinan-6-one (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one NoroxyMorphone HCl Morphinan-6-one,4,5-epoxy-3,14-dihydroxy-, (5a)- Noroxymorphone hydrochloride solution Methanol(test NoroxymorphoneHCl,100μg/mLasfreebase) Naloxone HCl Impurity (5alpha)-4,5-epoxy-3,14-dihydroxymorphinan-6-one (5a)-4,5-Epoxy-3,14-dihydroxy-morphinan-6-one 4-Hydroxydihydronormorphinone 7,8-Dihydro-14-hydroxy- normorphinone EN 3169 Naltrexone hydrochloride iMpurity B Naltrexone EP Impurity B (4R,4aS,7aR,12bS)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one Naltrexone EP Impuirty B LTREXONE HYDROCHLORIDE - IMPURITY B Naltrexone Impurity 6 Monomer Naloxone Impurity 7(Naloxone EP Impurity A) Naloxone Hydrochloride Impurit Ⅰ:(5alpha)-4,5-epoxy-3,14-dihydroxymorphinan-6-one Naloxone?Hydrochloride EP Impurity A Nor Oxymorphone (1.0mg/ml in DMSO) Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-, (5α)- (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one Noroxymorphone-d4 Naloxone Hydrochloride Impurit Ⅰ:(5alpha)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 7,8-Dihydro-14-hydroxynormorphinone Naloxone EP Impurity A (-)-Noroxymorphone 4,5α-epoxy-3,14-dihydroxymorphinan-6-one (noroxymorphone) Naltrexone EP Impurity B(Naloxone EP Impurity A) 33522-95-1 Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals