Naltrexone hydrochloride
- CAS No.
- 16676-29-2
- Chemical Name:
- Naltrexone hydrochloride
- Synonyms
- ReVia;Depade;nih8503;en1639a;Nalorex;Antaxone;4-D-butyl;Ccris 1168;NSC 409767;Nalmefene-3
- CBNumber:
- CB7121465
- Molecular Formula:
- C20H24ClNO4
- Molecular Weight:
- 377.87
- MOL File:
- 16676-29-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/9/21 14:52:42
Melting point | 274-2760C |
---|---|
storage temp. | 2-8°C |
solubility | H2O: 50 mg/mL, clear, colorless |
color | White to Off-White |
Water Solubility | Soluble in water at 50mg/ml. |
Sensitive | Light Sensitive |
Merck | 13,6389 |
BRN | 3580333 |
CAS DataBase Reference | 16676-29-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P301+P312+P330 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 22 | |||||||||
Safety Statements | 22-36 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | QD2160000 | |||||||||
F | 8-10 | |||||||||
HS Code | 2932.99.7000 | |||||||||
Toxicity | guinea pig,LD50,oral,1490mg/kg (1490mg/kg),Medicamentos de Actualidad. Vol. 21, Pg. 264, 1985. | |||||||||
NFPA 704 |
|
Naltrexone hydrochloride price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | N3136 | Naltrexone hydrochloride | 16676-29-2 | 100MG | ₹10684.28 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | N3136 | Naltrexone hydrochloride | 16676-29-2 | 250MG | ₹21119.58 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | N3136 | Naltrexone hydrochloride | 16676-29-2 | 1G | ₹58011.18 | 2022-06-14 | Buy |
TCI Chemicals (India) | N1176 | Naltrexone Hydrochloride | 16676-29-2 | 250MG | ₹6300 | 2022-05-26 | Buy |
TCI Chemicals (India) | N1176 | Naltrexone Hydrochloride | 16676-29-2 | 1G | ₹20700 | 2022-05-26 | Buy |
Naltrexone hydrochloride Chemical Properties,Uses,Production
Description
Naltrexone hydrochloride is a potent, long-acting, orally-effective narcotic antagonist useful in the management of narcotic addiction.
Chemical Properties
White Crystalline Powder
Uses
Naltrexone hydrochloride has been used:
as an opioid antagonist, to analyse its effect on ethanol preference using Caenorhabditis elegans as a model.
to determine its effectiveness in reducing the preference for substance of abuse (SOA) like nicotine and cocaine using Caenorhabditis elegans as a model.
in the preparation of combinatorial drug, PXT3003 for treating Charcot-Marie-Tooth disease 1A (CMT1A) transgenic rat model Pmp22.
Biological Activity
Opioid antagonist.
Purification Methods
This narcotic antagonist has been purified by recrystallisation from MeOH and dried in air. The free base has m 168-170o after recrystallisation from Me2CO. [Cone et al. J Pharm Sci 64 618 1975, Gold et al. Med Res Rev 2 211 1982.]
Naltrexone hydrochloride Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Jigs Chemical ltd | +919099003427 | Gujarat, India | 239 | 58 | Inquiry |
Micro Orgo Chem | +91-91-022-24969510 +91-9082984052 | Mumbai, India | 66 | 58 | Inquiry |
Sun Pharmaceutical Industries Ltd | +91-2242244224 +91-2243244324 | Maharashtra, India | 108 | 58 | Inquiry |
Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
Rusan Pharma Ltd | +91-2228687035 +91-9690022465 | Maharashtra, India | 14 | 58 | Inquiry |
Micron Pharmaceuticals | 91-22-24969511 | Maharashtra, India | 43 | 58 | Inquiry |
Deccan Nutraceuticals Pvt. Ltd | +91-9822641298 +91-9822641298 | Mumbai, India | 18 | 58 | Inquiry |
Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
AKASH PHARMA EXPORTS | +91-9388123451 +91-9846039283 | Kerela, India | 470 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Jigs Chemical ltd | 58 |
Micro Orgo Chem | 58 |
Sun Pharmaceutical Industries Ltd | 58 |
Ralington Pharma | 58 |
Rusan Pharma Ltd | 58 |
Micron Pharmaceuticals | 58 |
Deccan Nutraceuticals Pvt. Ltd | 58 |
Rivashaa Agrotech Biopharma Pvt. Ltd. | 58 |
AKASH PHARMA EXPORTS | 58 |
A.J Chemicals | 58 |
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