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O-689

O-689 Structure
CAS No.
166100-39-6
Chemical Name:
O-689
Synonyms
O-689;F-2-ME-AN;Met-F-AEA;FLUOROMETHANANDAMIDE;2-METHYL-2'-FLUORO AEA;(±)-2-Methyl Arachidonoyl-2’(+/-)-2-METHYLARACHIDONYL-2'-FLUOROETHYLAMIDE;(±)-2-Methyl Arachidonoyl-2'-Fluoroethylamide;(+/-)-2-METHYLARACHIDONOYL-2'-FLUOROETHYLAMIDE;(+/-)-2-METHYLARACHIDONOLY-2'*-FLUOROETHYLAMIDE
CBNumber:
CB8757735
Molecular Formula:
C23H38FNO
Molecular Weight:
363.55
MOL File:
166100-39-6.mol
Modify Date:
2023/6/8 9:03:07
Request For Quotation

O-689 Properties

Boiling point 503.6±50.0 °C(Predicted)
Density 0.921±0.06 g/cm3(Predicted)
Flash point 14 °C
storage temp. −20°C
solubility DMF: >10 mg/ml; DMSO: >30 mg/ml; Ethanol: >100 mg/ml; Ethanol:PBS (1:2): 8.5 mg/ml; PBS (pH 7.2): <100 μg/ml
pka 14.98±0.46(Predicted)
form ethanol solution

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P305+P351+P338
Hazard Codes  F,Xi
Risk Statements  11-36/37/38
Safety Statements  7-16-26-36
RIDADR  UN 1170 3/PG 2
WGK Germany  1
NFPA 704
3
0 0

O-689 price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) M1438 (±)-2-Methylarachidonoyl-2′-fluoroethylamide ≥95%, ethanol solution 166100-39-6 5MG ₹19723.15 2022-06-14 Buy
Product number Packaging Price Buy
M1438 5MG ₹19723.15 Buy

O-689 Chemical Properties,Uses,Production

Description

(±)-2-Methyl arachidonoyl-2''-fluoroethylamide (2-Methyl-2''-fluoro AEA) is an analog of anandamide (AEA) in which the alcohol of the ethanolamide group has been removed and replaced with a fluorine atom. This substitution confers considerably increased binding affinity for the CB1 receptor (Ki = 5.7 nM in rat brain). It also confers additional selectivity, in that binding to CB2 is decreased relative to AEA. However, the in vivo activity of 2-fluoro AEA is enhanced much less than the binding affinity, because the analog remains a good substrate for FAAH and is rapidly hydrolyzed by this enzyme. 2-Methyl-2''-fluoro AEA is further modified by the addition of an α-methyl group at the C-2 position of arachidonic acid. This substitution confers enhanced metabolic stability. 2-Methyl-2''-fluoro AEA can fully substitute for Δ9-THC in animal self-administration tests, whereas AEA and 2-fluoro AEA cannot.

O-689 Preparation Products And Raw materials

Raw materials

Preparation Products

O-689 Suppliers

Global( 14)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
EMD Biosciences, Inc. 858 450 5500 United States 6529 66 Inquiry
Spectrum Info. Ltd. 380 44 573 23 97 Ukraine 2742 53 Inquiry
www.vwrsp.com 1-800-932-5000 United States 622 86 Inquiry
SIGMA-RBI 800 736 3690 (Orders) Switzerland 6913 91 Inquiry
Riedel-de Haen AG 800 558-9160 United States 6825 87 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
Energy Chemical 021-58432009 400-005-6266 China 44843 58 Inquiry
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 China 11289 58 Inquiry
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 China 8141 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Supplier Advantage
EMD Biosciences, Inc. 66
Spectrum Info. Ltd. 53
www.vwrsp.com 86
SIGMA-RBI 91
Riedel-de Haen AG 87
Shanghai Hao Zhun Biological Technology Co., Ltd. 58
Energy Chemical 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
Cayman Chemical Company 81

166100-39-6(O-689)Related Search:

AURORA KA-689 ent14,68 DYE ME 689T NB-106-689 ef-689
L-689,560 O-689 2'-FLUORO AEA INSULIN RECEPTOR (689-702) ANTI-PROTEIN KINASE C GAMMA, RAT (681-689)
L-689,560, [4'-3H],L-689,560 [3H] (3H)-L-689,560 Anti-Nicastrin, C-Terminal (689-709), Human (Rabbit) AURORA 689 [TYR680]PROTEIN KINASE C(GAMMA) [681-689] HUMAN, RAT, BOVINE
B-689 ANTI-NICASTRIN, C-TERMINAL (689-709) RABBIT PAB YM-689
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(+/-)-N-(2-FLUOROETHYL)-2-METHYL-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE O-689 (+/-)-2-METHYLARACHIDONOYL-2'-FLUOROETHYLAMIDE (+/-)-2-METHYLARACHIDONYL-2'-FLUOROETHYLAMIDE 2-METHYL-2'-FLUORO AEA F-2-ME-AN FLUOROMETHANANDAMIDE (+/-)-2-METHYLARACHIDONOLY-2'*-FLUOROETHYLAMIDE 2-Methyl-2μ-fluoro AEA, Fluoromethanandamide, O-689 (5Z,8Z,11Z,14Z)-N-(2-fluoroethyl)-2-methylicosa-5,8,11,14-tetraenamide (±)-2-Methyl Arachidonoyl-2&rsquo 5,8,11,14-Eicosatetraenamide, N-(2-fluoroethyl)-2-methyl-, (5Z,8Z,11Z,14Z)- (+/-)-2-Methylarachidonoyl-2'-fluoroethylamide >=95%, ethanol solution Met-F-AEA (±)-2-Methyl Arachidonoyl-2'-Fluoroethylamide 166100-39-6 C23H38NOF