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Dolutegravir Impurity 8

CAS No.: 2244161-72-4

Chemical Name:: Dolutegravir Impurity 8

Synonyms: Dolutegravir Impurity 59;2,6-Di fluoro Dolutegravir;Dolutegravir 2,6-difluoro Impurity;2,6 Difluoro dolutegravir sodium salt;1-Piperazinepropanenitrile,4-(2-methoxyphenyl)-;Dolutegravir 2,6-Difluoro Analog (Dolutegravir 4-Desfluoro 6-Fluoro Impurity);4-Desfluoro-6-fluoro DolutegravirQ: What is 4-Desfluoro-6-fluoro Dolutegravir Q: What is the CAS Number of 4-Desfluoro-6-fluoro Dolutegravir;(4R,12aS)-N-(2,6-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,6-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-

CBNumber:: CB88117623

Molecular Formula:: C20H19F2N3O5

Molecular Weight:: 419.38

MOL File:: 2244161-72-4.mol

Modify Date:: 2024/4/25 17:59:01

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Dolutegravir Impurity 8 Properties

Boiling point	664.9±55.0 °C(Predicted)
Density	1.53±0.1 g/cm3(Predicted)
pka	4.50±1.00(Predicted)

Dolutegravir Impurity 8 Chemical Properties,Uses,Production

Uses

4-Desfluoro-6-fluoro Dolutegravir is impurity C of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir Impurity 8 Preparation Products And Raw materials

Raw materials

Preparation Products

Dolutegravir Impurity 8 Suppliers

Global( 26)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Varanous Labs Pvt Ltd	+91-7036248882 +91-7036248882	Hyderabad, India	1537	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6257	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6739	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6754	58	Inquiry
CR Corporation Limited	+8613062833949	China	8647	58	Inquiry
sgtlifesciences pvt ltd	+8617013299288	China	12373	58	Inquiry
China National Standard Pharmaceutical Corporation Limited	+8615391658522	China	11922	58	Inquiry
ShenZhen H&D Pharmaceutical Technology Co., LTD	+8618627948422	China	3389	58	Inquiry
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD	0755-0755-0755-83725350 13380397412	China	10005	58	Inquiry
ShenZhen H&D Pharmaceutical Technology Co., LTD	18126517264	China	6261	58	Inquiry

Supplier	Advantage
Varanous Labs Pvt Ltd	58
CLEARSYNTH LABS LTD.	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Pharma Affiliates	58
CR Corporation Limited	58
sgtlifesciences pvt ltd	58
China National Standard Pharmaceutical Corporation Limited	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	58
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	58

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2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,6-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)- 2,6-Di fluoro Dolutegravir Dolutegravir 2,6-Difluoro Analog (Dolutegravir 4-Desfluoro 6-Fluoro Impurity) 4-Desfluoro-6-fluoro DolutegravirQ: What is 4-Desfluoro-6-fluoro Dolutegravir Q: What is the CAS Number of 4-Desfluoro-6-fluoro Dolutegravir 2,6 Difluoro dolutegravir sodium salt (4R,12aS)-N-(2,6-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide Dolutegravir 2,6-difluoro Impurity Dolutegravir Impurity 59 1-Piperazinepropanenitrile,4-(2-methoxyphenyl)- 2244161-72-4