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Dolutegravir Impurity 8

Dolutegravir Impurity 8 Structure
CAS No.
2244161-72-4
Chemical Name:
Dolutegravir Impurity 8
Synonyms
Dolutegravir Impurity 59;2,6-Di fluoro Dolutegravir;Dolutegravir 2,6-difluoro Impurity;2,6 Difluoro dolutegravir sodium salt;1-Piperazinepropanenitrile,4-(2-methoxyphenyl)-;Dolutegravir 2,6-Difluoro Analog (Dolutegravir 4-Desfluoro 6-Fluoro Impurity);4-Desfluoro-6-fluoro DolutegravirQ: What is 4-Desfluoro-6-fluoro Dolutegravir Q: What is the CAS Number of 4-Desfluoro-6-fluoro Dolutegravir;(4R,12aS)-N-(2,6-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,6-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
CBNumber:
CB88117623
Molecular Formula:
C20H19F2N3O5
Molecular Weight:
419.38
MOL File:
2244161-72-4.mol
Modify Date:
2024/4/25 17:59:01
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Dolutegravir Impurity 8 Properties

Boiling point 664.9±55.0 °C(Predicted)
Density 1.53±0.1 g/cm3(Predicted)
pka 4.50±1.00(Predicted)

Dolutegravir Impurity 8 Chemical Properties,Uses,Production

Uses

4-Desfluoro-6-fluoro Dolutegravir is impurity C of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir Impurity 8 Preparation Products And Raw materials

Raw materials

Preparation Products

Dolutegravir Impurity 8 Suppliers

Global( 27)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Varanous Labs Pvt Ltd +91-7036248882 +91-7036248882 Hyderabad, India 1541 58 Inquiry
GLP Pharma Standards +91 9866074638 Hyderabad, India 1644 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
CR Corporation Limited +8613062833949 China 8647 58 Inquiry
sgtlifesciences pvt ltd +8617013299288 China 12382 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11927 58 Inquiry
ShenZhen H&D Pharmaceutical Technology Co., LTD +8618627948422 China 3389 58 Inquiry
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD 0755-0755-0755-83725350 13380397412 China 10044 58 Inquiry
Supplier Advantage
Varanous Labs Pvt Ltd 58
GLP Pharma Standards 58
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Pharma Affiliates 58
CR Corporation Limited 58
sgtlifesciences pvt ltd 58
China National Standard Pharmaceutical Corporation Limited 58
ShenZhen H&D Pharmaceutical Technology Co., LTD 58
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD 58

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2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,6-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)- Dolutegravir 2,6-Difluoro Analog (Dolutegravir 4-Desfluoro 6-Fluoro Impurity) 2,6-Di fluoro Dolutegravir 2,6 Difluoro dolutegravir sodium salt 4-Desfluoro-6-fluoro DolutegravirQ: What is 4-Desfluoro-6-fluoro Dolutegravir Q: What is the CAS Number of 4-Desfluoro-6-fluoro Dolutegravir (4R,12aS)-N-(2,6-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide Dolutegravir 2,6-difluoro Impurity Dolutegravir Impurity 59 1-Piperazinepropanenitrile,4-(2-methoxyphenyl)- 2244161-72-4