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Dolutegravir Impurity C

CAS No.: 1802141-49-6

Chemical Name:: Dolutegravir Impurity C

Synonyms: Dolutegravir Impurity 20;Dolutegravir Impurity 23;Dolutegravir Impurity 32;Syringaresinol Impurity 1(Syringaresinol Diglucoside);(4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2:;(4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1'',2'':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-7-ethoxy-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-, (4R,12aS)-

CBNumber:: CB96222324

Molecular Formula:: C22H23F2N3O5

Molecular Weight:: 447.43

MOL File:: 1802141-49-6.mol

Modify Date:: 2022/12/21 16:56:50

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Dolutegravir Impurity C Properties

Boiling point	688.1±55.0 °C(Predicted)
Density	1.42±0.1 g/cm3(Predicted)
pka	10.71±0.40(Predicted)

Dolutegravir Impurity C Chemical Properties,Uses,Production

Uses

O-Ethyl Dolutegravir is an impurity of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir Impurity C Preparation Products And Raw materials

Raw materials

Preparation Products

Dolutegravir Impurity C Suppliers

Global( 8)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Shenzhen Roark Pharma-Tec Co., Ltd.	13128912434	China	2578	58	Inquiry
Molcoo Chemicals Inc.	18672515910	China	9406	58	Inquiry
guoyungurui	18162595016; 18162595016	China	10336	58	Inquiry
ShenZhen H&D Pharmaceutical Technology Co., LTD	13986652530	China	4219	58	Inquiry
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.	020-89854820	China	1081	58	Inquiry

Supplier	Advantage
SynZeal Research Pvt Ltd	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
CLEARSYNTH LABS LTD.	58
Shenzhen Roark Pharma-Tec Co., Ltd.	58
Molcoo Chemicals Inc.	58
guoyungurui	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	58
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.	58

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Dolutegravir Impurity 24

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Dolutegravir Impurity 20 (4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2: Dolutegravir Impurity 23 (4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1'',2'':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-7-ethoxy-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-, (4R,12aS)- Dolutegravir Impurity 32 Syringaresinol Impurity 1(Syringaresinol Diglucoside) 1802141-49-6