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Bucumolol

Bucumolol Structure
CAS No.
58409-59-9
Chemical Name:
Bucumolol
Synonyms
Bucumolol;dl-Bucumolol;8-[3-(tert-Butylamino)-2-hydroxypropoxy]-5-methylcoumarin;8-[2-Hydroxy-3-(tert-butylamino)propoxy]-5-methylcoumarin;8-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-5-methyl-2H-1-benzopyran-2-one
CBNumber:
CB8875453
Molecular Formula:
C17H23NO4
Molecular Weight:
305.37
MOL File:
58409-59-9.mol
Modify Date:
2023/5/4 17:34:40
Request For Quotation

Bucumolol Properties

Melting point >163° (dec.)
Boiling point 490.7±45.0 °C(Predicted)
Density 1.160±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 13.81±0.20(Predicted)
color White to Off-White

Bucumolol Chemical Properties,Uses,Production

Originator

Bucumarol,Sankyo,Japan,1982

Manufacturing Process

A mixture of 3 g of 8-(2-hydroxy-3-chloropropoxy)-5-methyl coumarin, 4.3 g of t-butylamine and 60 ml of ethanol is heated at 100°C in a sealed tube for 15 hours. The reaction mixture is concentrated under reduced pressure to dryness. The residue is recrystallized from a mixture of ethanol and ether to give 2.1 g of the desired product melting at 226° to 228°C (with decomposition).
In practice it is usually used as hydrochloride.

Therapeutic Function

Beta-adrenergic blocker

Bucumolol Preparation Products And Raw materials

Raw materials

tert-Butylamine

Preparation Products

Bucumolol Suppliers

Global( 8)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
3B Scientific Corporation 847.281.9822 United States 6744 47 Inquiry
2A PharmaChem USA (630) 737-0988 United States 6148 39 Inquiry
Waterstone Technology, LLC 317 644 0862 United States 6801 30 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Leancare Ltd. +33 962096793 United Kingdom 6460 42 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
United States Biological 800.520.3011 or 781.639.5092 United States 6256 80 Inquiry
Supplier Advantage
3B Scientific Corporation 47
2A PharmaChem USA 39
Waterstone Technology, LLC 30
Lanospharma Laboratories Co.,Ltd 56
Leancare Ltd. 42
Shanghai Hao Zhun Biological Technology Co., Ltd. 58
United States Biological 80

58409-59-9(Bucumolol)Related Search:

toliprolol moprolol Bucumolol 1-AMINO-3-(2-METHOXY-PHENOXY)-PROPAN-2-OL oxprenolol
3-(2-ethoxyphenoxy)propan-1-amine AKOS BC-1945 bucumolol hydrochloride,dl-Bucumolol hydrochloride
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Bucumolol dl-Bucumolol 8-[2-Hydroxy-3-(tert-butylamino)propoxy]-5-methylcoumarin 8-[3-(tert-Butylamino)-2-hydroxypropoxy]-5-methylcoumarin 8-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-5-methyl-2H-1-benzopyran-2-one 58409-59-9