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bucumolol hydrochloride

bucumolol hydrochloride Structure
CAS No.
36556-75-9
Chemical Name:
bucumolol hydrochloride
Synonyms
CS 359;Bucumarol;Bucumalol;Bucumarol (HCl);bucumolol hydrochloride;dl-Bucumolol hydrochloride;8-(2-Hydroxy-3-tert-butylaminopropoxy)-5-methylcoumarin hydrochloride;DL-5-Methyl-8-(2-hydroxy-3-tert-butylaminopropoxy)coumarin hydrochloride;(+-)-5-Methyl-8-(2-hydroxy-3-tert-butylaminopropoxy)coumarin hydrochloride
CBNumber:
CB5875270
Molecular Formula:
C17H23NO4.ClH
Molecular Weight:
341.833
MOL File:
36556-75-9.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:38
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bucumolol hydrochloride Properties

Melting point 226-228° (dec)

SAFETY

Risk and Safety Statements

Toxicity LD50 in male, female mice (mg/kg): 676, 692 orally; 33.1, 31.6 i.v. (Oshima)

bucumolol hydrochloride Chemical Properties,Uses,Production

Originator

Bucumarol,Sankyo,Japan,1982

Manufacturing Process

A mixture of 3 g of 8-(2-hydroxy-3-chloropropoxy)-5-methyl coumarin, 4.3 g of t-butylamine and 60 ml of ethanol is heated at 100°C in a sealed tube for 15 hours. The reaction mixture is concentrated under reduced pressure to dryness. The residue is recrystallized from a mixture of ethanol and ether to give 2.1 g of the desired product melting at 226° to 228°C (with decomposition).
In practice it is usually used as hydrochloride.

Therapeutic Function

Beta-adrenergic blocker

bucumolol hydrochloride Preparation Products And Raw materials

Raw materials

tert-Butylamine

Preparation Products

bucumolol hydrochloride Suppliers

Global( 6)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24017 58 Inquiry
Shanghai New Union Textra Import & Export Co., Ltd +861-348-227-9455 China 2752 60 Inquiry
Waterstone Technology, LLC 317 644 0862 United States 6801 30 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Supplier Advantage
Career Henan Chemica Co 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58
Shanghai New Union Textra Import & Export Co., Ltd 60
Waterstone Technology, LLC 30
Lanospharma Laboratories Co.,Ltd 56

36556-75-9(bucumolol hydrochloride)Related Search:

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bucumolol hydrochloride Bucumalol (+-)-5-Methyl-8-(2-hydroxy-3-tert-butylaminopropoxy)coumarin hydrochloride 8-(2-Hydroxy-3-tert-butylaminopropoxy)-5-methylcoumarin hydrochloride Bucumarol CS 359 DL-5-Methyl-8-(2-hydroxy-3-tert-butylaminopropoxy)coumarin hydrochloride dl-Bucumolol hydrochloride Bucumarol (HCl) 36556-75-9 C17H23ClNO4