OXPRENOLOL HYDROCHLORIDE
![OXPRENOLOL HYDROCHLORIDE Structure](CAS/GIF/6452-73-9.gif)
- CAS No.
- 6452-73-9
- Chemical Name:
- OXPRENOLOL HYDROCHLORIDE
- Synonyms
- Laracor;Astawal;Katehat;Snering;Paritane;Trasacor;Trasicor;ba-39089;Rixiprol;Ranidrox
- CBNumber:
- CB3332849
- Molecular Formula:
- C15H24ClNO3
- Molecular Weight:
- 301.81
- MOL File:
- 6452-73-9.mol
- Modify Date:
- 2024/7/2 8:55:06
Melting point | 91-93°C |
---|---|
storage temp. | Store at +4°C |
solubility | Very soluble in water, freely soluble in alcohol. |
form | Solid |
color | White to off-white |
CAS DataBase Reference | 6452-73-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS06 |
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Signal word | Danger | |||||||||
Hazard statements | H301 | |||||||||
Precautionary statements | P264-P270-P301+P310+P330-P405-P501 | |||||||||
Hazard Codes | Xi | |||||||||
RIDADR | UN 2811 6.1 / PGIII | |||||||||
RTECS | UA5277000 | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 2922190900 | |||||||||
Toxicity | LD50 oral in rat: 214mg/kg | |||||||||
NFPA 704 |
|
OXPRENOLOL HYDROCHLORIDE Chemical Properties,Uses,Production
Description
Oxprenolol is an orally bioavailable β-adrenergic receptor (β-AR) antagonist (Ki = 7.10 nM in a radioligand binding assay using rat heart tissue). It is non-selective and binds to both β1- and β2-ARs (Kds = 2.09 and 1.35 nM in isolated rat heart and uterus, respectively). Oxprenolol is selective for β-ARs over serotonin (5-HT) receptors in rat sarcolemmal membrane preparations (IC50s = 4.13 and 23,300 nM, respectively), but it binds to 5-HT1A receptors in rat hippocampus and 5-HT1B in rat striatum (Kis = 94.2 and 642 nM, respectively). Formulations containing oxprenolol have been used to treat hypertension and angina pectoris.
Chemical Properties
White Solid
Uses
β-Adrenergic blocker. Antihypertensive, antianginal, antiarrhythmic.
Biological Activity
Non-selective β -adrenergic antagonist.
OXPRENOLOL HYDROCHLORIDE Preparation Products And Raw materials
OXPRENOLOL HYDROCHLORIDE Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | China | 9030 | 58 | Inquiry |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |
Finetech Industry Limited | +86-27-87465837 +8618971612321 | China | 9626 | 58 | Inquiry |
LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | China | 33350 | 58 | Inquiry |
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