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Alprenolol

Alprenolol Structure
CAS No.
13655-52-2
Chemical Name:
Alprenolol
Synonyms
Alpheprol;Alprenolol;ALLPRENOLOL;dl-Alprenolol;(RS)-Alprenolol;Alprenolol USP/EP/BP;(-)-Alprenolol hydrate D-tartrate;3-(o-Allylphenoxy)-1-isopropylamino-2-propanol;1-Isopropylamino-3-(2-allyl)phenoxypropan-2-ol;1-(2-Allylphenoxy)-3-(isopropylamino)-2-propanol
CBNumber:
CB7874989
Molecular Formula:
C15H23NO2
Molecular Weight:
249.35
MOL File:
13655-52-2.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:17

Alprenolol Properties

Melting point 57.5°C
Boiling point 392.45°C (rough estimate)
Density 1.0065 (rough estimate)
refractive index 1.5250 (estimate)
storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMSO: 15 mg/ml; Ethanol: 5 mg/ml; PBS (pH 7.2): 1 mg/ml
form A crystalline solid
pka pKa 9.63 (Uncertain)
color White to off-white
Water Solubility 366.9mg/L(22.5 ºC)
NIST Chemistry Reference 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propenyl)phenoxy]-(13655-52-2)

SAFETY

Risk and Safety Statements

Hazard Codes  T
Risk Statements  23/24/25-43
Safety Statements  36/37/39-45
RIDADR  3249
HazardClass  6.1(b)
PackingGroup  III
Toxicity mammal (species unspecified),LD50,intraperitoneal,102mg/kg (102mg/kg),Pharmaceutical Chemistry Journal Vol. 8, Pg. 137, 1974.

Alprenolol Chemical Properties,Uses,Production

Description

Occupational cases of contact dermatitis caused by exposure to alprenolol have been reported within the pharmaceutical industry.

Uses

Antiadrenergic (β-receptor).

Definition

ChEBI: A secondary alcohol that is propan-2-ol substituted by a 2-allylphenoxy group at position 1 and an isopropylamino group at position 3. It is a beta-adrenergic antagonist used as a antihypertensive, anti-arrhythmia and a sympatholytic agent.

Contact allergens

Occupational cases of contact dermatitis due to this betablocker were reported in the pharmaceutical industry

Alprenolol Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 51)Suppliers
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Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
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InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
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SHANGHAI KEAN TECHNOLOGY CO., LTD. +8613817748580 China 40067 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
MedChemExpress 021-58955995 United States 6398 58 Inquiry
Alprenolol 1-Isopropylamino-3-(2-allyl)phenoxypropan-2-ol 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propenyl)phenoxy]- Alpheprol dl-Alprenolol ALLPRENOLOL (-)-Alprenolol hydrate D-tartrate 1-(2-Allylphenoxy)-3-(isopropylamino)-2-propanol 1-(Isopropylamino)-3-[2-(2-propenyl)phenoxy]-2-propanol 3-(o-Allylphenoxy)-1-isopropylamino-2-propanol [S,(-)]-3-[2-(2-Propenyl)phenoxy]-1-isopropylamino-2-propanol (R)-3-[2-(2-Propenyl)phenoxy]-1-isopropylamino-2-propanol [R,(+)]-3-[2-(2-Propenyl)phenoxy]-1-isopropylamino-2-propanol 1-(Isopropylamino)-3-(2-allylphenoxy)-2-propanol {2-hydroxy-3-[2-(prop-2-en-1-yl)phenoxy]propyl}(propan-2-yl)amine (RS)-Alprenolol 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propen-1-yl)phenoxy]- Alprenolol USP/EP/BP anti-arrhythmic,5-hydroxytryptamine Receptor,anti-hypertensive,Inhibitor,Alprenolol,inhibit,Serotonin Receptor,anti-anginal,5-HT Receptor,β-adrenoceptor,5-HT1B,5-HT1A 13655-52-2 C15H23NO2C4H6O6