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nifurfoline

nifurfoline Structure
CAS No.
3363-58-4
Chemical Name:
nifurfoline
Synonyms
nifurfoline;3-[(Morpholino)methyl]-1-[(5-nitrofurfurylidene)amino]hydantoin;2,4-Imidazolidinedione, 3-(4-morpholinylmethyl)-1-[[(5-nitro-2-furanyl)methylene]amino]-;3-(morpholin-4-ylmethyl)-1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione
CBNumber:
CB8911340
Molecular Formula:
C13H15N5O6
Molecular Weight:
337.29
MOL File:
3363-58-4.mol
Modify Date:
2023/5/4 17:34:37
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nifurfoline Properties

Melting point 206°; also reported as mp 194-196°
Boiling point 486.5±55.0 °C(Predicted)
Density 1.63±0.1 g/cm3(Predicted)
pka 5.39±0.10(Predicted)

nifurfoline Chemical Properties,Uses,Production

Originator

Furobactil,Carrion,France,1974

Manufacturing Process

20 g of nitrofurantoin are placed in 100 cc of dimethylformamide and the solution is heated to 75°C to 80°C. This temperature is maintained and 100 cc of 40% formaldehyde are added, followed by 10 g of freshly distilled morpholine. The heating is continued for one hour, the mixture cooled and filtered and the precipitate obtained is washed with 95% alcohol. 20 g of the desired product are obtained as yellow crystals which melt at 206°C.

Therapeutic Function

Antibacterial

nifurfoline Preparation Products And Raw materials

Raw materials

Morpholine Nitrofurantoin Formaldehyde

Preparation Products

nifurfoline Suppliers

Global( 4)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Service Chemical Inc. 888-895-6920 Germany 6373 71 Inquiry
Shanghai New Union Textra Import & Export Co., Ltd +861-348-227-9455 China 2752 60 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 17691182729 18161915376 China 10010 58 Inquiry
Supplier Advantage
Service Chemical Inc. 71
Shanghai New Union Textra Import & Export Co., Ltd 60
Lanospharma Laboratories Co.,Ltd 56
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 58

3363-58-4(nifurfoline)Related Search:

Nifuratel Nitrofurantoin 1-Aminohydantoin hydrochloride Nitrofurazone Nifursemizone
2-Furaldehyde, semicarbazone 2-FURALDEHYDE DIMETHYLHYDRAZONE nifurfoline Nifuradene
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3-[(Morpholino)methyl]-1-[(5-nitrofurfurylidene)amino]hydantoin nifurfoline 3-(morpholin-4-ylmethyl)-1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione 2,4-Imidazolidinedione, 3-(4-morpholinylmethyl)-1-[[(5-nitro-2-furanyl)methylene]amino]- 3363-58-4