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thenalidine

CAS No.: 86-12-4

Chemical Name:: thenalidine

Synonyms: Thenalidin;Sandostene;Thenaldine;thenalidine;Thenophenopiperidine;thenalidine USP/EP/BP;1-Methyl-4-[phenyl(2-thienylmethyl)amino]piperidine;4-Piperidinamine, 1-methyl-N-phenyl-N-(2-thienylmethyl)-

CBNumber:: CB8914477

Molecular Formula:: C17H22N2S

Molecular Weight:: 286.43

MOL File:: 86-12-4.mol

Modify Date:: 2024/3/19 15:37:51

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thenalidine Properties

Melting point	95-97°
Boiling point	bp0.02 158-160°
Density	1.140±0.06 g/cm3(Predicted)
pka	pKa 3.36±0.06(H2O t undefined I = 0.30 (NaCl)) (Uncertain);8.39±0.07(H2O t undefined I = 0.30 (NaCl)) (Uncertain)

thenalidine Chemical Properties,Uses,Production

Uses

Thenalidine is an antihistamine that has anticholinergic properties which is used as an antipruritic drugs.

brand name

Sanbosten.

World Health Organization (WHO)

Thenalidine, a piperidine antihistamine, was introduced in 1953 for the management of dermatologic and allergic conditions. By 1958 its use had been associated with cases of severe neutropenia, two of them fatal, which led to its withdrawal in the United States of America and subsequently in the United Kingdom. Over the next fifteen years, continued reports of its association with cases of neutropenia resulted in further withdrawals in many countries. It is apparently still available, however, in some combination products.

thenalidine Preparation Products And Raw materials

Raw materials

4-Piperidinamine, 1-methyl-N-(2-thienylmethyl)- N-(1-METHYLPIPERIDIN-4-YL)ANILINE Bromobenzene 2-(Chloromethyl)thiophene

Preparation Products

thenalidine Suppliers

Global( 7)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Shaanxi Didu New Materials Co. Ltd	+86-89586680 +86-13289823923	China	9003	58	Inquiry
kemikalieimport	+ 45 - 2034 3359	Europe	6699	47	Inquiry
ecochem international chemical broker	+45 45 42 34 36	Europe	6385	66	Inquiry
Lanospharma Laboratories Co.,Ltd	13440048448	China	6343	56	Inquiry
United States Biological	800.520.3011 or 781.639.5092	United States	6256	80	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
Shaanxi Didu New Materials Co. Ltd	58
kemikalieimport	47
ecochem international chemical broker	66
Lanospharma Laboratories Co.,Ltd	56
United States Biological	80

86-12-4(thenalidine)Related Search:

N-(1-ACETYLPIPERIDIN-4-YL)-N-(2,3-DIHYDRO-1-(METHYLSULPHONYL)-(1H)-INDOL-5-YL)THIOPHENE-2-CARBOXAMIDE thenalidine tartrate N-(1-ACETYL-2,3-DIHYDRO-(1H)-INDOL-5-YL)-N-(1-BENZYLPIPERIDIN-4-YL)THIOPHENE-2-CARBOXAMIDE N-(1-BENZYLPIPERIDIN-4-YL)-N-(2,3-DIHYDRO-1-(METHYLSULPHONYL)-(1H)-INDOL-5-YL)THIOPHENE-2-CARBOXAMIDE N-(1-ACETYL-2,3-DIHYDRO-(1H)-INDOL-6-YL)-N-(1-BENZYLPIPERIDIN-4-YL)THIOPHENE-2-CARBOXAMIDE

N-(1-ACETYL-2,3-DIHYDRO-(1H)-INDOL-5-YL)-N-(1-ACETYLPIPERIDIN-4-YL)THIOPHENE-2-CARBOXAMIDE N-(1-ACETYL-2,3-DIHYDRO-(1H)-INDOL-5-YL)-N-(1-PROPYLPIPERIDIN-4-YL)-THIOPHENE-2-CARBOXAMIDE N-[2-METHYL-1H-INDOL-5-YL]-N-[1-(2-PHENYLETHYL)PIPERIDIN-4-YL]THIOPHENE-2-CARBOXAMIDE N-(1-ACETYL-2,3-DIHYDRO-(1H)-INDOL-6-YL)-N-(1-METHYLPIPERIDIN-4-YL)THIOPHENE-2-CARBOXAMIDE N-(1-ACETYLPIPERIDIN-4-YL)-N-(2-TERT-BUTYL-(1H)-INDOL-5-YL)THIOPHENE-2-CARBOXAMIDE

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thenalidine 1-Methyl-4-[phenyl(2-thienylmethyl)amino]piperidine Sandostene Thenalidin Thenophenopiperidine Thenaldine 4-Piperidinamine, 1-methyl-N-phenyl-N-(2-thienylmethyl)- thenalidine USP/EP/BP 86-12-4