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2-hydroxypropyl-α-cyclodextrin

2-hydroxypropyl-α-cyclodextrin Structure
CAS No.
128446-33-3
Chemical Name:
2-hydroxypropyl-α-cyclodextrin
Synonyms
HPACD;Cavasol? W6 HP;2-hydroxypropyl-α-cyclodextrin;(2-Hydroxyethyl)-a-cyclodextrin;Hydroxpropyl Alpha Cyclodextrim;(2-Hydroxypropyl)-a-cyclodextrin;α-Cyclodextrin, 2-hydroxypropyl ethers;HYDROXYPROPYL-ALPHA-CYCLODEXTRIN, MS=0.6;.alpha.-Cyclodextrin, 2-hydroxypropyl ethers;(2-Hydroxypropyl)-alpha-cyclodextrin average Mw ~1,180
CBNumber:
CB8971454
Molecular Formula:
Molecular Weight:
0
MOL File:
Mol file
Modify Date:
2024/6/6 17:55:34

2-hydroxypropyl-α-cyclodextrin Properties

Melting point 245 °C (dec.)(lit.)
Density 1.39 at 24.6℃
solubility Soluble in water, methanol, DMF. Insoluble in acetone, chloroform.
form Solid powder
color White to off white
optical activity [α]20/D +125°, c = 1 in H2O
LogP -10.6--9.89
Surface tension 66.1mN/m at 1g/L and 20℃
EPA Substance Registry System .alpha.-Cyclodextrin, 2-hydroxypropyl ethers (128446-33-3)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P
WGK Germany  3

2-hydroxypropyl-α-cyclodextrin price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 390690 (2-Hydroxypropyl)-α-cyclodextrin average Mw ~1,180 128446-33-3 5G ₹4741.35 2022-06-14 Buy
Sigma-Aldrich(India) 390690 (2-Hydroxypropyl)-α-cyclodextrin average Mw ~1,180 128446-33-3 25G ₹10879.13 2022-06-14 Buy
Product number Packaging Price Buy
390690 5G ₹4741.35 Buy
390690 25G ₹10879.13 Buy

2-hydroxypropyl-α-cyclodextrin Chemical Properties,Uses,Production

Uses

  • (2-Hydroxypropyl)-α-cyclodextrin can be used as a chiral selector to resolve tryptophan racemate by capillary electrophoresis.
  • It can be used to synthesize biodegradable polyrotaxanes for fabricating blood-contacting devices.
  • Co-polymer based on (2-hydroxypropyl)-α-cyclodextrin cross-linked with polyethylenimine can be used as a gene delivery vector.
  • It can also be used as stabilizer for antibacterial iodine formulations, as it forms a stable inclusion complex with iodine and improves aqueous solubility.

General Description

(2-Hydroxypropyl)-α-cyclodextrin is a hydroxyalkyl derivative of cyclodextrin, which is generally used as a substitute of α-cyclodextrin for potential application in food, cosmetics and pharmaceutical industries. It may be used as a parenteral drug carrier on account of its attractive characteristics such as: a greater extent of solubility in water, high dissolution capacity for weakly soluble analytes, and low toxicity.

2-hydroxypropyl-α-cyclodextrin Preparation Products And Raw materials

Raw materials

Preparation Products

2-hydroxypropyl-α-cyclodextrin Suppliers

Global( 57)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Wuhan Fortuna Chemical Co., Ltd +86-027-59207850 China 5989 58 Inquiry
Shandong Deshang Chemical Co., Ltd. +86-0531-8875-2665 +8613153039501 China 646 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Zhengzhou Alfa Chemical Co.,Ltd +8618530059196 China 13256 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30250 58 Inquiry
CD Chemical Group Limited +8615986615575 China 20356 58 Inquiry
Alfa Chemistry United States 24072 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
Hebei Kingfiner Technology Development Co.Ltd +86-15532196582 +86-15373005021 China 2989 58 Inquiry
Wuhan Mayue Longteng Technology Development Co., Ltd. +undefined15171477138 China 293 58 Inquiry
Cavasol? W6 HP HYDROXYPROPYL-ALPHA-CYCLODEXTRIN, MS=0.6 .alpha.-Cyclodextrin, 2-hydroxypropyl ethers (2-Hydroxypropyl)-alpha-cyclodextrin average Mw ~1,180 (2-Hydroxypropyl)-a-cyclodextrin HPACD (2-Hydroxyethyl)-a-cyclodextrin 2-hydroxypropyl-α-cyclodextrin Hydroxpropyl Alpha Cyclodextrim α-Cyclodextrin, 2-hydroxypropyl ethers 128446-33-3 Chelation/Complexation Compounds Cyclodextrins Synthetic Reagents