SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE

CAS No.: 165377-44-6

Chemical Name:: SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE

Synonyms: SA-4503;CS-2246;SA-4503(2HCl);Cutamesine HCl;SA 4503;SA-4503;SA4503 >=98% (HPLC);Cutamesine hydrochloride;AGY94806 dihydrochloride;SA 4503 (dihydrochloride);Cutamesine dihydrochloride

CBNumber:: CB91011619

Molecular Formula:: C23H32N2O2.2ClH

Molecular Weight:: 441.44

MOL File:: 165377-44-6.mol

MSDS File:: SDS

Modify Date:: 2025/4/17 18:22:24

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SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE Properties

Melting point	250-252°C
storage temp.	2-8°C
solubility	Soluble in DMSO (up to 5 mg/ml) or in Water (up to at least 25 mg/ml)..
form	powder
color	white to beige
Water Solubility	H2O: 2mg/mL, clear
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.

SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	SML2181	SA4503 ≥98% (HPLC)	165377-44-6	5MG	₹10955.7	2022-06-14	Buy
Sigma-Aldrich(India)	SML2181	SA4503 ≥98% (HPLC)	165377-44-6	25MG	₹44155.8	2022-06-14	Buy

Product number	Packaging	Price	Buy
SML2181	5MG	₹10955.7	Buy
SML2181	25MG	₹44155.8	Buy

SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE Chemical Properties,Uses,Production

Uses

SA 4503 Dihydrochloride is a novel and selective σ1 receptor agonist.

Biochem/physiol Actions

SA4503 is a high affinity, orally active non-opioid intracellular receptor sigma-1 (σ1R) selective agonist (IC50 = 17.4 nM against 200 nM (+)-pentazocine for binding σ1R), exhibiting ~100-fold less affinity for the sigma 2 receptor subtype (σ2R) and little or no affinity toward 36 other receptors, ion channels and second messenger systems. Oral administration is reported to elicit cerebral acetylcholine (ACh) release in rat frontal cortex and hippocampus (5-20 mg/kg p.o.) and reduce immobility time in a mouse forced swimming test (Immobility time = 214.8 s without vs. 111.6 s with 1.0 mg/kg oral dosage).

SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE Suppliers

Global( 110)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6100	58	Inquiry
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	China	29730	60	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	33024	60	Inquiry
BOC Sciences	+1-631-485-4226	United States	19552	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49732	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29808	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	32159	58	Inquiry
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	China	52849	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10473	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6391	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
BOC Sciences	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
TargetMol Chemicals Inc.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58

SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE Spectrum

SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE(165377-44-6)¹HNMR

165377-44-6(SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE)Related Search:

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1-(2-PHENYLETHYL)PIPERAZINE 1-(3-PHENYLPROPYL)PIPERAZINE

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SA 4503 (dihydrochloride) Cutamesine dihydrochloride 1-[2-(3,4-DiMethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride SA-4503 SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE 1-(3,4-Dimethoxyphenethyl)-4-(3-phenylpropyl)piperazinedihydrochloride 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine hydrochloride SA-4503(2HCl) Cutamesine HCl (SA-4503 HCl) Cutamesine HCl Cutamesine hydrochloride SA4503; SA 4503; SA-4503; AGY94806; AGY-94806; AGY 94806; CUTAMESINE HCL; CUTAMESINE HYDROCHLORIDE AGY94806 dihydrochloride SA4503 DIHYDROCHLORIDE;AGY94806 DIHYDROCHLORIDE CS-2246 SA 4503;SA-4503 SA4503 >=98% (HPLC) 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazin... Cutamesine dihydrochloride, 10 mM in DMSO Cutamesine (SA4503 ) dihydrochloride 165377-44-6 C23H32N2O22HCl C23H34Cl2N2O2 C23H32N2O22ClH