ANP 1-28, HUMAN

- CAS No.
- 89213-87-6
- Chemical Name:
- ANP 1-28, HUMAN
- Synonyms
- Carperitide;ATRIAL NATRIURETIC PEPTIDE HUMAN;SLRRSSCFGGRMDRIGAQSGLGCNSFRY;ATRIAL NATRIURETIC FACTOR (1-28) (HUMAN, PORCINE);HANF;α-hANP;carperitida;ANP HUMAN, 1-28;ANP 1-28, HUMAN;ANF 1-28, HUMAN
- CBNumber:
- CB9116087
- Molecular Formula:
- C127H203N45O39S3
- Molecular Weight:
- 3080.44
- MOL File:
- 89213-87-6.mol
- Modify Date:
- 2024/11/26 10:35:11
Density | 1.55±0.1 g/cm3(Predicted) |
---|---|
storage temp. | Store at -20°C |
solubility | Water: 1 mg/ml |
form | A lyophilized powder |
Sequence | H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH,(Disulfide bridge: Cys-Cys) |
InChIKey | NSQLIUXCMFBZME-VUEHYBQXNA-N |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
---|---|
Signal word | Warning |
Hazard statements | H361 |
Precautionary statements | P201-P202-P281-P308+P313-P405-P501 |
ANP 1-28, HUMAN Chemical Properties,Uses,Production
Description
Carperitide is the α-human atrial natriuretic peptide (α-hANP) produced by recombinant technology. It was introduced in Japan as a treatment for acute congestive heart failure (CHF). In dogs with CHF, carperitide significantly reduced the elevated left ventricular end-diastolic pressure and the index of myocardial oxygen consumption (systolic blood pressure x heart rate). In a clinical trial, carperitide was effective in improving hemodynamics and symptoms in 60% of patients with acute CHF. Carperitide was reported to be well tolerated with no significant adverse effects clinically. A beneficial effect on hemodynamics has been reported in chronic heart failure patients. Carperitide is also in clinical trials for maintenance of blood pressure during surgical operations.
Uses
Treatment of decompensated congestive heart failure.
ANP 1-28, HUMAN Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Shandong Huizhihan Supply Chain Co., Ltd | +86-13363081709 +86-13363000288 | China | 300 | 58 | Inquiry |
Hebei Yanxi Chemical Co., Ltd. | +8617531153977 | China | 5854 | 58 | Inquiry |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | China | 10983 | 58 | Inquiry |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | China | 615 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29858 | 58 | Inquiry |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10406 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19552 | 58 | Inquiry |
Cellmano Biotech Limited | 0551-65326643 18156095617 | China | 995 | 58 | Inquiry |
Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | China | 12806 | 58 | Inquiry |
Hebei Bonster Technology Co.,Limited | +8613315996897 | China | 792 | 58 | Inquiry |