MONACOLIN J
- CAS No.
- 79952-42-4
- Chemical Name:
- MONACOLIN J
- Synonyms
- (4R,6R)-;monacolin J;Simvastatin?imp?H;Lovastatin Impurity 8;Lovastatin Diol Lactone;Lovastatin Lactone Diol;SiMvastatin Lactone Diol;Simvastatin EP Impurity H;Simvastatin EP Impurity 8;Simvastatin EP Impurity H (4R-Isomer)
- CBNumber:
- CB91175997
- Molecular Formula:
- C19H28O4
- Molecular Weight:
- 320.42322
- MOL File:
- 79952-42-4.mol
- Modify Date:
- 2023/5/18 11:31:15
| Melting point | 50-53°C |
|---|---|
| Boiling point | 535.7±50.0 °C(Predicted) |
| Density | 1.17±0.1 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| solubility | Chloroform (Slightly), DMF, DMSO, Methanol (Slightly) |
| form | Solid |
| pka | 13.49±0.40(Predicted) |
| color | White to Pale Yellow |
| Stability | Hygroscopic |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
MONACOLIN J Chemical Properties,Uses,Production
Chemical Properties
Tan Solid
Uses
Monacolin J is a Simvastatin intermediate; Lovastatin analog has the activities of decreasing blood cholesterol and low-d. lipoprotein, can be used to preparation hypolipidemic medicine.
Definition
ChEBI: A polyketide that is monacolin L bearing an additional hydroxy substituent at position 8.
MONACOLIN J Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 67)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Scinva Chemicals and Pharmaceuticals Pvt Ltd | +91-7406196725 +91-7406196725 | Karnataka, India | 71 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| sgtlifesciences pvt ltd | +8617013299288 | China | 12382 | 58 | Inquiry |
| Alfa Chemistry | +1-5166625404 | United States | 21317 | 58 | Inquiry |
| LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
79952-42-4(MONACOLIN J)Related Search:
chevron_left
1of3
chevron_right
6(R)-[2-(8(S)-Hydroxy]-2(S),6(R)-dimethyl-1,2,6,7,8,8a(R)-hexahydro-1(S)-naphthyl]ethyl-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one
(4R,6R)-
SiMvastatin Lactone Diol
Lovastatin Lactone Diol
Lovastatin Diol Lactone
monacolin J
(4R,6R)-4-Hydroxy-6-(2-((1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl)tetrahydro-2H-pyran-2-one
Simvastatin EP Impurity H
Lovastatin Impurity 8
2H-Pyran-2-one, 6-[2-[(1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthalenyl]ethyl]tetrahydro-4-hydroxy-, (4R,6R)-
Simvastatin?imp?H
Lovastatin Lactone Diol (Simvastatin EP Impurity H/ Simvastatin Lactone Diol)
Simvastatin EP Impurity H (Simvastatin Lactone Diol/ Lovastatin Lactone Diol)
(4RS,6R)-4-Hydroxy-6-[2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8ahexahydronaphthalen-1-yl]ethyl]tetrahydro-2H-pyran-2-one
Autophagy,inhibit,Inhibitor,Monacolin J,HMG-CoA Reductase (HMGCR)
Simvastatin EP Impurity H (4R)-Diastereomer
Simvastatin EP Impurity H (4R-Isomer)
Simvastatin EP Impurity 8
Lovastatin Diol Lactone ((4R,6R)-6-[2-[(1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-Hexahydro-8-hydroxy-2,6-dimethyl-1-naphthalenyl]ethyl]tetrahydro-4-hydroxy-2H-pyran-2-one)
79952-42-4
Chiral Reagents
Drug Analogues
Inhibitors
Intermediates & Fine Chemicals
Pharmaceuticals