Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >API >Antipyretic analgesics >Nonsteroidal Anti-Inflammatory Drugs (NSAIDS) >Cefovecin sodium

Cefovecin sodium

Cefovecin sodium Structure
CAS No.
141195-77-9
Chemical Name:
Cefovecin sodium
Synonyms
UK287;UK 287;D01681;C13142;074-02;UK-287;UK287,074-02;UK 287,074-02;UK-287,074-02;Cefovecin SodiuM
CBNumber:
CB91260675
Molecular Formula:
C17H18N5NaO6S2
Molecular Weight:
0
MOL File:
141195-77-9.mol
MSDS File:
SDS
Modify Date:
2024/3/8 9:17:02
Request For Quotation

Cefovecin sodium Properties

storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
InChIKey QRIBXVGHDLFNNE-RUPIGQPYNA-M
SMILES [Na+].N12[C@@]([H])([C@H](NC(/C(/C3=CSC(N)=N3)=N/OC)=O)C1=O)SCC([C@@H]1CCCO1)=C2C([O-])=O |&1:2,4,23,r|

Cefovecin sodium Chemical Properties,Uses,Production

Description

Cefovecin sodium is a semi-synthetic broad-spectrum antibacterial agent from the cephalosporin class of chemotherapeutic agents. Cefovecin is the non-proprietary designation for (6R,7R)-7- [[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[(2S)-tetrahydro-2-furanyl]-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monosodium salt.
Cefovecin Sodium is an antibiotic of the cephalosporin class. It is used for the treatment of skin infections caused by Pasturella multocida in cats, and Staphylococcus intermedius/S. canis in dogs. Cefovecin Sodium is the first single-dose injectable antibiotic for dogs and cats.

Uses

Sodium salt of Cefovecin, a cephalosporin antibiotic used in the treatment of skin conditions in dogs and cats.

Indications

Dogs
Cefovecin sodium is indicated for the treatment of skin infections (secondary superficial pyoderma, abscesses, and wounds) in dogs caused by susceptible strains of Staphylococcus intermedius and Streptococcus canis (Group G).
Cats
Cefovecin sodium is indicated for the treatment of skin infections (wounds and abscesses) in cats caused by susceptible strains of Pasteurella multocida.

Side effects

In cats, the most common effects are vomiting, diarrhea, decreased appetite, lethargy, hyperactivity or “acting strange” and inappropriate urination.
In dogs, the most common adverse effects were lethargy, decreased appetite, vomiting, diarrhea, blood in feces, dehydration, and flatulence.

Safety

Dogs
CONVENIA administered to healthy four month old dogs at doses of 12 mg/kg (1.5 X), 36 mg/kg (4.5 X), and 60 mg/kg (7.5 X) every seven days by dorsoscapular subcutaneous injections was well-tolerated for a total of 5 doses. Vomiting and diarrhea were seen in all treatment groups, with the incidence of vomiting and the incidence and duration of diarrhea increasing in a dose-related manner. Injection site irritation and transient edema occurred with increasing frequency in a dose-related manner and with repeat injections. Two injection site reactions included a seroma over the shoulder and swelling lasting > 30 days. Dogs dosed at 36 mg/kg had a significant (p = 0.0088) increase in BUN (all means remained within the normal range) compared to the controls. One dog dosed at 60 mg/kg exhibited a glomerulopathy on histopathology, and one dog in this same group had minimal peliosis hepatis. At an exaggerated dose of 180 mg/kg (22.5X) in dogs, CONVENIA caused some injection site irritation, vocalization and edema. Edema resolved within 8-24 hours.
www.zoetisus.com

Cefovecin sodium Preparation Products And Raw materials

Raw materials

Preparation Products

Cefovecin sodium Suppliers

Global( 48)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Masteam Bio-tech Co., Ltd. +86-15200345168 +86-15200345168 CHINA 153 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
ENBRIDGE PHARMTECH CO., LTD. +8613812269233 China 303 58 Inquiry
Shanghai UCHEM Inc. +862156762820 +86-13564624040 China 6931 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
Wuhan Fortuna Chemical Co., Ltd +86-027-59207850 China 5964 58 Inquiry
Baoji Guokang Healthchem co.,ltd +8615604608665 15604608665 CHINA 9427 58 Inquiry
Alfa Chemistry +1-5166625404 United States 21317 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Masteam Bio-tech Co., Ltd. 58
BOC Sciences 58
ENBRIDGE PHARMTECH CO., LTD. 58
Shanghai UCHEM Inc. 58
AFINE CHEMICALS LIMITED 58
Wuhan Fortuna Chemical Co., Ltd 58
Baoji Guokang Healthchem co.,ltd 58
Alfa Chemistry 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58

Related articles

  • Effects of Cefovecin Sodium
  • Cefovecin Sodium, also known as Convenia, is an antibiotic of the cephalosporin class, licensed for the treatment of skin infe....
  • Jan 19，2022

141195-77-9(Cefovecin sodium)Related Search:

Cefoxitin Cefditoren pivoxil Cefoxitin sodium Cefditoren (6R,7R)
Ceftezole sodium Cefotetan Toltrazuril 4-(Aminomethyl)benzoic acid Diclazuril
Etimicin Sulphate ULINASTATIN Octreotide PotassiuM sodiuM Dehydroandrographolide Succinate
chevron_left

1of3

chevron_right
sodium (6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl] amino]-8-oxo-3-[(2S)-oxolan-2-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene- 2-carboxylate Cefovecin SodiuM Ceftrexine sodium 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[(2S)-tetrahydro-2-furanyl]-,sodium salt (1:1), (6R,7R)- 074-02 C13142 D01681 UK 287 UK287 UK-287 UK 287,074-02 UK-287,074-02 UK287,074-02 (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-[(2S)-oxolan-2-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Cefovecin Sodium Salt Cofovecin Sodium Sodium (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-Thiazol-4-Yl)-2-Methoxyiminoacetyl]Amino]-8-Oxo-3-[(2S)-Oxolan-2-Yl]-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate 141195-77-9 C17H18N5O6S2Na Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds 1