indicine-N-oxide
- CAS No.
- 41708-76-3
- Chemical Name:
- indicine-N-oxide
- Synonyms
- NSC132319;Indicin-N-oxid;indicine-N-oxide;(+)-Indicine N-oxide;DNAWGBOKUFFVMB-PZIGJSDBSA-N;(7R,8R)-7-hydroxy-4-oxido-5,6,7,8-tetrahydro-3H-pyrrolizin-4-ium-1-yl]methyl (2R)-2-hydroxy-2-[(1S)-1-hydroxyethyl]-3-methylbutanoate;Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, [(1R,7aS)-2,3,5,7a-tetrahydro-1-hydroxy-4-oxido-1H-pyrrolizin-7-yl]methyl ester, (2R,3S)-
- CBNumber:
- CB91364920
- Molecular Formula:
- C15H25NO6
- Molecular Weight:
- 315.36
- MOL File:
- 41708-76-3.mol
- Modify Date:
- 2022/12/21 16:56:50
indicine-N-oxide Chemical Properties,Uses,Production
Description
Heliotropiurn indicurn also contains this base which has the structure given above based upon comparison with the preceding alkaloid. The base has proved to be highly active against transplanted neoplasts, Walker-256 carcinosarcoma, melanoma B-16, leukaemia L-12l 0, leukaemia P-388 and leukaemia P-1534 in mice and rats, giving up to 91 per cent inhibition of transplanted growth at a daily dosage of 200 mgm. per kilo.
Uses
Indicine N-oxide is a pyrrolizidine alkaloid that is isolated from Heliotropium indicum, one of the most widely used herbs in India. Indicine N-oxide exhibits antitumour and antimitotic activity in humans, and has subsequently undergone Phase I & II trials in adults and children with leukemia and solid tumours.
References
Rao, McBride., U.S. Patent, 3,717,710 February 20,1973
indicine-N-oxide Preparation Products And Raw materials
Raw materials
Preparation Products
indicine-N-oxide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Changzhou Xianglong Pharmaceutical Technology Co., LTD | 18661161657 | China | 9998 | 58 | Inquiry |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-021-61109150 | China | 31163 | 58 | Inquiry |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 18108052721 | China | 5182 | 58 | Inquiry |
| Shanghai Beiwanta Biotechnology Co., Ltd. | 021-67187366 19901745723 | China | 9254 | 58 | Inquiry |
| Chengdu Push Bio-Technology Co., Ltd. | 18080489829 | China | 9209 | 58 | Inquiry |
| Shanghai Moqi Biological Technology Co., LTD | 021-38218169 13341702378 | China | 9118 | 58 | Inquiry |
| Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | China | 9371 | 60 | Inquiry |
| Naturewill Biotechnology Co., Ltd. | 18113192475 18113192475 | China | 5001 | 58 | Inquiry |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | China | 4552 | 58 | Inquiry |