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5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid Structure
CAS No.
356068-93-4
Chemical Name:
5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
Synonyms
Des-N-(2-Diethylaminoethyl)amide Sunitinib Acid;5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl...;Cefatrizine Propylene Glycol Impurity 1(Cefatrizine Propylene Glycol EP Impurity A);(Z)-5-[(5-Fluoro-2-oxoindolin-3-ylidene)methyl]-2,4-dimethylpyrrole-3-carboxylic Acid;(Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)Methyl)-2,4-diMethyl-1H-pyrrole-3-carboxylic acid;5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid;(3Z)-3-[(3,5-Dimethyl-4-carboxy-1H-pyrrol-2-yl)methylidene]-5-fluoro-1,3-dihydro-2H-indol-2-on;(3Z)-3-[(3,5-DiMethyl-4-carboxy-1H-pyrrol-2-yl)Methylidene]-5-fluoro-1,3-dihydro-2H-indol-2-one;5-(5-Fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl)-2,4-dimethyl-1H-pyrrol-3-carboxylic acid;5-(5-Fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
CBNumber:
CB91503983
Molecular Formula:
C16H13FN2O3
Molecular Weight:
300.28
MOL File:
356068-93-4.mol
MSDS File:
SDS
Modify Date:
2023/6/19 22:07:10
Request For Quotation

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid Properties

Melting point 320 °C (decomp)
Boiling point 588.4±50.0 °C(Predicted)
Density 1.454±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Aqueous Base (Slightly, Heated), DMSO (Slightly, Heated)
form Solid
pka 5.79±0.50(Predicted)
color Dark Orange
InChI InChI=1S/C16H13FN2O3/c1-7-13(18-8(2)14(7)16(21)22)6-11-10-5-9(17)3-4-12(10)19-15(11)20/h3-6,18H,1-2H3,(H,19,20)(H,21,22)/b11-6-
InChIKey RBHBOUYXUXWCNJ-WDZFZDKYSA-N
SMILES N1C(/C=C2/C3=C(NC/2=O)C=CC(F)=C3)=C(C)C(C(O)=O)=C1C

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid Chemical Properties,Uses,Production

Chemical Properties

Brown crystals

Uses

Des-N-(2-Diethylaminoethyl)amide Sunitinib Acid is an impurity of Sunitinib (S819995), a multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK). Antineoplastic.

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid Preparation Products And Raw materials

Raw materials

1H-Indole, 5-fluoro-1-(trimethylsilyl)-2-[(trimethylsilyl)oxy]- Ethyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate 5-Formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid 2,4-Dimethylpyrrole-3-carboxylicacid 5-Fluoro-2-oxindole
3,5-Dimethylpyrrole-2,4-dicarboxylic acid 2-t-butyl ester-4-ethyl ester Piperidine 5-Fluoroisatin Pyrrolidine
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Preparation Products

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5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid Suppliers

Global( 129)Suppliers
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Raising Sun Pharma +91-9399941155 +91-9399941155 Telangana, India 127 58 Inquiry
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Supplier Advantage
Raising Sun Pharma 58
KKyemistry (India) Pvt. Ltd. 50
Manus Aktteva 34
Trignokem International 50
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
Huanfu Industrial Co.，（Shanghai）Ltd. 58
Capot Chemical Co.,Ltd. 60
Shanghai Daken Advanced Materials Co.,Ltd 58
ATK CHEMICAL COMPANY LIMITED 60
5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)Methyl)-2,4-diMethyl-1H-pyrrole-3-carboxylic acid (3Z)-3-[(3,5-DiMethyl-4-carboxy-1H-pyrrol-2-yl)Methylidene]-5-fluoro-1,3-dihydro-2H-indol-2-one (3Z)-3-[(3,5-Dimethyl-4-carboxy-1H-pyrrol-2-yl)methylidene]-5-fluoro-1,3-dihydro-2H-indol-2-on Des-N-(2-Diethylaminoethyl)amide Sunitinib Acid 1H-Pyrrole-3-carboxylic acid, 5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl- 5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl... (Z)-5-[(5-Fluoro-2-oxoindolin-3-ylidene)methyl]-2,4-dimethylpyrrole-3-carboxylic Acid 5-(5-Fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid 5-(5-Fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl)-2,4-dimethyl-1H-pyrrol-3-carboxylic acid Cefatrizine Propylene Glycol Impurity 1(Cefatrizine Propylene Glycol EP Impurity A) 5-[(Z)(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid 356068-93-4