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(R)-(+)-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE

(R)-(+)-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE Structure
CAS No.
119838-44-7
Chemical Name:
(R)-(+)-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE
Synonyms
R-BOC-BMI;(R)-(+)-1-(TERT-BUTOXYCARBONYL)-2-T-BUT&;(R)-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE;(R)-1-Boc-2-tert-butyl-3-methylimidazolidin-4-one;(R)-(+)-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE;(R)-(+)-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE 99%;N-(tert-butoxycarbonyl)-2-butyl-3-methyl-4-imidazolidinone;t-Butyl 2-t-Butyl-3-methyl-4-oxo-1-imidazolidinecarboxylate;(R)-1-Boc-2-tert-butyl-3-methyl-4-imidazolidinone≥ 99% (Titration);(R)-(+)-1-(TERT-BUTOXYCARBONYL)-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINE
CBNumber:
CB9166082
Molecular Formula:
C13H24N2O3
Molecular Weight:
256.34
MOL File:
119838-44-7.mol
MSDS File:
SDS
Modify Date:
2024/12/26 11:48:19
Request For Quotation

(R)-(+)-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE Properties

Melting point 68-70 °C(lit.)
Boiling point 399.58°C (rough estimate)
Density 1.0600 (rough estimate)
refractive index 1.4365
storage temp. Sealed in dry,2-8°C
pka -0.60±0.40(Predicted)
form crystalline solid
color colorless

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3
F  8-10
HS Code  29332100

(R)-(+)-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

(R)-(+)-1-Boc-2-tert-butyl-3-methyl-4-imidazolidinone is a chiral glycine derivative used for the synthesis of amino acids.

Synthesis

The commercial glycine N-methylamide hydrochloride is converted to the racemic imidazolidinone (2) by imine formation with Pivalaldehyde and cyclization under acidic conditions (eq 1). The mandelate salt of like configuration is less soluble and is used for highly efficient resolution; subsequent treatment with Boc anhydride (Di-t-butyl Dicarbonate) gives the enantiomeric Boc-BMI (1) (eq 2).
(R)-( )-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE

References

1. Fitzi, R.; Seebach, D. T 1988, 5277.
2. Seebach, D.; Fitzi, R. Ger. Patent 3 604 591, 1986 (CA 1988, 108, 94 944j).
3. Seebach, D.; Dziadulewicz, E.; Behrendt, L.; Cantoreggi, S.; Fitzi, R. LA 1989, 1215.

(R)-(+)-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE Preparation Products And Raw materials

Raw materials

4-IMidazolidinone, 2-(1,1-diMethylethyl)-3-Methyl- (S)-(-)-1-(TERT-BUTOXYCARBONYL)-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE Di-tert-butyl dicarbonate

Preparation Products

(R)-(+)-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE Suppliers

Global( 33)Suppliers
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GRG LIFE SCIENCES +918074868135 Hyderabad, India 47 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43340 58 Inquiry
Suzhou ARTK Medchem Co., Ltd. +86-512-68323658 +86-18168183658 China 39003 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131957 58 Inquiry
Combi-Blocks Inc. 858 635 8950 United States 6618 69 Inquiry
Aikon International Limited 025-58859352 18068836627 China 15494 58 Inquiry
Nanjing Becas pharmatech Ltd. 13912903754 China 2664 58 Inquiry
Tianjin Derchemist Science & Technology Co., Ltd. 22-58627059 13920586291 China 3594 50 Inquiry
Taizhou Nanfeng Pharmaceutical Research Institute 18616377689 China 20010 58 Inquiry
Supplier Advantage
GRG LIFE SCIENCES 58
A.J Chemicals 58
LEAPCHEM CO., LTD. 58
Suzhou ARTK Medchem Co., Ltd. 58
Amadis Chemical Company Limited 58
Combi-Blocks Inc. 69
Aikon International Limited 58
Nanjing Becas pharmatech Ltd. 58
Tianjin Derchemist Science & Technology Co., Ltd. 50
Taizhou Nanfeng Pharmaceutical Research Institute 58

119838-44-7((R)-(+)-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE)Related Search:

(S)-(-)-1-(TERT-BUTOXYCARBONYL)-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE Carbamic acid, [2-(propylamino)ethyl]-, 1,1-dimethylethyl ester (9CI) (2-AMINO-ETHYL)-PROPYL-CARBAMIC ACID TERT-BUTYL ESTER (R)-(+)-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE CARBAMIC ACID, [2-(DIMETHYLAMINO)ETHYL]-, 1,1-DIMETHYLETHYL ESTER
tert-Butyl (2-aminoethyl)(ethyl)carbamate tert-butyl N-[2-(dimethylamino)-2-oxoethyl]carbamate N-Boc-N-methylethylenediamine
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(R)-(+)-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE (R)-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE (R)-(+)-1-(TERT-BUTOXYCARBONYL)-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINE (R)-(+)-1-(TERT-BUTOXYCARBONYL)-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE R-BOC-BMI (R)-(+)-1-(TERT-BUTOXYCARBONYL)-2-T-BUT& (R)-(+)-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE 99% (R)-(+)-1-(TERT-BUTOXYCARBONYL)-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE 99% N-(tert-butoxycarbonyl)-2-butyl-3-methyl-4-imidazolidinone (R)-(+)-1-(tert-Butoxycarbonyl)-2-tert-butyl-3-methyl-4-imidazolidinone,99% (R)-1-BOC-2-(TERT-BUTYL)-3-METHYL-4-IMIDAZOLIDINONE;(R)-(+)-1-BOC-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE (R)-tert-Butyl 2-(tert-butyl)-3-Methyl-4-oxoiMidazolidine-1-carboxylate t-Butyl 2-t-Butyl-3-methyl-4-oxo-1-imidazolidinecarboxylate (R)-1-Boc-2-tert-butyl-3-methylimidazolidin-4-one (R)-1-Boc-2-tert-butyl-3-methyl-4-imidazolidinone≥ 99% (Titration) (2R)-2-tert-butyl-3-methyl-4-oxo-1-imidazolidinecarboxylic acid tert-butyl ester 1-Imidazolidinecarboxylic acid, 2-(1,1-dimethylethyl)-3-methyl-4-oxo-, 1,1-dimethylethyl ester, (2R)- Tert-butyl (R)-2-(tert-butyl)-3-methyl-4-oxoimidazolidine-1-carboxylate 119838-44-7 Precursors for Amino Acid Synthesis Peptide Synthesis Specialty Synthesis