TEMAZEPAM
- CAS No.
- 846-50-4
- Chemical Name:
- TEMAZEPAM
- Synonyms
- er115;k3917;wy3917;wy2917;Planum;ER 115;K-3917;Wy-3917;WY 2917;Cerepax
- CBNumber:
- CB9185627
- Molecular Formula:
- C16H13ClN2O2
- Molecular Weight:
- 300.74
- MOL File:
- 846-50-4.mol
- Modify Date:
- 2023/6/8 9:03:07
| Melting point | 119-121°C |
|---|---|
| Boiling point | 211°C (rough estimate) |
| Density | 1.2682 (rough estimate) |
| refractive index | 1.5200 (estimate) |
| Flash point | 11 °C |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, freely soluble in methylene chloride, sparingly soluble in ethanol (96 per cent). |
| pka | pKa 1.6 (Uncertain) |
| BCS Class | 2 |
| CAS DataBase Reference | 846-50-4(CAS DataBase Reference) |
| IARC | 3 (Vol. 66) 1996 |
| EPA Substance Registry System | Temazepam (846-50-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| Hazard Codes | Xn,T,F | |||||||||
| Risk Statements | 22-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 16-36/37-45-7 | |||||||||
| RIDADR | UN 1230 3/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DF1225000 | |||||||||
| HS Code | 2933910000 | |||||||||
| Toxicity | LD50 oral in rat: 2gm/kg | |||||||||
| NFPA 704 |
|
TEMAZEPAM Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Uses
Temazepam, is pharmacologically active metabolite of Diazepam (D416855). It is Sedative, and hypnotic. Controlled substance (depressant).
World Health Organization (WHO)
Temazepam is a widely used benzodiazepine derivative. As with other drugs in this class, cases of misuse and drug dependence are known.
General Description
Temazepam, 7-chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl -2H-1,4-benzodiazepine-2-one(Restoril), also occurs as a minor metabolite of diazepam.It can be visualized as N-methyl oxazepam, and indeed, asmall amount of N-demethylation occurs slowly. However,metabolism proceeds mainly through glucuronidationof the 3-hydroxyl group, thus, it is intermediate acting andmarketed as a hypnotic said to have little or no residualeffect.
TEMAZEPAM Preparation Products And Raw materials
846-50-4(TEMAZEPAM)Related Search:
Temazepam-metabolite
Temazepam acetate
TEMAZEPAM IMPURITY F
7-chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one
TEMAZEPAM-D5,100/MLINMETHANOL,TEMAZEPAM-D5
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1of4
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Planum
Remestan
Restoril
Ro 5-5345
ro5-5345
Ro-5-5354
Signopam
WY 2917
wy2917
wy3917
Wy-3917
7-Chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
7-chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-2h-4-benzodiazepin-2-one
7-Chloro-3-hydroxy-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
Cerepax
Crisonar
Diazepam, 3-hydroxy
ER 115
er115
Euhypnos
Euipnos
Gelthix
Hydroxydiazepam
k3917
K-3917
Levanxene
Levanxol
Levanzene
Mabertin
Methyloxazepam
N-Methyloxazepam
Normison
Oxydiazepam
Perdorm
AURORA KA-7273
TEMAZEPAM,1.0MG/MLINMETHANOL
NSC 246303
3-Hydroxydiazepam-13C,d3
7-Chloro-1,3-dihydro-3-hydroxy-1-(methyl-13C,d3)-5-phenyl-2H-1,4-benzodiazepin-2-one
ER 115-13C,d3
N-Methyloxazepam-13C,d3
Normison-13C,d3
Oxydiazepam-13C,d3
Perdorm-13C,d3
Remestan-13C,d3
Restoril-13C,d3
Temazepam-13C,d3
Temazepam solution
Hydroxydrazepam
7-chloro-3-hydroxy-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2-one
Temazepam CIV (200 mg)
Temazepam [Controlled Substance]
Methanol(test Temazepam,1.0mg/mL)
temazepam methanol solution
temazepam--dea schedule iv item
TeMazepaM (100 μg/ML in Methanol)
1,3-Dihydro-7-chloro-3-hydroxy-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-3-hydroxy-1-methyl-5-phenyl-