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CLOBAZAM

CLOBAZAM Structure
CAS No.
22316-47-8
Chemical Name:
CLOBAZAM
Synonyms
Mystan;Chlorepin;clobazammethanolsolution;7-Chloro-1,5-dihydro-1-methyl-5-phenyl-1,5-benzodiazepine-2,4(3H)-dione;hr376;HR 376;h-4723;H 4723;RU-4723;lm-2717
CBNumber:
CB9205925
Molecular Formula:
C16H13ClN2O2
Molecular Weight:
300.74
MOL File:
22316-47-8.mol
Modify Date:
2023/5/15 10:44:01
Request For Quotation

CLOBAZAM Properties

Melting point 162-164°C
Boiling point 211°C (rough estimate)
Density 1.2682 (rough estimate)
refractive index 1.5200 (estimate)
Flash point 11 °C
storage temp. 2-8°C
solubility Slightly soluble in water, freely soluble in methylene chloride, sparingly soluble in alcohol.
form Solid
pka 8.59±0.20(Predicted)
color White to Off-White
CAS DataBase Reference 22316-47-8(CAS DataBase Reference)
EPA Substance Registry System 1H-1,5-Benzodiazepine-2,4(3H,5H)-dione, 7-chloro-1-methyl-5-phenyl- (22316-47-8)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H301+H311+H331-H370
Precautionary statements  P210-P260-P280-P301+P310-P311
Hazard Codes  F,T
Risk Statements  11-23/24/25-39/23/24/25
Safety Statements  16-36/37-45-24/25-22-7
RIDADR  3249
WGK Germany  3
RTECS  DE9600000
HazardClass  6.1(b)
PackingGroup  III

CLOBAZAM Chemical Properties,Uses,Production

Chemical Properties

N/AWhite Solid

Uses

Benzodiazepine psychotherapeutic agent. Clobazam (CLB) has proven efficacy against multiple seizure types. Controlled substance (depressant).

Definition

ChEBI: 7-Chloro-1H-1,5-benzodiazepine-2,4(3H,5H)-dione in which the hydrogen attached to the nitrogen at position 1 is substituted by a methyl group, whilst that attached to the other nitrogen is substitute by a phenyl group. It is used for the short-term management of acute anxiety and as an adjunct in the treatment of epilepsy in association with other antiepileptics.

Safety Profile

Poison by ingestion and intraperitoneal routes. Moderately toxic by subcutaneous route. Human systemic effects by ingestion: wakefulness, withdrawal, nausea and vomiting. An experimental teratogen. Other experimental reproductive effects. A tranquhzer. When heated to decomposition it emits very toxic fumes of NOx and Cl-. See also DIAZEPAM.

CLOBAZAM Preparation Products And Raw materials

Raw materials

Iodomethane Sodium Ethanol

Preparation Products

22316-47-8(CLOBAZAM)Related Search:

N,N-DIPHENYLFORMAMIDE CLOBAZAM H-BETA-ALA-NH2 HCL 3-(dimethylamino)-N,N-dimethylpropionamide 3-CHLORODIPHENYLAMINE
N,N-DIPHENYLACETAMIDE lofendazam 5-CHLORO-2-(ETHYLAMINO)ANILINE MALONANILIDE 1,2,3,4-tetrahydrobenzo(e)(1,4)diazepin-5-one
1,5-Dihydro-benzo[b][1,4]diazepine-2,4-dione 8-CHLORO-1,3,4,5-TETRAHYDRO-2H-1,5-BENZODIAZEPIN-2-ONE 2,3,4,5-TETRAHYDRO-1H-BENZO[B][1,4]DIAZEPINE N,N,N',N'-TETRAMETHYL-O-PHENYLENEDIAMINE 1-Methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine
N,N'-dimethylmalonamide N-(2-aminophenyl)propanamide N,N,N',N'-TETRAMETHYLMALONAMIDE
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h-4723 HR 376 hr376 LM 2717 lm-2717 RU-4723 Urbac 3363-58-4 Urbadan Urbanyl CLOBAZAM 7-CHLORO-1-METHYL-5-PHENYL-1H-1,5-BENZODIAZEPINE-2,4-[3H,5H]-DIONE 1,2-Dimethoxyethane (test Clobazam, 1.0 mg/mL ) Clobazam solution ClobazepaM FriziuM NSC 336279 CLOBAZAM--DEA SCHEDULE IV ITEM CLOBAZAM,1.0MG/MLINMETHANOL 1H-1,5-Benzodiazepine-2,4(3H,5H)-dione, 7-chloro-1-methyl-5-phenyl- 1H-1,5-benzodiazepine-2,4(3H,5H)-dione,7-chloro- 1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3h-1,5-benzodiazepin 1-Phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine 4(3h,5h)-dione,7-chloro-1-methyl-5-phenyl-1h-5-benzodiazepine-2 Clorepin Frisium H 4723 CLOBAZAM USP/EP/BP ClobazamQ: What is Clobazam Q: What is the CAS Number of Clobazam Q: What is the storage condition of Clobazam Mystan 7-Chloro-1,5-dihydro-1-methyl-5-phenyl-1,5-benzodiazepine-2,4(3H)-dione Chlorepin clobazammethanolsolution Clobazam CIV (100 mg) 22316-47-8 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Active Pharmaceutical Ingredients