Hygromycin B
- CAS No.
- 31282-04-9
- Chemical Name:
- Hygromycin B
- Synonyms
- HYGROMYCIN B HYDRATE;950U/MG;Hygromix;Hygrovetin;hygromix-8;hygrovetine;hygromix2.4;hydromycinb;antihelmycin;Hyaromycin B
- CBNumber:
- CB9219683
- Molecular Formula:
- C20H37N3O13
- Molecular Weight:
- 527.52
- MOL File:
- 31282-04-9.mol
- Modify Date:
- 2024/5/29 17:48:59
| Melting point | 160-180°C |
|---|---|
| alpha | D20 +20.2° (c = 1 in water) |
| Boiling point | 608.13°C (rough estimate) |
| Density | 1.4252 (rough estimate) |
| refractive index | 1.6300 (estimate) |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 30 days. |
| form | powder |
| pka | 7.1, 8.8(at 25℃) |
| color | faintly brown to brown |
| PH | pH (25g/l, 25℃ ) : 9.5～12.5 |
| Water Solubility | Miscible with water, methanol, buffer solution and ethanol. Immiscible with less polar solvents. |
| Merck | 14,4852 |
| BRN | 6755837 |
| Stability | Hygroscopic |
| EPA Substance Registry System | Hygromycin B (31282-04-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300+H330 | |||||||||
| Precautionary statements | P260-P264-P270-P271-P284-P304+P340+P310 | |||||||||
| Hazard Codes | T+,Xn,T | |||||||||
| Risk Statements | 26/27/28-41-42/43-40-36-23/24/25 | |||||||||
| Safety Statements | 23-26-28-36/37/39-45-22-36-36/37 | |||||||||
| RIDADR | UN 3462 6.1/PG 1 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | WK2130000 | |||||||||
| F | 19 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | I | |||||||||
| HS Code | 29419059 | |||||||||
| Toxicity | mmo-esc 250 mg/L AACHAX 18,798,80 | |||||||||
| NFPA 704 |
|
Hygromycin B price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | H9773 | Hygromycin B from Streptomyces hygroscopicus suitable for plant cell culture, BioReagent, ≥60% (HPLC), lyophilized powder | 31282-04-9 | 50MG | ₹6646.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | H9773 | Hygromycin B from Streptomyces hygroscopicus suitable for plant cell culture, BioReagent, ≥60% (HPLC), lyophilized powder | 31282-04-9 | 100MG | ₹11301.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | H7772 | Hygromycin B from Streptomyces hygroscopicus lyophilized powder | 31282-04-9 | 50MG | ₹4730.53 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | H9773 | Hygromycin B from Streptomyces hygroscopicus suitable for plant cell culture, BioReagent, ≥60% (HPLC), lyophilized powder | 31282-04-9 | 250MG | ₹20968.03 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | H7772 | Hygromycin B from Streptomyces hygroscopicus lyophilized powder | 31282-04-9 | 100MG | ₹7209.45 | 2022-06-14 | Buy |
Hygromycin B Chemical Properties,Uses,Production
Description
Hygromycin B is an aminoglycoside antibiotic that has been found in S. hygroscopicus. It is active against E. coli (MIC = 150 μg/ml) and cytotoxic to both prokaryotic and eukaryotic cells via inhibition of protein synthesis. Hygromycin B has commonly been used in molecular and cell biology applications to select for transformed cells expressing the E. coli hygromycin resistance genes hyg or hph.
Chemical Properties
White to off-white lyophilized powder
Uses
Hygromycin B, a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome
Application
Hygromycin B was found in the culture broth of Streptomyces hygroscopicus by Lilly Research Laboratories in 1953, as a mixture with hygromycin A. It showed activity against a variety of gram-positive and gram-negative bacteria as well as fungi. Hygromycin B has been used for therapy of helminthic infections in swine and poultry.
General Description
Amorphous solid or tan powder.
Air & Water Reactions
Water soluble.
Reactivity Profile
Weakly basic.
Fire Hazard
Flash point data for Hygromycin B are not available; however Hygromycin B is probably combustible.
Safety Profile
Poison by intraperitoneal route. Mutation data reported. When heated to decomposition it emits toxic fumes of Nox
Hygromycin B Preparation Products And Raw materials
Global( 361)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Biopharmacule Speciality Chemicals P Ltd (India) | +91 40 6462 1866 | Hyderabad, India | 526 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Anand Agencies | 91-20-24454597 | Maharashtra, India | 2337 | 58 | Inquiry |
31282-04-9(Hygromycin B)Related Search:
chevron_left
1of4
chevron_right
antihelmycin
hydromycinb
hygromix2.4
hygromix-8
hygrovetine
Hygromycin Solution
Hygromix
5-O-(2,3-O-(6-Amino-6-desoxyheptapyranosyliden)-beta-D-talopyranosyl)-desoxy-N'-methyl-D-streptamin
Hygrovetin
O-6-Amino-6-deoxy-
Hygromycin B, powder
Hygromycin B, PBS solution
HygroMycin B, OMniPur(R)
hygromycin B aqueous solution
hygromycin B from streptomyces*hygroscopicus
hygromycin B plant cell culture tested
hygromycin B solution from streptomyces hygroscopicus
Hygromycin B solution Streptomyces hygroscopicus
HYGROMYCIN B FROM STREPTOMYCES*HYGROSCOP ICUS LYOPHI
HYGROMYCIN B FROM STREPTOMYCES*HYGROSCOP ICUS, CELL
Hygromycin B from Streptomyces hygroscopicus from Streptomyces hygrosco
HYGROMYCIN B 85+%
HYGROMYCIN B 98+%
HygromycinB,Streptomyceshygroscopicus,HighPurity,inDIWater
HygromycinB,HighPurity,Solid,CellCultureTested
HygromycinB,Streptomyceshygroscopicus,ConcentratedSolution
HygromycinB,Streptomyceshygroscopicus,HighPurity,inPBSBuffer
D-Streptamine, O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1?2-3)-O-.beta.-D-talopyranosyl-(1?5)-2-deoxy-N3-methyl-
Hyaromycin B
HYGROMYCIN B, HIGH PURITY, POWDER, CELL CULTURE TESTED
HYGROMYCIN B, HIGH PURITY, IN HEPES BUFFER, CELL CULTURE TESTED
HYGROMYCIN B, HIGH PURITY, IN DI WATER, CELL CULTURE TESTED
HYGROMYCIN B, HIGH PURITY, IN PBS BUFFER, CELL CULTURE TESTED
O-6-Amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1-2-3)-O-β-D-talopyranosyl(1-5)-2-deoxy-N3-methyl-D-streptamine
950U/MG
D-Streptamine, O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1→2-3)-O-β-D-talopyranosyl-(1→5)-2-deoxy-N3-methyl-
Hygromycin B
O-6-Amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1-2-3)-o-beta-D-talopyranosyl-(1-5)-2-deoxy-N3-methyl-D-streptamine
Hygromycin B Solution, 100ppm
Hygromycin B solution,1000ppm
Hygromycin B from Streptomyces hygroscopicus Vetec(TM) reagent grade
UREA 8M SOLUTION PROTEOMICS GRADE
Hygromycin B fromStreptomyces hygroscopicus≥ 90% (HPLC)
Hygromycin B solution from Biological Fermentation
HYGROMYCIN B, STREPTOMYCES HYGROSCOPICUS
HYGROMYCIN B, STREPTOMYCES SPECIES
HYGROGOLD(TM)
O-6-AMINO-6-DEOXY-L-GLYCERO-D-GALACTOHEPTAPYRANOSYLIDENE-(1,2,3)-O-BETA-D-TALOPYRANOSYL-(1,5)-2-DEOXY-N3-METHYL-D-STREPTAMINE
o-6-amino-6-deoxy-l-glycero-d-galacto-heptopyranosylidene-(1-2-3)-o-beta-d-talopyranosyl-(1-5)-2-deoxy-n3-methyl-d-streptamine
O-6-AMINO-6-DEOXY-L-GLYCERO-D-GALACTO-HEPTOPYRANOSYLIDENE-(1-2-3)-O-BETA-D-TALOPYRANOSYL(1-5)-2-DEOXY-N3-METHYL-D-STREPTAMINE
)-o-beta-d-talopyranosyl-(1-5)-2-deoxy-n-(sup3)-methyl-
Hygromycin B
HYGROMYCIN B--100 mg/mL WATER
HYGROMYCIN B--1000 UNIT POWDER
HYGROMYCIN B--50 mg/mL PBS
Hygromycin B, 80%, from Streptomyces hygroscopicus
Hygromycin B, Streptomyces sp. - CAS 31282-04-9 - Calbiochem
Hygromycin B, Streptomyces sp., Cell Culture-Tested - CAS 31282-04-9 - Calbiochem
Hygromycin B, Streptomyces sp., Sterile-Filtered Solution in 25 mM HEPES, Cell Culture-Tested - CAS 31282-04-9 - Calbiochem