MIRA-1

CAS No.: 72835-26-8

Chemical Name:: MIRA-1

Synonyms: MIRA-1;NSC 19630;p53 Activator VIII;WRN Helicase Inhibitor;1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2;(2,5-dioxopyrrol-1-yl)methyl propanoate;5-dihydro-1H-pyrrol-1-yl)methyl propionate;Ethyl 2,5-Dioxo-2,5-dihydropyrrole-1-acetate;1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 1-[(1-oxopropoxy)methyl]-

CBNumber:: CB92514665

Molecular Formula:: C8H9NO4

Molecular Weight:: 183.16

MOL File:: 72835-26-8.mol

Modify Date:: 2024/7/2 8:55:41

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MIRA-1 Properties

Melting point	44 °C
Boiling point	298.2±23.0 °C(Predicted)
Density	1.307±0.06 g/cm3(Predicted)
storage temp.	Store at +4°C
solubility	Soluble to 100 mM in DMSO and to 100 mM in ethanol
form	Powder
pka	-2.79±0.20(Predicted)
color	White to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338

MIRA-1 price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	681647	WRN Helicase Inhibitor, NSC 19630 - CAS 72835-26-8 - Calbiochem The WRN Helicase Inhibitor, NSC 19630, also referenced under CAS 72835-26-8, controls the biological activity of WRN Helicase. This small molecule/inh	72835-26-8	5MG	₹10670	2022-06-14	Buy

Product number	Packaging	Price	Buy
681647	5MG	₹10670	Buy

MIRA-1 Chemical Properties,Uses,Production

Uses

The tumor suppressor gene, p53, is often mutated in most human cancers. MIRA-1 is a maleimide-derived molecule that can reactivate the mutant p53 leading to apoptosis in human tumor cells. In addition, the MIRA scaffold is an attractive lead for developing anticancer drugs that target mutant p53.

MIRA-1 Preparation Products And Raw materials

Raw materials

N-MALEIMIDOMETHANOL Propionic anhydride

Preparation Products

MIRA-1 Suppliers

Global( 49)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry
Suzhou ARTK Medchem Co., Ltd.	+8618168183658	China	39010	58	Inquiry
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	China	4658	58	Inquiry
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd.	025-66061636 18013972705	China	8263	58	Inquiry
Shanghai SuperLan Chemcial Technique Centre	021-2022843681 15618226720	China	9082	58	Inquiry
Suzhou Zhixin Biotechnology Co., Ltd.	0512-65118909 15162312715	China	2997	58	Inquiry
Bide Pharmatech Ltd.	400-164-7117 13681763483	China	41463	60	Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd.	+86-18521732826	China	48465	58	Inquiry
PharmaBlock Sciences (Nanjing), Inc.	025-86918232 4000255188	China	9792	58	Inquiry

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Suzhou ARTK Medchem Co., Ltd.	58
Nantong QuanYi Biotechnology Co., Ltd	58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd.	58
Shanghai SuperLan Chemcial Technique Centre	58
Suzhou Zhixin Biotechnology Co., Ltd.	58
Bide Pharmatech Ltd.	60
Shanghai Aladdin Biochemical Technology Co.,Ltd.	58
PharmaBlock Sciences (Nanjing), Inc.	58

MIRA-1 1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione NSC 19630 1H-Pyrrole-2,5-dione, 1-[(1-oxopropoxy)methyl]- Ethyl 2,5-Dioxo-2,5-dihydropyrrole-1-acetate 1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2 5-dihydro-1H-pyrrol-1-yl)methyl propionate p53 Activator VIII WRN Helicase Inhibitor inhibit,MDM-2/p53,MIRA1,Apoptosis,NSC-19630,Inhibitor,H1299,MIRA-1,SKOV,NSC19630,Anticancer,MIRA 1,Saos-2 (2,5-dioxopyrrol-1-yl)methyl propanoate 72835-26-8 Apoptosis Inducers