5-Amino-3-phenyl-1,2,4-thiadiazole
- CAS No.
- 17467-15-1
- Chemical Name:
- 5-Amino-3-phenyl-1,2,4-thiadiazole
- Synonyms
- NSC 119930;TIMTEC-BB SBB005511;2-methyl-2-oxolanamine;4-thiadiazol-5-amine,3-phenyl-2;3-Phenyl-1,2,4-triazol-5-ylamine;3-PHENYL-1,2,4-THIADIAZOL-5-AMINE;5-Amino-3-phenyl-1,2,4-thidiazole;5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE;5-Amino-3-plenyl-1,2,4-thiadiazole;2-amino-4-phenyl-1,3,5-thiadiazole
- CBNumber:
- CB9253759
- Molecular Formula:
- C8H7N3S
- Molecular Weight:
- 177.23
- MOL File:
- 17467-15-1.mol
- Modify Date:
- 2024/5/29 15:30:41
Melting point | 152-156 °C |
---|---|
Density | 1.2353 (rough estimate) |
refractive index | 1.5700 (estimate) |
storage temp. | 2-8°C |
form | powder |
color | White |
InChI | InChI=1S/C8H7N3S/c9-8-10-7(11-12-8)6-4-2-1-3-5-6/h1-5H,(H2,9,10,11) |
InChIKey | OYAHSBDYBOBAAQ-UHFFFAOYSA-N |
SMILES | S1C(N)=NC(C2=CC=CC=C2)=N1 |
CAS DataBase Reference | 17467-15-1(CAS DataBase Reference) |
EPA Substance Registry System | 1,2,4-Thiadiazol-5-amine, 3-phenyl- (17467-15-1) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 |
Hazard Codes | Xn,Xi |
Risk Statements | 36/37/38-20/21/22-41-22 |
Safety Statements | 36/37/39-26-22 |
HazardClass | IRRITANT |
HS Code | 29341000 |
5-Amino-3-phenyl-1,2,4-thiadiazole Chemical Properties,Uses,Production
Description
5-Amino-3-phenyl-1,2,4-thiadiazole is an important organic synthetic reagent with remarkable reactivity and stability and has been used in the synthesis of a variety of heterocyclic compounds including 1,2,4-triazol-3-ylphenyls, derivatives of 2-aryl-5-amino-thiadiazole, 5-amino-1,2,4-thiadiazol-3-phenyls, and 5 -amino-1,2,4-thiadiazole-3-phenyl-3-methyl derivatives. It is also used in the synthesis of polymers such as poly(5-amino-3-phenyl-1,2,4-thiadiazole). In addition, 5-amino-3-phenyl-1,2,4-thiadiazole is an inhibitor of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX). The compound inhibits the release of pro-inflammatory cytokines such as tumour necrosis factor-α (TNF-α) and interleukin-1β (IL-1β).
Chemical Properties
LIGHT BROWNISH FINE CRYSTALLINE POWDER
Uses
3-Phenyl-1,2,4-thiadiazol-5-amine is used as a reactant in the preparation of thiazole and thiadiazole derivatives as potent and selective human adenosine A3 receptor antagonists.
5-Amino-3-phenyl-1,2,4-thiadiazole Preparation Products And Raw materials
Raw materials
Preparation Products
5-Amino-3-phenyl-1,2,4-thiadiazole Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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VGS SYNTHESIS PRIVATE LIMITED | +91-9866975588 +91-9866975588 | Hyderabad, India | 1818 | 58 | Inquiry |
INNOVIR BIO SCIENCES PVT LTD | +91-9542235312 +91-9542235312 | Hyderabad, India | 56 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD | +8618291886785 | China | 164 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49392 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29824 | 58 | Inquiry |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | China | 34571 | 58 | Inquiry |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
PT CHEM GROUP LIMITED | China | 35426 | 58 | Inquiry | |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | China | 50003 | 58 | Inquiry |
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