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JNJ 1661010

CAS No.: 681136-29-8

Chemical Name:: JNJ 1661010

Synonyms: 1-Piperazinecarboxamide, N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-;CS-1527;Takeda-25;JNJ 1661010;JNJ 1661010, >=98%;JNJ 1661010 USP/EP/BP;TAKEDA-25;JNJ-1661010;JNJ 1661010;N-Phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide;N-Phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1-piperazinecarboxamide;broad-spectrum,acid,inhibit,hydrolase,barrier,JNJ-1661010,FAAH,Takeda25,Fatty acid amide hydrolase,amide,Takeda 25,blood-brain,Inhibitor,analgesics,Fatty

CBNumber:: CB92457306

Molecular Formula:: C19H19N5OS

Molecular Weight:: 365.45

MOL File:: 681136-29-8.mol

Modify Date:: 2023/6/30 15:45:59

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JNJ 1661010 Properties

Density	1.340±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	DMSO: ≥28mg/mL
form	solid
pka	13.94±0.70(Predicted)
color	Off-white
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS02,GHS07
Signal word	Danger
Hazard statements	H225-H315-H319-H335
Precautionary statements	P210-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P370+P378-P403+P233-P403+P235-P405-P501
WGK Germany	1

JNJ 1661010 Chemical Properties,Uses,Production

Uses

JNJ-1661010, is used to examine the contribution of endocannabinoid signaling in experimental fibrosis. In biological studies, this compound had shown to elevate the levels of arachidonoyl ethanolamide (AEA) in rat brains.

Biological Activity

Selective, reversible inhibitor of fatty acid amide hydrolase (FAAH) (IC 50 = 12nM). Brain penetrant and active in vivo .

JNJ 1661010 Preparation Products And Raw materials

Raw materials

3-PHENYL-5-PIPERAZINO-1,2,4-THIADIAZOLE Phenylboronic acid Phenyl isocyanate

Preparation Products

JNJ 1661010 Suppliers

Global( 72)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	24639	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry
Amadis Chemical Company Limited	571-89925085	China	131980	58	Inquiry
Angel Pharmatech, Ltd.	17317130613	China	3249	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
CLEARSYNTH LABS LTD.	58
CHEMSWORTH	30
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
Dideu Industries Group Limited	58
InvivoChem	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Angel Pharmatech, Ltd.	58

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5-AMINO-3-METHYL-1,2,4-THIADIAZOLE 3-PHENYL-5-PIPERAZINO-1,2,4-THIADIAZOLE JNJ 1661010 5-Amino-1,2,4-thiadiazole 5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE

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JNJ 1661010 N-Phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1-piperazinecarboxamide Takeda-25 JNJ 1661010, >=98% CS-1527 N-Phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide TAKEDA-25;JNJ-1661010;JNJ 1661010 JNJ 1661010 USP/EP/BP 1-Piperazinecarboxamide, N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)- broad-spectrum,acid,inhibit,hydrolase,barrier,JNJ-1661010,FAAH,Takeda25,Fatty acid amide hydrolase,amide,Takeda 25,blood-brain,Inhibitor,analgesics,Fatty 681136-29-8 Inhibitors Inhibitor