SuMatriptan N-Oxide

SuMatriptan N-Oxide Structure
CAS No.
212069-94-8
Chemical Name:
SuMatriptan N-Oxide
Synonyms
GR 112504;Sumatriptan N-Oxide;Penehyclidine Impurity 13;SuMatriptan EP IMpurity D;Sumatriptan N-Oxide (92 %);Sumatriptan Succinate EP impurity D;SuMatriptan Succinate IMpurity – D (EP/BP);Sumatriptan EP Impurity D (Sumatriptan N-Oxide);Sumatriptan Impurity 4(Sumatriptan EP Impurity D);Sumatriptan N-Oxide (Sumatriptan Succinate EP Impurity D)
CBNumber:
CB92551318
Molecular Formula:
C14H21N3O3S
Molecular Weight:
311.4
MOL File:
212069-94-8.mol
MSDS File:
SDS
Modify Date:
2023/5/4 15:12:45

SuMatriptan N-Oxide Properties

Melting point 190-193 °C(Solv: acetone (67-64-1))
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Very Slightly, Heated), Methanol (Very Slightly, Heated), Water (Slightly)
form Solid
pka 11.28±0.40(Predicted)
color Pale Beige to Light Brown
Stability Hygroscopic, Unstable in DMSO

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H318
Precautionary statements  P280-P305+P351+P338-P310

SuMatriptan N-Oxide Chemical Properties,Uses,Production

Uses

Sumatriptan N-Oxide (Sumatriptan EP Impurity D) is the degradation product of the antimigraine drug Sumatriptan (S810000).

SuMatriptan N-Oxide Preparation Products And Raw materials

Raw materials

Preparation Products

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3-[2-(DiMethyloxidoaMino)ethyl]-N-Methyl-1H-indole-5-MethanesulfonaMide GR 112504 SuMatriptan Succinate IMpurity – D (EP/BP) SuMatriptan EP IMpurity D N,N-Dimethyl-2-[5-[(methylsulphamoyl)methyl]-1H-indol-3-yl] ethanamine N-oxide Sumatriptan Impurity 4(Sumatriptan EP Impurity D) Sumatriptan N-Oxide (Sumatriptan Succinate EP Impurity D) 1H-Indole-5-methanesulfonamide, 3-[2-(dimethyloxidoamino)ethyl]-N-methyl- Penehyclidine Impurity 13 Sumatriptan Succinate EP impurity D Sumatriptan N-Oxide (92 %) Sumatriptan EP Impurity D (Sumatriptan N-Oxide) N,N-Dimethyl-2-(5-((N-methylsulfamoyl)methyl)-1H-indol-3-yl)ethanamine oxide (Sumatriptan Impurity) Sumatriptan N-Oxide 212069-94-8 Amines Aromatics Heteroycles Impurities Indole Derivatives Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds