Sumatriptan succinate
- CAS No.
- 103628-48-4
- Chemical Name:
- Sumatriptan succinate
- Synonyms
- SuMitrex;gr43175c;Sumatriptan succinat;Sumatriptan succinate;methanesulfonamide(1:1);SumatriptanSuccinate>Penehyclidine Impurity 9;SUMATRIPTANSUCCINATE(1:1);SuMatriptan Succinate, EP;Sumatriptan succinate CRS
- CBNumber:
- CB1135040
- Molecular Formula:
- C18H27N3O6S
- Molecular Weight:
- 413.48848
- MOL File:
- 103628-48-4.mol
- Modify Date:
- 2025/1/27 9:38:02
| Melting point | 165-166°C |
|---|---|
| storage temp. | -20°C |
| solubility | H2O: >20mg/mL |
| form | solid |
| color | white to off-white |
| Merck | 14,8997 |
| BCS Class | 3 |
| InChIKey | PORMUFZNYQJOEI-UHFFFAOYSA-N |
| CAS DataBase Reference | 103628-48-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H361d-H412 | |||||||||
| Precautionary statements | P202-P273-P280-P308+P313-P405-P501 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-41 | |||||||||
| Safety Statements | 26-36-39 | |||||||||
| RIDADR | 3077 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | EJ9940000 | |||||||||
| HS Code | 29350090 | |||||||||
| NFPA 704 |
|
Sumatriptan succinate price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | S1198 | Sumatriptan succinate ≥98% (HPLC), solid | 103628-48-4 | 10MG | ₹11160.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S1198 | Sumatriptan succinate ≥98% (HPLC), solid | 103628-48-4 | 50MG | ₹44588.18 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR2580 | Sumatriptan Succinate pharmaceutical secondary standard, certified reference material | 103628-48-4 | 500MG | ₹27950.15 | 2022-06-14 | Buy |
| TCI Chemicals (India) | S0851 | Sumatriptan Succinate | 103628-48-4 | 100MG | ₹7900 | 2022-05-26 | Buy |
| TCI Chemicals (India) | S0851 | Sumatriptan Succinate | 103628-48-4 | 1G | ₹14500 | 2022-05-26 | Buy |
Sumatriptan succinate Chemical Properties,Uses,Production
Description
Sumatriptan succinate is a highly selective 5HT1-like receptor agonist introduced as a new treatment for migraine. It is indicated for the acute relief of migraine and cluster headache. Oral administration is reported to be free of substantial side effects. The compound appears to be a significant advance over the use of ergotamine and other agents in the treatment of migraine.
Chemical Properties
White Crystalline Powder
Uses
Sumatriptan Succinate is a selective 5-HT1B/1D-receptor agonist with anticonvulsant properties (1,2). Sumatriptan Succinate is used for migraine relief (2).
Definition
ChEBI: A succinate salt obtained by reaction of sumatriptan with one equivalent of succinic acid. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used for the acute treatm nt of migraine with or without aura in adults.
World Health Organization (WHO)
Suprofen, a nonsteroidal anti-inflammatory agent, was introduced in 1983 for use as an analgesic for the symptomatic relief of mild to moderate pain and for primary dysmenorrhoea. By 1986 it had become evident that its use was occasionally associated with flank pain sometimes accompanied by evidence of decreased renal function. The Arthritis Advisory Committee of the United States Food and Drug Administration met in December 1986 to review the situation and decided against withdrawing suprofen from the market. However, in May 1987 the Committee for Proprietary Medicinal Products of the European Community recommended that all marketing authorizations should be suspended. The manufacturer subsequently decided to suspend sale worldwide on the grounds that sales had diminished to the point where the product was no longer economically viable.
Biological Activity
Selective 5-HT 1 receptor agonist (K i values are 17, 27 and 100 nM at 5-HT 1D , 5-HT 1B and 5-HT 1A receptors respectively). Antimigraine agent.
Sumatriptan succinate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Urantiis Pharmaceuticals Private Limited | +918790703567 | AndhraPradesh, India | 80 | 58 | Inquiry |
| Dr. Reddy's Laboratories Ltd | +91-4049002900 +91-4049002900 | Hyderabad, India | 165 | 58 | Inquiry |
| AnalyticsStanza Inc | +91-7032031309 +91-7032031309 | Hyderabad, India | 226 | 58 | Inquiry |
| AARTIA KEM SCIENCE | +91-8291072530 +91-8291072530 | Maharashtra, India | 70 | 58 | Inquiry |
| Sun Pharmaceutical Industries Ltd | +91-2242244224 +91-2243244324 | Maharashtra, India | 108 | 58 | Inquiry |
| Nosch Labs Pvt Ltd | +91-4048557474 +91-9948222287 | Hyderabad, India | 58 | 58 | Inquiry |
| Orchid Pharma Ltd. (Formerly Known as Orchid Chemicals and Pharmaceuticals Ltd.) | +91-4428244254 +91-4428244254 | Tamil Nadu, India | 28 | 58 | Inquiry |
| Smilax Laboratories Limited | +91-8919514965 +91-8008333438 | Telangana, India | 28 | 58 | Inquiry |
| HRV Global Life Sciences | +91-9820219686 +91-9820219686 | Telangana, India | 379 | 58 | Inquiry |
| Lakshmi Farmachem | +91-9948795885 +91-9550886476 | Telangana, India | 407 | 58 | Inquiry |
103628-48-4(Sumatriptan succinate)Related Search:
1of4
chevron_right