Rizatriptan

Rizatriptan Structure
CAS No.
144034-80-0
Chemical Name:
Rizatriptan
Synonyms
CS-281;RIZATRIPTAN;Rizatriptan-d3;Rizatriptan USP/EP/BP;Rizatriptan###144034-80-0;2-(5-((1H-1,2,4-Triazol-1-yl);Acetochlor Impurity 3 (Butachlor);N,N-Dimethyl-5-(1H-1,2,4-trizol-1-ylmethyl)-1H-indole-3-ethanamine;n,n-dimethyl-5-(1h-1,2,4-triazol-1-ylmethyl)-1h-indole-3-ethanamine;1H-Indole-3-ethanaMine,N,N-diMethyl-5-(1H-1,2,4-triazol-1-ylMethyl)-
CBNumber:
CB3245026
Molecular Formula:
C15H19N5
Molecular Weight:
269.34
MOL File:
144034-80-0.mol
MSDS File:
SDS
Modify Date:
2024/5/13 20:55:28

Rizatriptan Properties

Melting point 178-180°C
Boiling point 504.8±60.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 16.98±0.30(Predicted)
Water Solubility 42 mg/mL
CAS DataBase Reference 144034-80-0(CAS DataBase Reference)
EPA Substance Registry System Acetonitrile, 2,2-dibromo-2-chloro- (144034-80-0)

SAFETY

Risk and Safety Statements

Rizatriptan Chemical Properties,Uses,Production

Uses

Rizatriptan is reported to be a very effective acute migraine drug. It is reported to display high agonist activity at mainly the serotonin 5-HT1B and 5-HT1D receptor subtypes.

brand name

Maxalt (Merck).

General Description

Rizatriptan, approved in 1998, is a fast-acting triptan becauseof its moderate lipophilicity yet has a very shortelimination half-life similar to sumatriptan (i.e., like sumatriptan,it is mainly metabolized by MAO-A). The only advantagesof this drug when compared with sumatriptan arethat it has a slightly faster onset and that it has an orallydisintegrating tablet formulation which can be taken withoutwater.

Rizatriptan Preparation Products And Raw materials

Raw materials

Preparation Products

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n,n-dimethyl-5-(1h-1,2,4-triazol-1-ylmethyl)-1h-indole-3-ethanamine n,n-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1h-indol-3-yl]ethanamine RIZATRIPTAN diMethyl({2-[5-(1H-1,2,4-triazol-1-ylMethyl)-1H-indol-3-yl]ethyl})aMine 2-(5-((1H-1,2,4-Triazol-1-yl)Methyl)-1H-indol-3-yl)-N,N-diMethylethanaMine 1H-Indole-3-ethanaMine,N,N-diMethyl-5-(1H-1,2,4-triazol-1-ylMethyl)- Rizatriptan###144034-80-0 2-(5-((1H-1,2,4-Triazol-1-yl) CS-281 Rizatriptan USP/EP/BP N,N-Dimethyl-5-(1H-1,2,4-trizol-1-ylmethyl)-1H-indole-3-ethanamine RizatriptanQ: What is Rizatriptan Q: What is the CAS Number of Rizatriptan Q: What is the storage condition of Rizatriptan Q: What are the applications of Rizatriptan Rizatriptan-d3 Acetochlor Impurity 3 (Butachlor) 144034-80-0 NORVASC Other APIs