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p-Toluenesulfonamide

p-Toluenesulfonamide  Structure
CAS No.
70-55-3
Chemical Name:
p-Toluenesulfonamide
Synonyms
PTSA;4-METHYLBENZENESULFONAMIDE;Tosylamide;Tosylamine;4-TOLUENESULFONAMIDE;P-TOLUENESULPHONAMIDE;TOLUENE-4-SULFONAMIDE;p-Tosylamide;p-Toluenesulfoamide;P-TOLUENESULFONYLAMIDE
CBNumber:
CB7330843
Molecular Formula:
C7H9NO2S
Molecular Weight:
171.22
MOL File:
70-55-3.mol
MSDS File:
SDS
Modify Date:
2024/8/14 11:55:41

p-Toluenesulfonamide Properties

Melting point 134-137 °C (lit.)
Boiling point 221 °C (10 mmHg)
Density 1.2495 (rough estimate)
vapor density 5.9 (vs air)
refractive index 1.6100 (estimate)
Flash point 202 °C
storage temp. Store below +30°C.
solubility DMSO: soluble
form Crystalline Powder
pka 10.20±0.10(Predicted)
color White
Odor Odorless
Water Solubility 0.32 g/100 mL (25 º C)
BRN 472689
LogP 0.820
CAS DataBase Reference 70-55-3(CAS DataBase Reference)
NIST Chemistry Reference 4-Methylbenzenesulfonamide(70-55-3)
EPA Substance Registry System p-Toluenesulfonamide (70-55-3)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi,Xn
Risk Statements  36-20/21/22
Safety Statements  26-36
WGK Germany  1
RTECS  XT5075000
TSCA  Yes
PackingGroup  III
HS Code  29350090
NFPA 704
0
2 0

p-Toluenesulfonamide price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 8.08230 4-Toluenesulfonamide for synthesis 70-55-3 100G ₹5600 2022-06-14 Buy
Sigma-Aldrich(India) 8.08230 4-Toluenesulfonamide for synthesis 70-55-3 1KG ₹5880 2022-06-14 Buy
Sigma-Aldrich(India) PHR1474 p-Toluenesulfonamide Pharmaceutical Secondary Standard; Certified Reference Material 70-55-3 500MG ₹12080.7 2022-06-14 Buy
Sigma-Aldrich(India) 8.08230 4-Toluenesulfonamide for synthesis 70-55-3 25KG ₹42800.01 2022-06-14 Buy
Sigma-Aldrich(India) 236330 p-Toluenesulfonamide ReagentPlus?, ≥99% 70-55-3 10G ₹3312.45 2022-06-14 Buy
Product number Packaging Price Buy
8.08230 100G ₹5600 Buy
8.08230 1KG ₹5880 Buy
PHR1474 500MG ₹12080.7 Buy
8.08230 25KG ₹42800.01 Buy
236330 10G ₹3312.45 Buy

p-Toluenesulfonamide Chemical Properties,Uses,Production

Chemical Properties

White leaflets. Soluble in alcohol; very slightly soluble inwater.Combustible.

Uses

p-Toluenesulfonamide was used to prepare the precursor required for synthesis of ethyl 6-phenyl-1-tosyl-1,2,5,6-tetrahydropyridine-3-carboxylate.

Definition

ChEBI: A sulfonamide that is benzenesulfonamide bearing a methyl group at position 4.

General Description

p-Toluenesulfonamide undergoes FeCl3-catalyzed direct substitution reaction with benzylic and allylic alcohols.It is employed as nucleophile in tetrabutylammonium fluoride (TBAF) catalyzed vinyl aziridine opening reaction.

Purification Methods

Crystallise the amide from hot water, then from EtOH or Et2O/pet ether. [Beilstein 11 H 104, 11 IV 376.]

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Uniplex 173 4-TOLUENESULFONIC ACID AMIDE P-TOLUENESULFONAMIDE PASAM TOLUENE-4-SULPHONAMIDE Ortho Para-Toluene Sulfonamide/Mixed O/PTSA o-Toluenesulphonamide(OTSA) p-Toluenesulphonamide/Para-Toluene Sulfonamide(PTSA) 4-Toluenesulphonamide P-TOLUENESULFONAMIDE, 99+% Para toluene sulfonate p-ToluenesulfonaMide reagent grade, 98% p-ToluenesulfonaMide ReagentPlus(R), >=99% p-ToluenesulfonaMide, AR,98% p-Toluenesulfonamide p-Toluenesulfonamide Vetec(TM) reagent grade, 98% p-Toluenesulfo p-Toluenesulfomide 4-methyl-benzenesulfonamid 4-Toluenesulfanamide Benzenesulfonamide, 4-methyl- P-Toluenesulphonamide>98% PTolueneSulfonicAmide 4-Toluenesulfonamide99% P-TolueneSulfonAmide(Ptsa)99% p-Toluenesulfonamide, 98+% P-Toluene Sulfon Amide(Ptsa) 99% Benzenesulfonamide, 4-methyl- (9CI) p-toluene suplhonamide PARATOLUENESULFONICAMIDE P-Toluenesulfonylamine PARA-TOLUENESULPHONAMIDE p-Toluolsulfonamid p-Toluenesulfonamide (200 mg) 4-Methylbenzene-1-sulfonaMide p-ToluenesulfonaMide, 99% 250GR IMp. A (EP): (4-Methylphenyl)sulfonaMide(ToluenesulfonaMide 4-TOLUENESULFONAMIDE FOR SYNTHESIS Benzenesulfonamide,4-methyl- para-toluenesulfamine para-Toluenesulfonamide p-Methylbenzenesulfonamide p-Toluenesulfamide p-Toluenesulfanamide p-Tolylsulfonamide Tolouen-4-sulfonamid Tolouen-4-sulfonamide Toluene-p-sulfonamide Toluene-p-sulphonamide Tolylsulfonamide 4-Tolylsulfonamide Gliclazide EP Impurity A (Saccharin Impurity) Gliclazide EP impurity A -G Gliclazide EP impurity A Gliclazide Impurity 1(Gliclazide EP Impurity A) p-Toluenesulfonamideamidelfonamide 4-Methylbenzenesulphonamide p-Toluenesulfonamide >