ChemicalBook > Product Catalog >API >Hormones and the Endocrine System >Pancreatic hormone and blood sugar regulation >Gliclazide
Gliclazide
- CAS No.
- 21187-98-4
- Chemical Name:
- Gliclazide
- Synonyms
- GLIMICRON;1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea;Gliclazide analogue: N-[[(Hexahydrocyclopenta [c]pyrrol-2(1H)-yl)aMino]carbonyl]-2-Methyl benzenesulfonaMide;s852;se1702;S-1702;Diaprel;Glyzide;DIAMICRON;Glinormax
- CBNumber:
- CB5113462
- Molecular Formula:
- C15H21N3O3S
- Molecular Weight:
- 323.41
- MOL File:
- 21187-98-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/23 18:28:04
| Melting point | 163-169 °C (lit.) |
|---|---|
| Density | 1.2205 (rough estimate) |
| refractive index | 1.6740 (estimate) |
| storage temp. | 2-8°C |
| solubility | methylene chloride: soluble |
| form | powder |
| pka | 6.07±0.10(Predicted) |
| color | white |
| Merck | 14,4439 |
| InChI | InChI=1S/C15H21N3O3S/c1-11-5-7-14(8-6-11)22(20,21)17-15(19)16-18-9-12-3-2-4-13(12)10-18/h5-8,12-13H,2-4,9-10H2,1H3,(H2,16,17,19) |
| InChIKey | BOVGTQGAOIONJV-UHFFFAOYSA-N |
| SMILES | C1(S(NC(NN2CC3CCCC3C2)=O)(=O)=O)=CC=C(C)C=C1 |
| CAS DataBase Reference | 21187-98-4(CAS DataBase Reference) |
| EPA Substance Registry System | Benzenesulfonamide, N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl (21187-98-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 21-36/38-46-62-63 | |||||||||
| Safety Statements | 25-26-36/37-53-24/25 | |||||||||
| RIDADR | 3077 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | YT4500000 | |||||||||
| HS Code | 29350090 | |||||||||
| Toxicity | LD50 orally in mice: >3 g/kg (Duhault) | |||||||||
| NFPA 704 |
|
Gliclazide price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PHR1288 | Gliclazide Pharmaceutical Secondary Standard; Certified Reference Material | 21187-98-4 | 1G | ₹7382.65 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G2167 | Gliclazide powder, ≥98% | 21187-98-4 | 5G | ₹15468.93 | 2022-06-14 | Buy |
| TCI Chemicals (India) | G0381 | Gliclazide | 21187-98-4 | 5G | ₹7500 | 2022-05-26 | Buy |
Gliclazide Chemical Properties,Uses,Production
Chemical Properties
White Cyrstalline Solid
General Description
Chemically, gliclazide, 1-(3-azabicyclo[3.3.0]oct-3-yl)-3-p-tolylsulphonylurea (Diamicron), isvery similar to tolbutamide, with the exception of the bicyclicheterocyclic ring found in gliclazide. The pyrrolidineincreases its lipophilicity over that of tolbutamide,which increases its half-life. Even so, the p-methyl is susceptibleto the same oxidative metabolic fate as observedfor tolbutamide, namely, it will be metabolized to a carboxylicacid.
Gliclazide Preparation Products And Raw materials
Raw materials
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Global( 634)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Reliance Rasayan Pvt Ltd | +91-9427160241 +91-9427160241 | Gujarat, India | 21 | 58 | Inquiry |
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| Organo Chem (India) | +91-8459110412 +91-9810846377 | Uttar Pradesh, India | 21 | 58 | Inquiry |
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| Medi Pharma Drug House | +919930911911 | Mumbai, India | 143 | 58 | Inquiry |
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21187-98-4(Gliclazide)Related Search:
Gliclazide iMpurity D
octahydro-2-nitrosocyclopenta[c]pyrrole
N-[[(HEXAHYDROCYCLOPENTA [C]PYRROL-2(1H)-YL)AMINO]CARBONYL]-2-METHYL BENZENESULFONAMIDE
Gliclazide EP Impurity G
Gliclazide Impurity (Methyl N-Methyl-p-Tolysulphoncarbomate)
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Gliclazide, BP
)-4-methyl-
1-(hexahydrocyclopenta(c)pyrrol-2(1h)-yl)-3-(p-tolylsulfonyl)-ure
1-(hexahydrocyclopenta(c)pyrrol-2(1h)-yl)-3-(p-tolylsulfonyl)urea
benzenesulfonamide,n-(((hexahydrocyclopenta(c)pyrrol-2(1h)-yl)amino)carbonyl
n-(4-methylbenzenesulfonyl)-n’-(3-azabicyclo(3.3.0)oct-3-yl)urea
Tetrabenzyl Voglibose HCl
1-[3-Azabicyclo[3.3.0]oct-3-yl]-3-p-toluenesulfonylurea
3-[(3aR,6aS)-octahydrocyclopenta[c]pyrrol-2-yl]-1-[(4-Methylbenzene)sulfonyl]urea
Tetrabenzyl Cycloketone ("TBC")
Methyl N-Methyl-p-tolylsulphoncarbaMate
etrabenzyl Voglibose HCl
TBC Tetrabenzyl Cycloketone
TBG Voglibose TBG Impurity
TBV HCl Tetrabenzyl Voglibose HCl
Gliclazide Impurity Ⅰ
BENZENESULFONAMIDE, N-[[(HEXAHYDROCYCLOPENTA[C]PYRROL-2(1H)-YL)AMINO]CARBONYL]-4-METHYL-
GLICLAZIDE
DIAMICRON
Gliclazide, >=99%
s852
se1702
1-[Hexahydrocylopenta [c] pyrrol-2[1H]-yl]-3-[p-tolylsulfonyl] urea
Cyclopenta[c]pyrrole, benzenesulfonamide deriv.
Diabezidum
Diabrezide
Diaprel
Glinormax
Glyzide
Urea, 1-(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)- (8CI)
GLICLAZIDE B.P. 2000
Gliclazide CP2000 BP98
Glibenclamide CP2000,BP93
Gliclazide BP98
GLUCLAZIDE
3-(7-azabicyclo[3.3.0]oct-7-yl)-1-(4-methylphenyl)sulfonyl-urea
1-(3,3a,4,5,6,6a-Hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea
1-(3-Azabicyclo[3.3.0]octan-3-yl)-3-(4-methylphenylsulfonyl)urea
N-[[(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methylbenzenesulfonamide
Gliclazide,1-(3-Azabicyclo[3.3.0]oct-3-yl)-3-p-tolylsulphonylurea
1-(3-azabicyclo[3.3.0]oct-3-yl)-3-p-tolylsulphonylurea
1-(3-AZABICYGCLO[33.0]OCT-3-YL)-3-O-TOLYLSULPHONYLUREA
AKOS NCG1-0056
N-[[[HEXAHYDROCYLOPENTA[C]PYRROL-2(1H)-YL]AMINO]CARBONYL]-4-METHYLBENZENESULFONAMIDE
NORDIALEX
SALOR-INT L255629-1EA
S-1702
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Gliclazide
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Gliclazide (S1702
Gliclazide (1.0 mg/mL in Methanol)
Gliclazide USP/EP/BP
GliclazideSolution,2000mg/L,4x1ml
Gliclazide CRS
Gliclazide>
Methyl N-methyl-p-tolysulphoncarbomate
Gliclazide, 99%, whole-cell beta-cell ATP-sensitive potassium currents blocker
1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea