4-Hydroxybenzamide
- CAS No.
- 619-57-8
- Chemical Name:
- 4-Hydroxybenzamide
- Synonyms
- 4-HYDROXYBENZAMIDE;P-HYDROXYBENZAMIDE;Benzamide,p-hydroxy-;Benzamide,4-hydroxy-;4-Hydroxybenzamide>4-HYDROXYBENZAMIDE 98%;4-HYDROXYBENZAMIDE, 97+%;4-Hydroxybenzamide, 98+%;4-Hydroxy-benzoesaeure-amid;Benzamide, 4-hydroxy- (9CI)
- CBNumber:
- CB9271791
- Molecular Formula:
- C7H7NO2
- Molecular Weight:
- 137.14
- MOL File:
- 619-57-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/11/1 10:41:54
| Melting point | 161-162 °C (lit.) |
|---|---|
| Boiling point | 345.3±25.0 °C(Predicted) |
| Density | 1.286±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 8.60±0.13(Predicted) |
| color | White to Light yellow to Dark green |
| BRN | 1906921 |
| InChI | InChI=1S/C7H7NO2/c8-7(10)5-1-3-6(9)4-2-5/h1-4,9H,(H2,8,10) |
| InChIKey | QXSAKPUBHTZHKW-UHFFFAOYSA-N |
| SMILES | C(N)(=O)C1=CC=C(O)C=C1 |
| CAS DataBase Reference | 619-57-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29242990 | |||||||||
| NFPA 704 |
|
4-Hydroxybenzamide price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 270253 | 4-Hydroxybenzamide 98% | 619-57-8 | 5G | ₹2002.63 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 270253 | 4-Hydroxybenzamide 98% | 619-57-8 | 25G | ₹11377.08 | 2022-06-14 | Buy |
| TCI Chemicals (India) | H0200 | 4-Hydroxybenzamide | 619-57-8 | 5G | ₹3100 | 2022-05-26 | Buy |
| TCI Chemicals (India) | H0200 | 4-Hydroxybenzamide | 619-57-8 | 25G | ₹8900 | 2022-05-26 | Buy |
| ottokemi | H 1580 | 4-Hydroxy benzamide 98% | 619-57-8 | 5gm | ₹1998 | 2022-05-26 | Buy |
4-Hydroxybenzamide Chemical Properties,Uses,Production
Chemical Properties
White to off-white crystalline powder
Uses
4-Hydroxybenzamide is a secondary metabolite from marine sponge Phakellia fusca.
Definition
4-Hydroxybenzamide (4HBM) is an important biological active compound that has the presence of various biological activities such as antimycobacterial, antifungal, antimicrobial, herbicidal, and antioxidant. The benzamide derivatives are also used in medical, pharmaceutical, and therapeutic applications because of their anti-inflammatory, antibacterial, and antifungal activities. The amine and carboxylic acids are important functional groups of present molecules. These are mainly utilized in the field of chemical industry. The cocrystallization of itraconazole (a very slightly soluble triazole antifungal drug) with 4-hydroxybenzamide (4OHBZA) can potentially increase the drug solubility at pH1.2 and 37 °C by 64 times[1-2].
References
[1] Ramesh P, et al. Theoretical and experimental spectroscopic studies of monomeric and dimeric structures of 4-hydroxybenzamide International Journal of Pharmaceutics. Journal of Molecular Structure, 2020; 1206: 127742.
[2] Vasilev N, et al. Novel cocrystals of itraconazole: Insights from phase diagrams, formation thermodynamics and solubility. International Journal of Pharmaceutics, 2021; 599: 120441.
General Description
The standard molar enthalpy of formation of 4-hydroxybenzamide was studied by micro- or macrocombustion calorimetry.
Source
4-Hydroxybenzamide is a natural product found in Oxytropis falcata, Houttuynia cordata, and Streptomyces tendae with data available.
4-Hydroxybenzamide Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SYNGREEN LIFESCIENCES PVT.LTD | +919849474297 | Telangana, India | 82 | 58 | Inquiry |
| SURVIVAL TECHNOLOGIES LIMITED | +91 8108285261 | Gujarat, India | 294 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| BASR Fine Chemicals Pvt. Ltd. | +91-9848230391 +91-9848230391 | Telangana, India | 908 | 58 | Inquiry |
| Syn Finechem Laboratories Pvt Ltd. | +91-9848230784 +91-9848230784 | Telangana, India | 423 | 58 | Inquiry |
| Basr Fine Chemicals Pvt., Ltd. | 91-40-23090147 | Hyderabad, India | 134 | 58 | Inquiry |
| ALR Fine Chemicals Pvt Ltd | +91-40-2000 0192 | Hyderabad, India | 283 | 58 | Inquiry |
| Spectrochem Private Limited | 08048372608Ext 246 | Maharashtra, India | 1056 | 58 | Inquiry |
| Vignasai Laboratories Pvt., Ltd. | 91-9030998889 | Hyderabad, India | 169 | 58 | Inquiry |
| Oceanic Pharmachem Pvt. Ltd. | 91-22-42128600 | Maharashtra, India | 2006 | 58 | Inquiry |
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