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4-Hydroxythiobenzamide

CAS No.: 25984-63-8

Chemical Name:: 4-Hydroxythiobenzamide

Synonyms: 4-hydroxybenzothioamide;HydroxythiobenzaMide;p-HydroxyThioBenzamide;Febuxostat Intermediate;Benzenecarbothioamide, 4-hydroxy-;Febuxostat-22;4-hydroxy thiobenzam;5-HydroxythiobenzaMide;4-HYDROXYTHIOBENZAMIDE;4-Hydroxythiobenzamied

CBNumber:: CB1314575

Molecular Formula:: C7H7NOS

Molecular Weight:: 153.2

MOL File:: 25984-63-8.mol

MSDS File:: SDS

Modify Date:: 2024/7/11 17:04:31

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4-Hydroxythiobenzamide Properties

Melting point	181-185℃
Boiling point	320.4±44.0 °C(Predicted)
Density	1.338±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	9.24±0.26(Predicted)
color	Light Yellow
InChI	InChI=1S/C7H7NOS/c8-7(10)5-1-3-6(9)4-2-5/h1-4,9H,(H2,8,10)
InChIKey	VDTNKXSVUGXUOJ-UHFFFAOYSA-N
SMILES	C1(C(N)=S)=CC=C(O)C=C1
CAS DataBase Reference	25984-63-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H302-H335

Precautionary statements

P280h-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Hazard Codes

Risk Statements

20/21/22-36/37/38-43-22

Safety Statements

26-36/37/39-36/37

HS Code

29242990

NFPA 704

	1
2		0

4-Hydroxythiobenzamide price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemicals (India)	H1308	4-Hydroxythiobenzamide	25984-63-8	5G	₹5000	2022-05-26	Buy
TCI Chemicals (India)	H1308	4-Hydroxythiobenzamide	25984-63-8	25G	₹15900	2022-05-26	Buy

Product number	Packaging	Price	Buy
H1308	5G	₹5000	Buy
H1308	25G	₹15900	Buy

4-Hydroxythiobenzamide Chemical Properties,Uses,Production

Chemical Properties

4-Hydroxythiobenzamide has an appearance ranging from light orange to yellow to green, powder to crystalline, melting point 192 °C, soluble in methanol.

Uses

4-Hydroxythiobenzamide is used in the synthesis of PPARα agonists used in increasing HDLc levels. Also used in the synthesis of potent CDK5 inhibitors in the treatment of Alzheimer’s disease.

Synthesis

4-Hydroxythiobenzamide is an important intermediate of Febuxostat, a new anti-gout drug. A patent discloses a method for preparing p-hydroxythiobenzamide. Specifically, a certain amount of water, p-cyanophenol, sodium hydrosulfide, and secondary amine are mixed evenly. At a specific temperature, an organic weak acid is added dropwise. After the reaction is completed, the mixture is filtered, and the filter cake is dried to obtain 4-Hydroxythiobenzamide.

4-Hydroxythiobenzamide Preparation Products And Raw materials

Raw materials

4-Hydroxybenzamide 4-Cyanophenol

Preparation Products

4-Hydroxythiobenzamide Suppliers

Global( 539)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
BTC pharm India	+918790379245	AndhraPradesh, India	1269	58	Inquiry
MOLECRAFT LIFE SCIENCES PVT LTD	+91 9581188881	Telangana, India	189	58	Inquiry
Ralington Pharma	+91-7948911722 +91-9687771722	Gujarat, India	1350	58	Inquiry
VGS SYNTHESIS PRIVATE LIMITED	+91-9866975588 +91-9866975588	Hyderabad, India	1818	58	Inquiry
Enal Drugs Pvt Ltd	+914044753636	Telangana, India	35	58	Inquiry
Prodev Pharma Pvt Ltd	+91-9963029529 +91-9043422844	Telangana, India	102	58	Inquiry
Samruddhi Agro and Lifescience	+91-9923605583 +91-7028045583	Ahmedabad, India	8	58	Inquiry
Apiqule Pharmachem LLP	+91-9537957857 +91-9904897541	Gujarat, India	21	58	Inquiry
Rivashaa Agrotech Biopharma Pvt. Ltd.	+91-26463395 +91-7926462688	Gujarat, India	1615	58	Inquiry
Manus Aktteva Biopharma LLP	08048250218Ext 800	Ahmedabad, India	655	58	Inquiry

Supplier	Advantage
BTC pharm India	58
MOLECRAFT LIFE SCIENCES PVT LTD	58
Ralington Pharma	58
VGS SYNTHESIS PRIVATE LIMITED	58
Enal Drugs Pvt Ltd	58
Prodev Pharma Pvt Ltd	58
Samruddhi Agro and Lifescience	58
Apiqule Pharmachem LLP	58
Rivashaa Agrotech Biopharma Pvt. Ltd.	58
Manus Aktteva Biopharma LLP	58

25984-63-8(4-Hydroxythiobenzamide)Related Search:

ethyl 2-(4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate ETHYL 2-(3-FORMYL-4-ISOBUTOXYPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLATE ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate Febuxostat 4-HYDROXYTHIOBENZAMIDE

4-METHOXYTHIOBENZAMIDE 2,3-DIHYDRO-1,4-BENZODIOXINE-6-CARBOTHIOAMIDE 6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE-1-THIONE Tritiozine Vanitiolide

4-Ethoxybenzenecarbothioamide Benzamide THIOBENZAMIDE 4-[5-(TRIFLUOROMETHYL)PYRID-2-YLOXY]THIOBENZAMIDE 4-METHOXY-3-NITROBENZENE-1-CARBOTHIOAMIDE

2,3-DIHYDROBENZO[B]FURAN-5-CARBOTHIOAMIDE 1,3-BENZODIOXOLE-5-CARBOTHIOAMIDE 1-BENZYL-3-(TERT-BUTYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID

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4-HYDROXYTHIOBENZAMIDE 4-HYDROXY THIOBENZAMIDE 98.0%MIN 4-Hydroxy Thiobenzamide p-Hydroxy Thiobenzamide 4-Hydroxybenzene-1-carbothioamide 4-hydroxy thiobenzam 4-HYDROXYTHIOBENZAMIDE 4-Hydroxy ThiobenzaMide p-Hydroxy ThiobenzaMide p-HydroxyThioBenzaMide 4-hydroxybenzothioaMide 5-HydroxythiobenzaMide 4-[amino(sulfanyl)methylidene]cyclohexa-2,5-dien-1-one Febuxostat-22 4-Hydroxythiobenzamide 4-Hydroxybenzene-1-carbothioamide 4-Hydroxythiobenzamide> Febuxostat intermediates，4-Hydroxythiobenzamide 4-Hydroxythiobenzamide CAS 25984-63-8 4-Hydroxythiobenzamied 4-hydroxy-3-nitrobenzenecarbothioamide Febuxostat Intermediate HydroxythiobenzaMide 4-hydroxybenzothioamide p-HydroxyThioBenzamide Benzenecarbothioamide, 4-hydroxy- 4-Hydroxythiobenzamide 25984-63-8 Pharmaceutical Intermediates ,Pharmaceutical Raw Material 1/4-hydroxythiobenzamide, an intermediate of fepristone 4-Hydroxythiobenzamide (F1) 25984-63-8 256984-63-8 29584-63-8 C7H8NOS C7H7NOS Febuxostat Intermediates Febuxostat intermediate chemical additive pharmaceutical intermediate 25984-63-8