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Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate

CAS No.: 161798-01-2

Chemical Name:: Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate

Synonyms: ETHYL 2-(3-FORMYL-4-HYDROXYPHENYL)-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE;Febuxostat-23;Febuxostat PI-2;-4-hydroxyphenyL;Febuxostat Impurity 1;Febuxostat Impurities1;Febuxostat Impurity Z17;Febuxostat intermediate3;Ethyl 2-(3-formyl-4-hydroxyphenyl);5-carboxylato-1-ethyl-2-(3-forMyl-4-h

CBNumber:: CB12128604

Molecular Formula:: C14H13NO4S

Molecular Weight:: 291.32

MOL File:: 161798-01-2.mol

Modify Date:: 2024/8/1 17:24:31

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Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate Properties

Melting point	116 °C
Boiling point	446.7±55.0 °C(Predicted)
Density	1.335
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	6.81±0.20(Predicted)
color	Pale Yellow to Yellow
InChI	InChI=1S/C14H13NO4S/c1-3-19-14(18)12-8(2)15-13(20-12)9-4-5-11(17)10(6-9)7-16/h4-7,17H,3H2,1-2H3
InChIKey	NJRGQNNSIAFIJC-UHFFFAOYSA-N
SMILES	S1C(C(OCC)=O)=C(C)N=C1C1=CC=C(O)C(C=O)=C1
CAS DataBase Reference	161798-01-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H315-H335
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
HS Code	2934100090

Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemicals (India)	E1394	Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate min. 98.0 %	161798-01-2	5G	₹2400	2022-05-26	Buy
TCI Chemicals (India)	E1394	Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate min. 98.0 %	161798-01-2	25G	₹9200	2022-05-26	Buy

Product number	Packaging	Price	Buy
E1394	5G	₹2400	Buy
E1394	25G	₹9200	Buy

Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate Chemical Properties,Uses,Production

Description

Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate is a pharmaceutical intermediate used in the preparation of the xanthine oxidase inhibitor febuxostat, which is used in the treatment of hyperuricaemia and gout. It is also used in the synthesis of novel thiazolyl α-aminophosphonates.

Chemical Properties

Yellow or yellow powder

Uses

Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate is a product prepared via reaction 4-Hydroxybenzene-1-benzothiomide with ethyl-2-chloro acetoacetate. An antibacterial agent and antifungal activity against C.albicans.

Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate Suppliers

Global( 391)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
VASUDHA PHARMA CHEM LIMITED	+91-91-4044763666 +91-9396659284	Telangana, India	102	58	Inquiry
SynThink RESEARCH CHEMICALS	+91-8177860948 +91-8177860948	Mumbai, India	494	58	Inquiry
Viyash Life Sciences Pvt Ltd	+91-4023635052 +91-4023635052	Telangana, India	213	58	Inquiry
Basic Pharma Life Science Pvt Ltd	+919825056886	Gujarat, India	28	58	Inquiry
Everest Organics Limited	+91-4040028838 +91-9440409996	Hyderabad, India	61	58	Inquiry
Lakshmi Farmachem	+91-9948795885 +91-9550886476	Telangana, India	407	58	Inquiry
Chempifine Chemicals	+91-2225667766 +91-2225667766	Punjab, India	144	58	Inquiry
Rivashaa Agrotech Biopharma Pvt. Ltd.	+91-26463395 +91-7926462688	Gujarat, India	1615	58	Inquiry
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Orgamine Chemicals(I) Pvt Ltd	+91-9820080281 +91-9820080281	Maharashtra, India	451	58	Inquiry

Supplier	Advantage
VASUDHA PHARMA CHEM LIMITED	58
SynThink RESEARCH CHEMICALS	58
Viyash Life Sciences Pvt Ltd	58
Basic Pharma Life Science Pvt Ltd	58
Everest Organics Limited	58
Lakshmi Farmachem	58
Chempifine Chemicals	58
Rivashaa Agrotech Biopharma Pvt. Ltd.	58
Ralington Pharma	58
Orgamine Chemicals(I) Pvt Ltd	58

161798-01-2(Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate)Related Search:

Febuxostat Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate isopropyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid 5,5'-DiMethyl Ester Febuxostat Impurity 14

2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid Febuxostat Impurity 6 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid 2-[3-Carboxy-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid 2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid

Febuxostat Impurity 8 4-(2-Methylpropoxy)-1,3-benzenedicarbothioaMide Ethyl 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate 3-Cyano-4-(2-methylpropoxy)benzenecarbothioamide Ethyl 2-(3-bromo-4-isobutoxyphenyl)- 4-methyl-5-thiazolecarboxylate

4-HYDROXYTHIOBENZAMIDE ETHYL 2-(3-FORMYL-4-ISOBUTOXYPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLATE ethyl 2-(4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate

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ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate 2-(3-Formyl-4-hydroxy-phenyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester Thiazolecarboxylicacid,2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-,ethylester 5-carboxylato-1-ethyl-2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-1H-1$l^{4},3-thiazol-1-yl Ethyl 2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-5-Thiazolecarboxylate 5-carboxylato-1-ethyl-2-(3-forMyl-4-h 5-Thiazolecarboxylicacid, 2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-, ethyl ester 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate Febuxostat Impurity 1 Febuxostat PI-2 Ethyl 2-(3-formyl-4-hydroxyphenyl) 2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-5-Thiazolecarboxylicacid ethyl ester Febuxostat-23 Febuxostat intermediate3 ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazo Febuxostat Impurity Z17 ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5- -4-hydroxyphenyL ethyl-2-(3-formyl-4-hydroxyphenyl)-4-methyl thiozole-5-carboxylate Febuxostat intermediates，Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate 2- Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carbox... Febuxostat Impurities1 ETHYL 2-(3-FORMYL-4-HYDROXYPHENYL)-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE Ethyl 2-(3- aldehyde -4- hydroxyphenyl) -4- methylthiazole -5- carboxylate Ethyl 2-(3-formyl-4-hydroxypheip)-4-methylthiazole-5-carboxylate 5-Thiazolecarboxylic acid, 2-(3-formyl-4-hydroxyphenyl)-4-methyl-, ethyl ester (9CI, ACI) 2-(3-formyl-4-hydroxyphenyl)-4-methyl-5-Thiazolecarboxylic acid ethyl ester (9CI ACI) 2-(3-formyl-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate（F3） Ethyl 2-(3-formyl-4- hydroxyphenyl)-4- 2-(3-formyl-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylat 2- (3-aldehyde 4-hydroxyphenyl) -4-methylthiazole-5-carboxylic acid ethyl ester 161798-01-2 Febuxostat intermediate 161798-01-2