AMBROX DL
- CAS No.
- 3738-00-9
- Chemical Name:
- AMBROX DL
- Synonyms
- Cetalox;Ambermor;AMBERLYN;AMBROX DL;Ambraoxide;AMBERLYN 50;Iridium ether;CETALOX 922560;amber naphthofuran;AMBROX DL, FIRMENICH
- CBNumber:
- CB9272233
- Molecular Formula:
- C16H28O
- Molecular Weight:
- 236.39
- MOL File:
- 3738-00-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/25 18:01:23
| Melting point | 75-76 °C |
|---|---|
| Boiling point | 273.9±8.0 °C(Predicted) |
| Density | 0.939±0.06 g/cm3(Predicted) |
| FEMA | 3471 | 1,5,5,9-TETRAMETHYL-13-OXATRICYCLO(8.3.0.0(4,9))TRIDECANE |
| Odor | at 10.00 % in dipropylene glycol. dry woody amber ambergris musk sweet |
| Odor Type | amber |
| JECFA Number | 1240 |
| LogP | 5.41 |
| EPA Substance Registry System | Naphtho[2,1-b]furan, dodecahydro-3a,6,6,9a-tetramethyl- (3738-00-9) |
AMBROX DL Chemical Properties,Uses,Production
Chemical Properties
3a,6,6,9a-Tetramethyldodecahydronaphtho[2,1-b]furan is a crystalline autoxidation product of ambrein with a typical ambergris odor. It is prepared from (?)-sclareol, a diterpene alcohol obtained from extraction of clary sage plants. Oxidative degradation to a lactone (“sclareolide”), hydrogenation of the latter to the corresponding diol, and dehydration yield the title compound.
Occurrence
Reported found in clary sage oil.
Preparation
Racemic sclareolide can be prepared by cyclization of homofarnesic acid in the presence of SnCl4 as a catalyst . Pure diastereomers are obtained by acid cyclization of (E)- and (Z)-4-methyl-6-(2,6,6-trimethylcyclohex-l(2)-enyl)-3- hexen-1-ol, prepared from 2-methyl-4-(2,6,6-trimethylcyclohex-l(2)-enyl)-2- butenal [394]. If the racemic sclareolide mixture is resolved into its enantiomers, the (–)-oxide may also be obtained by a totally synthetic route
Trade name
Compound starting from natural sclareol: Ambermore, Ambermore-DL, Ambermore-EX (Aromor), Ambrox® Super (Firmenich), Ambroxan® (Kao), Ambroxide (Symrise); compound starting from homofarnesic acid derivatives: Ambrox® DL (Firmenich); compound starting from 2-methyl- 4-(2,6,6-trimethylcyclohex-l(2)enyl)-2-butenal: Cetalox® (Firmenich), Cetalor (Aromor).
AMBROX DL Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Ramsun Bio Organics | +91-9742930655 +91-9742475780 | Karnataka, India | 42 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21667 | 55 | Inquiry |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | China | 5873 | 58 | Inquiry |
| Alfa Chemistry | United States | 24072 | 58 | Inquiry | |
| Watson Biotechnology Co.,Ltd | +86-18186686046 +86-18186686046 | China | 5852 | 58 | Inquiry |
| Wuhan Rongcan Biotechnology Co., Ltd | 18327024450 | China | 4575 | 58 | Inquiry |
| BOC Sciences | 1-631-485-4226; 16314854226 | United States | 14059 | 65 | Inquiry |
| Hubei Soren Technology Co., Ltd | 0-13419562052 13419562052 | China | 2552 | 58 | Inquiry |
| Wuhan Xinyang Ruihe Chemical Technology Co., Ltd. | 13720181483 13720181483 | China | 5001 | 58 | Inquiry |
| Service Chemical Inc. | 888-895-6920 | Germany | 6373 | 71 | Inquiry |