Ambroxane
![Ambroxane Structure](CAS/GIF/6790-58-5.gif)
- CAS No.
- 6790-58-5
- Chemical Name:
- Ambroxane
- Synonyms
- AMBROXAN;Ambrox;AMBROFIX;(-)-ambroxide;(?)-Ambroxide;(-)-AMBROXIDE;FEMA 3471;Amberoxan;Naphtho2,1-bfuran, dodecahydro-3a,6,6,9a-tetramethyl-, (3aR,5aS,9aS,9bR)-;Ambropur
- CBNumber:
- CB4423607
- Molecular Formula:
- C16H28O
- Molecular Weight:
- 236.39
- MOL File:
- 6790-58-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/19 22:55:17
Melting point | 74-76 °C (lit.) |
---|---|
alpha | -30 º (c=1% in toluene) |
Boiling point | 273.9±8.0 °C(Predicted) |
Density | 0.939 |
vapor pressure | 0.066Pa at 25℃ |
FEMA | 3471 | 1,5,5,9-TETRAMETHYL-13-OXATRICYCLO(8.3.0.0(4,9))TRIDECANE |
storage temp. | Sealed in dry,Room Temperature |
form | powder to crystaline |
color | White to Almost white |
Odor | at 1.00 % in dipropylene glycol. ambergris old paper sweet labdanum dry |
Odor Type | amber |
optical activity | [α]20/D 29°, c = 1 in toluene |
Water Solubility | 1.88mg/L at 20℃ |
JECFA Number | 1240 |
InChIKey | YPZUZOLGGMJZJO-LQKXBSAESA-N |
LogP | 5.09 at 25℃ |
CAS DataBase Reference | 6790-58-5(CAS DataBase Reference) |
NIST Chemistry Reference | 8 «alpha»,12-epoxy-13,14,15,16-tertanorlabdane(6790-58-5) |
EPA Substance Registry System | Naphtho[2,1-b]furan, dodecahydro-3a,6,6,9a-tetramethyl-, (3aR,5aS,9aS,9bR)- (6790-58-5) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
WGK Germany | 1 |
HS Code | 2932.99.9090 |
Ambroxane price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemicals (India) | A2472 | (-)-Ambroxide min. 98.0 % | 6790-58-5 | 5G | ₹6800 | 2022-05-26 | Buy |
TCI Chemicals (India) | A2472 | (-)-Ambroxide min. 98.0 % | 6790-58-5 | 25G | ₹9900 | 2022-05-26 | Buy |
ottokemi | A 2377 | Ambroxide, 99% | 6790-58-5 | 1gm | ₹2439 | 2022-05-26 | Buy |
ottokemi | A 2377 | Ambroxide, 99% | 6790-58-5 | 5gm | ₹6219 | 2022-05-26 | Buy |
Ambroxane Chemical Properties,Uses,Production
Description
Ambroxan is a synthetic spice with the special aroma of natural ambergris, and it is recognized as one of the best substitutes for natural ambergris. It is one of the most critical trace components of natural ambergris tincture. Natural ambergris is a precious animal spice. It is a kind of stone in the stomach of sperm whale. It is vomited or excreted on the sea surface by the whale, and it emits a special fragrance in the air for a long time.
Uses
(-)-Ambroxide can be used:
To prepare (+)-sclareolide through C-H oxidation strategy.
As a substrate in C(sp3)-H alkylation/arylation studies of ethers.
As a substrate in the study of ethereal hydrocarbon hydroperoxidation using singlet O2.
Definition
ChEBI: Ambroxan is a diterpenoid derived from sclareol that is responsible for the odour of ambergris (a solid, waxy, flammable substance produced in the digestive system of sperm whales). It is an organic heterotricyclic compound and a diterpenoid.
Preparation
Ambroxene naturally occurring autoxidation or photooxide of the triterpenoid secreted by sperm whales.
Industrially, High acacia acid was prepared from nerolidol. After acid internal esterification, the racemic Ambroxene was obtained.
Ambroxide is synthesized from sclareol, a component of the essential oil of clary sage. Sclareol is oxidatively degraded to a lactone, which is hydrogenated to the corresponding diol. The resulting compound is dehydrated to form ambroxide.
Origin
Ambroxane was first synthesized in the 1950s by the Swiss chemical company Firmenich, and it has since become one of the most widely used aroma compounds in the fragrance industry.
General Description
Ambroxide is a terpenoid, which has vast applications in the perfume industry due to its fixative property and odor. Ambergris, which was originally sourced from sperm whale, has been substituted by synthetic ambroxides.
Side effects
The most common side effects associated with Ambroxane use include those which are observed among patients developing allergic reactions. These include pruritus, hives, and swelling in the face, lips, tongue, or throat. It is important to immediately seek medical attention upon the development of dangerous adverse allergic reactions like difficulty in breathing, shortness of breath, convulsions, and mood changes.
Advantages
One of the key advantages of ambroxan is its stability. Unlike some natural aroma compounds, ambroxan is relatively resistant to oxidation and degradation, which means that it can help to extend the lifespan of a fragrance. It is also very versatile and can be used in a wide range of fragrance types, from fresh and light scents to heavier, more complex fragrances. In addition to its use in perfumes and fragrances, ambroxan is also sometimes used in other products such as detergents, soaps, and other personal care products.
Ambroxane Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Akshaya Laboratories Pvt. Ltd | -64642624 | Hyderabad, India | 125 | 58 | Inquiry |
Organica Aromatics Private Limited | +91 80 28361947 | Bangalore, India | 10 | 58 | Inquiry |
Indras Agencies | 91-44-24998804 | Tamil Nadu, India | 18 | 58 | Inquiry |
Dharani Export-Import Services (P) Ltd. | 91-461-2330856 | Tamil Nadu, India | 171 | 58 | Inquiry |
Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
Druja Chem Private Limited | 91-22-40435757 | Maharashtra, India | 17 | 58 | Inquiry |
Raj Aromatics | 91-33-22423606 | Kolkata, India | 31 | 58 | Inquiry |
Karnataka Aromas | 08068970631Ext 815 | Karnataka, India | 104 | 58 | Inquiry |
Arpan Aromatics | 08048372666Ext 828 | Ahmedabad, India | 138 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Akshaya Laboratories Pvt. Ltd | 58 |
Organica Aromatics Private Limited | 58 |
Indras Agencies | 58 |
Dharani Export-Import Services (P) Ltd. | 58 |
Clearsynth Labs | 58 |
Druja Chem Private Limited | 58 |
Raj Aromatics | 58 |
Karnataka Aromas | 58 |
Arpan Aromatics | 58 |
A.J Chemicals | 58 |
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