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ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate Structure
CAS No.
1187479-72-6
Chemical Name:
(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate
Synonyms
Bortezomib Impurity 53;(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate;tert-butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)-benzoyl)piperazin-1-carboxylate;Carbamic acid, N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-, 1,1-dimethylethyl ester
CBNumber:
CB92735156
Molecular Formula:
C29H45BN2O5
Molecular Weight:
512.49
MOL File:
1187479-72-6.mol
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(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate Properties

Boiling point 635.7±55.0 °C(Predicted)
Density 1.10±0.1 g/cm3(Predicted)
pka 11.39±0.46(Predicted)

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate Chemical Properties,Uses,Production

Uses

N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-Carbamic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of bortezomib (B675700).Bortezomib is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate Preparation Products And Raw materials

Raw materials

Preparation Products

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate Suppliers

Global( 11)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Molcoo Chemicals Inc. 17386083646 China 9243 58 Inquiry
Shanghai Zerui Biotechnology Co., Ltd. 021-54580889 18321124657 China 10614 58 Inquiry
Hubei Ruinuo Pharmaceutical Technology Co., Ltd 13165688766 China 5000 58 Inquiry
Hubei Moco Chemical Co., Ltd. 18576690171 China 10974 58 Inquiry
Energy Chemical 021-58432009 400-005-6266 China 44843 58 Inquiry
Shenzhen ruikai de biotechnology co., ltd. 0755-61348847 17820674378 China 7844 58 Inquiry
Chengdu Bochen Chuangke Biomedical Technology Co., Ltd. 13550099873 China 125 58 Inquiry
Supplier Advantage
SynZeal Research Pvt Ltd 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Molcoo Chemicals Inc. 58
Shanghai Zerui Biotechnology Co., Ltd. 58
Hubei Ruinuo Pharmaceutical Technology Co., Ltd 58
Hubei Moco Chemical Co., Ltd. 58
Energy Chemical 58
Shenzhen ruikai de biotechnology co., ltd. 58
Chengdu Bochen Chuangke Biomedical Technology Co., Ltd. 58

1187479-72-6((1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate)Related Search:

Isovaleraldehyde Bortezomib Impurity 8 4,6-Methano-1,3,2-benzodioxaborole,2-[(1S)-1-chloro-3-Methylbutyl]hexahydro-3a,5,5-triMethyl-,(3aS,4S,6S,7aR)- Bortezomib Impurity 57 (R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acid
BORTEZOMIB-PINANEDIOL Bortezomib intermediates II 3,6-Dibenzylhexahydropyrazine-2,5-dione Bortezomib Impurity 52 Bortezomib Impurity 9
Desisobutyl-n-butyl BortezoMib (IS,2S,3R,5S)-Pinanediol-L-phenylalanine-L-leucine boronate, HCl salt (S,E)-N-(1-((3-methylbut-1-en-1-yl)amino)-1-oxo-3-phenylpropan-2-yl) pyrazine-2-carboxamide Bortezomib Impurity 32 (S)-(+)-PINANEDIOL (DICHLORMETHYL)BORONATE
Bortezomib Impurity 47 HCl Bortezomib Impurity 60 4,6-Methano-1,3,2-benzodioxaborole-2-methanamine
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(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate tert-butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)-benzoyl)piperazin-1-carboxylate Bortezomib Impurity 53 Carbamic acid, N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-, 1,1-dimethylethyl ester 1187479-72-6