ChemicalBook > Product Catalog >Organic Chemistry >Amides >Acyclic polyamines and their derivatives >(R)-2-Methyl-pyrrolidine

(R)-2-Methyl-pyrrolidine

(R)-2-Methyl-pyrrolidine Structure
CAS No.
41720-98-3
Chemical Name:
(R)-2-Methyl-pyrrolidine
Synonyms
(2R)-2-Methylpyrrolidine;C-3166R;Methylpyrrolidine hcl;D-2-METHYLPYRROLIDINE;METHYLPYRROLIDINE(S-2-);2-(R)-Methylpyrrolidine;(R)-2-METHYL-PYRROLIDINE;(2R)-2-Methylpyrrolidine hcl;Pyrrolidine, 2-methyl-, (2R)-;(2R)-2-Methylpyrrolidinehydrochloride
CBNumber:
CB9343250
Molecular Formula:
C5H11N
Molecular Weight:
85.15
MOL File:
41720-98-3.mol
Modify Date:
2023/5/31 14:48:13

(R)-2-Methyl-pyrrolidine Properties

Boiling point 94 °C(Press: 728 Torr)
Density 0.842
refractive index 1.4353
Flash point 45 ºF
storage temp. 2-8°C
form oil
pka 10.93±0.10(Predicted)
color Colourless to pale yellow
Water Solubility Insoluble in water.
CAS DataBase Reference 41720-98-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS05,GHS07
Signal word  Danger
Hazard statements  H225-H302-H314
Precautionary statements  P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338
Hazard Codes  C,F
Risk Statements  11-22-34
Safety Statements  26-36/37/39-45
RIDADR  UN 2924
WGK Germany  3
Hazard Note  Corrosive/Highly Flammable
HazardClass  3
PackingGroup 
HS Code  29339900
NFPA 704
3
3 0

(R)-2-Methyl-pyrrolidine price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 679097 (R)-(−)-2-Methylpyrrolidine 41720-98-3 1G ₹12686.9 2022-06-14 Buy
Product number Packaging Price Buy
679097 1G ₹12686.9 Buy

(R)-2-Methyl-pyrrolidine Chemical Properties,Uses,Production

Uses

It is used as a building block used in a multikilogram synthesis of a chiral naphthalenoid histamine receptor antagonist.

Application

(R)-2-Methyl-pyrrolidine, an optically active amine that can be used as a key building block to synthesize:
4,5-fused pyridazinone derivatives are applicable as potent histamine H3 receptor antagonists.
Naphthalenoid histamine H3 receptor antagonist.
Pyrrolo[2,3-d]pyrimidine derivatives as potent inhibitors of leucine-rich repeat kinase 2.

References

Synthesis and structure-activity relationships of 4,5-fused pyridazinones as histamine H3 receptor antagonists. DOI:10.1016/j.bmcl.2011.08.045
Efficient and Practical Synthesis of (R)-2-Methylpyrrolidine DOI:10.1021/jo060319n
Synthesis of (R)-2-Methylpyrrolidine

(R)-2-Methyl-pyrrolidine Preparation Products And Raw materials

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METHYLPYRROLIDINE(S-2-) D-2-METHYLPYRROLIDINE (R)-2-METHYL-PYRROLIDINE (2R)-2-Methylpyrrolidinehydrochloride (2R)-2-Methylpyrrolidine hcl C-3166R 2-(R)-Methylpyrrolidine Methylpyrrolidine hcl Pyrrolidine, 2-methyl-, (2R)- (R)-2-Methyl-pyrrolidine ISO 9001:2015 REACH (2R)-2-Methylpyrrolidine 41720-98-3 Pyrrolidines Heterocyclic Building Blocks Chiral Building Blocks Asymmetric Synthesis Heterocyclic Building Blocks Pyrrolidines Chiral Compound Chiral Building Blocks Benzenes Heterocyclic Series