Protopine
- CAS No.
- 130-86-9
- Chemical Name:
- Protopine
- Synonyms
- BIFLORIN;Protopin;PROTOPINE;Biflorine;Corydinine;Tangeratin;Hypercorine;AKOS 243-72;Corydalis C;Protopine USP/EP/BP
- CBNumber:
- CB9347526
- Molecular Formula:
- C20H19NO5
- Molecular Weight:
- 353.37
- MOL File:
- 130-86-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/7/12 16:34:12
Melting point | 203-205?C |
---|---|
Boiling point | 486.8°C (rough estimate) |
Density | 1.399 (calc) |
refractive index | 1.5800 (estimate) |
storage temp. | Inert atmosphere,2-8°C |
Water Solubility | Insoluble in water |
solubility | DMSO : 12.5 mg/mL (35.37 mM; Need ultrasonic) |
pka | 7.86±0.20(Predicted) |
form | powder to crystal |
color | White to Light gray to Light yellow |
LogP | 3.760 (est) |
NIST Chemistry Reference | Protopine(130-86-9) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P264-P270-P301+P312+P330-P501 | |||||||||
Safety Statements | 24/25 | |||||||||
RIDADR | 1544 | |||||||||
RTECS | VS2800000 | |||||||||
HazardClass | 6.1(b) | |||||||||
PackingGroup | III | |||||||||
HS Code | 29391900 | |||||||||
Toxicity | guinea pig,LD50,intraperitoneal,116mg/kg (116mg/kg),Therapie. Vol. 28, Pg. 767, 1973. | |||||||||
NFPA 704 |
|
Protopine price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemicals (India) | P2611 | Protopine min. 98.0 % | 130-86-9 | 5MG | ₹4400 | 2022-05-26 | Buy |
TCI Chemicals (India) | P2611 | Protopine min. 98.0 % | 130-86-9 | 25MG | ₹8800 | 2022-05-26 | Buy |
TCI Chemicals (India) | P2611 | Protopine min. 98.0 % | 130-86-9 | 100MG | ₹19800 | 2022-05-26 | Buy |
Protopine Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
Protopine is a Ca2+ channel blocker and antiplatelet agent. Immunomodulator
Definition
ChEBI: A dibenzazecine alkaloid isolated from Fumaria vaillantii.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Purification Methods
It crystallises from EtOH/CHCl3. The picrate has m ~240o(dec). [Beilstein 27 H 558, 17 I 568, 17 II 620, 17 III/IV 6881.]
Protopine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 189)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | China | 2931 | 58 | Inquiry |
Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860 +86-18080483897 | China | 3424 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | China | 11667 | 58 | Inquiry |
Apeloa Pharmaceutical Co., Ltd. | +86-0571-87635730 +8615858229168 | China | 1478 | 58 | Inquiry |
130-86-9(Protopine)Related Search:
chevron_left
1of4
chevron_right
7,13a-Secoberbin-13a-one, 7-methyl-2,3:9,10-bis(methylenedioxy)-
7-Methyl-6,8,9,16-tetrahydrodi[1,3]benzodioxolo[4,5-c:5,6-g]azecin-15(7H)-one
Biflorine
Bis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-
Corydinine
Hypercorine
Protopin
BIFLORIN
AKOS 243-72
5,7-DIHYDROXY-2-METHYLCHROMONE-6-C-BETA-D-GLUCOPYRANOSIDE
PROTOPINE
4,6,7,14-Tetrahydro-5-methyl-bis[1,3]benzodioxolo[4,5-c-5',6'-g] azecin-13(5H)-one
7-Methyl-2,3:9,10-bis(methylenedioxy)-7,13a-secoberbin-13a-one
5-Methyl-9,10-(methylenedioxy)-4,6,7,13-tetrahydrobenzo[e]-1,3-dioxolo[4,5-l][2]benzazecine-12(5H)-one
6-Methyl-3,4-(methylenebisoxy)-10,11-(methylenebisoxy)-5,6,7,8-tetrahydrodibenzo[c,g]azecine-13(14H)-one
7-Methyl-6,7,8,9-tetrahydro-[1,3]dioxolo[4',5':5,6]benzo[1,2-c][1,3]dioxolo[5',4':4,5]benzo[1,2-g]azecin-15(16H)-one
4,6,7,14-Tetrahydro-5-Methyl-
Tangeratin
Corydalis C
Protopine (Corydinine)
Protopine, 98%, from Corydalis yanhusuo W. T. Wang ex Z. Y. Su et C. Y. Wu
Protopine USP/EP/BP
1H-Isoindole-1,3(2H)-dione,2-(3-butyn-2-yl)-
130-86-9
C20H19O5
chemical reagent
pharmaceutical intermediate
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract
Aromatics
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals