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4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID

4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID Structure
CAS No.
39793-31-2
Chemical Name:
4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID
Synonyms
DAO-IN-2;79793-31-2;AKOS BB-9991;CHEMBRDG-BB 4012315;D-Amino Acid Oxidase Inhibitor;Thieno[2,3-b]pyrrole-5-carboxylic acid;4-Thieno[3,2-b]pyrrole-5-carboxylic acid;4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID;4H-thieno[2,3-d]pyrrole-5-carboxylic acid;4H-thieno[3,2-b]pyrrole-5-carboxylic acid(SALTDATA: FREE)
CBNumber:
CB9349944
Molecular Formula:
C7H5NO2S
Molecular Weight:
167.19
MOL File:
39793-31-2.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:42
Request For Quotation

4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID Properties

Melting point 180 °C
Boiling point 437.4±25.0 °C(Predicted)
Density 1.609
storage temp. Sealed in dry,2-8°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 2 mg/ml
form Beige solid
pka 4.36±0.30(Predicted)
color Light brown to gray

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  22-26-36/37/39
WGK Germany  3
NFPA 704
1
2 0

4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 760250 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 97% 39793-31-2 500MG ₹6657.38 2022-06-14 Buy
Sigma-Aldrich 138000 D-Amino Acid Oxidase Inhibitor - CAS 39793-31-2 - Calbiochem The D-Amino Acid Oxidase Inhibitor, also referenced under CAS 39793-31-2, controls the biological activity of D-Amino Acid Oxidase. 39793-31-2 50MG ₹7070 2022-06-14 Buy
Sigma-Aldrich(India) 138000 D-Amino Acid Oxidase Inhibitor - CAS 39793-31-2 - Calbiochem The D-Amino Acid Oxidase Inhibitor, also referenced under CAS 39793-31-2, controls the biological activity of D-Amino Acid Oxidase. 39793-31-2 50MG ₹7070 2022-06-14 Buy
Product number Packaging Price Buy
760250 500MG ₹6657.38 Buy
138000 50MG ₹7070 Buy
138000 50MG ₹7070 Buy

4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID Chemical Properties,Uses,Production

Synthesis Reference(s)

Journal of the American Chemical Society, 79, p. 2556, 1957 DOI: 10.1021/ja01567a053

General Description

A cell-permeable thienopyrrole compound that potently inhibits the cellular activity of transfected D-amino acid oxidase (DAO/DAAO/DAMOX/OXDA) in CHO cells (IC50 against human and rat DAO = 145 and 114 nM, respectively), while exhibiting no activity towards D-aspartate oxidase (DDO; IC50 >5 μM), P450 enzymes CYP3A4/2D6/3C9 (IC50 >10 μM), and a panel of over 150 other enzymes, receptors, and ion channels. Although in vivo treatment of Compound 8 (200 mg/kg, i.p.) is shown to effectively inhibit DAO activity in rat brain and kidney (by 96% and 80%, respectively), the resulting D-serine concentration increase in the periphery and central nervous system appears to be far from sufficient to produce adequate antipsychotic and cognitive enhancing effects.

4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID Suppliers

Global( 81)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Coresyn Pharmatech Co., Ltd. +86-571-86626709 +86-18157142896 China 9991 58 Inquiry
Golden Pharma Co., Limited +undefined18958062155 China 5905 58 Inquiry
Hebei Guanlang Biotechnology Co., Ltd. +86-19930503259 +86-19930503259 China 18435 58 Inquiry
SUZHOU SENFEIDA CHEMICAL CO.,LTD +86-0512-83500002 +8615195660023 China 23053 58 Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd +86-0533-2185556 +8617865335152 China 10978 58 Inquiry
Supplier Advantage
A.J Chemicals 58
Capot Chemical Co.,Ltd. 60
career henan chemical co 58
Chongqing Chemdad Co., Ltd 58
CONIER CHEM AND PHARMA LIMITED 58
Coresyn Pharmatech Co., Ltd. 58
Golden Pharma Co., Limited 58
Hebei Guanlang Biotechnology Co., Ltd. 58
SUZHOU SENFEIDA CHEMICAL CO.,LTD 58
Zibo Hangyu Biotechnology Development Co., Ltd 58

39793-31-2(4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID)Related Search:

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Ethyl 4H-thieno[2,3-d]pyrrole-5-carboxylate 3-BROMO-4(H)-THIENO[3,2-B]PYRROLE-5-CARBOXYLICACID 6H-THIENO[2,3-B]PYRROLE-5-CARBOXYLIC ACID ETHYL ESTER METHYL 2-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLATE ETHYL 2-CHLORO-4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLATE
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4H-thieno[3,2-b]pyrrole-5-carboxylic acid(SALTDATA: FREE) Thieno[2,3-b]pyrrole-5-carboxylic acid 4H-thieno[2,3-d]pyrrole-5-carboxylic acid D-Amino Acid Oxidase Inhibitor 4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID AKOS BB-9991 CHEMBRDG-BB 4012315 D-Amino Acid Oxidase Inhibitor - CAS 39793-31-2 - Calbiochem 79793-31-2 4-Thieno[3,2-b]pyrrole-5-carboxylic acid 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid (6CI, 7CI, 9CI, ACI) DAO-IN-2 39793-31-2 79793-31-2 C7H5NO2S