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4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID

4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID Structure
  • ₹6657.38 - ₹7070
  • Product name: 4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID
  • CAS: 39793-31-2
  • MF: C7H5NO2S
  • MW: 167.19
  • EINECS:
  • MDL Number:MFCD07368542
  • Synonyms:4H-thieno[3,2-b]pyrrole-5-carboxylic acid(SALTDATA: FREE);Thieno[2,3-b]pyrrole-5-carboxylic acid;4H-thieno[2,3-d]pyrrole-5-carboxylic acid;D-Amino Acid Oxidase Inhibitor;4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID;AKOS BB-9991;CHEMBRDG-BB 4012315;D-Amino Acid Oxidase Inhibitor - CAS 39793-31-2 - Calbiochem
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • Sigma-Aldrich
  • Sigma-Aldrich(India)

Package

  • 50MG
  • 500MG
  • ManufacturerSigma-Aldrich
  • Product number138000
  • Product descriptionD-Amino Acid Oxidase Inhibitor - CAS 39793-31-2 - Calbiochem The D-Amino Acid Oxidase Inhibitor, also referenced under CAS 39793-31-2, controls the biological activity of D-Amino Acid Oxidase.
  • Packaging50MG
  • Price₹7070
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number760250
  • Product description4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 97%
  • Packaging500MG
  • Price₹6657.38
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number138000
  • Product descriptionD-Amino Acid Oxidase Inhibitor - CAS 39793-31-2 - Calbiochem The D-Amino Acid Oxidase Inhibitor, also referenced under CAS 39793-31-2, controls the biological activity of D-Amino Acid Oxidase.
  • Packaging50MG
  • Price₹7070
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 138000 D-Amino Acid Oxidase Inhibitor - CAS 39793-31-2 - Calbiochem The D-Amino Acid Oxidase Inhibitor, also referenced under CAS 39793-31-2, controls the biological activity of D-Amino Acid Oxidase. 50MG ₹7070 2022-06-14 Buy
Sigma-Aldrich(India) 760250 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 97% 500MG ₹6657.38 2022-06-14 Buy
Sigma-Aldrich(India) 138000 D-Amino Acid Oxidase Inhibitor - CAS 39793-31-2 - Calbiochem The D-Amino Acid Oxidase Inhibitor, also referenced under CAS 39793-31-2, controls the biological activity of D-Amino Acid Oxidase. 50MG ₹7070 2022-06-14 Buy

Properties

Melting point :180 °C
Boiling point :437.4±25.0 °C(Predicted)
Density :1.609
storage temp. :Sealed in dry,2-8°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 2 mg/ml
form :Beige solid
pka :4.36±0.30(Predicted)
color :Light brown to gray

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

D-Amino Acid Oxidase Inhibitor is a cell-permeable thienopyrrole compound that potently inhibits cellular activity of transfected D-amino acid oxidase (DAO/DAAO/DAMOX/OXDA) in CHO cells (IC50 against human and rat DAO = 145 and 114 nM, respectively). Exhibits no activity towards D-aspartate oxidase (DDO; IC50 >5 M), P450 enzymes CYP3A4/2D6/3C9 (IC50 >10 M), and a panel of over 150 other enzymes, receptors, and ion channels. Although treatment of Compound 8 (200 mg/kg, i.p.) is shown to effectively inhibit DAO activity in rat brain and kidney (by 96% and 80%, respectively), the resulting D-serine concentration increase in the periphery and central nervous system appears to be far from sufficient to produce adequate antipsychotic and cognitive enhancing effects.

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Suppliers and manufacturers

career henan chemical co
4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID
₹1.00 /1kg
4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID CAS:39793-31-2
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