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SR-95531

SR-95531 Structure
CAS No.
104104-50-9
Chemical Name:
SR-95531
Synonyms
GABAZINE;SR-95531;GABAZINE BROMIDE;SR 95531 hydrobromid;SR 95531 HYDROBROMIDE;Gabazine Hydrobromide;SR 95531 hydrobromide NEW;Gabazine bromide (SR95531);4-[6-imino-3-(4-methoxyphenyl)pyridazin-1-yl]butanoic acid;2-(3-CARBOXYPROPYL)-3-AMINO-6-(4-METHOXYPHENYL)PYRIDAZINIUM
CBNumber:
CB9356638
Molecular Formula:
C15H18BrN3O3
Molecular Weight:
368.23
MOL File:
104104-50-9.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

SR-95531 Properties

Melting point 200 °C(Solv: ethanol (64-17-5))
storage temp. Store at RT
solubility DMSO: 30 mg/mL
form solid
color white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P305+P351+P338
WGK Germany  3

SR-95531 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S106 SR-95531 ≥98% (HPLC), powder 104104-50-9 10MG ₹18640.65 2022-06-14 Buy
Sigma-Aldrich(India) S106 SR-95531 ≥98% (HPLC), powder 104104-50-9 50MG ₹62503.55 2022-06-14 Buy
Sigma-Aldrich(India) 5.05986 SR95531 (Gabazine) - CAS 104104-50-9 - Calbiochem 104104-50-9 10MG ₹14100 2022-06-14 Buy
Product number Packaging Price Buy
S106 10MG ₹18640.65 Buy
S106 50MG ₹62503.55 Buy
5.05986 10MG ₹14100 Buy

SR-95531 Chemical Properties,Uses,Production

Description

SR 95531 is a derivative of γ-aminobutyric acid (GABA) that acts as an antagonist of GABAA receptors (Ki = 74-150 nM). When administered intravenously, it elicits seizures in mice. SR 95531 differs in action from bicuculline in that it antagonizes GABA-induced chloride currents but not those induced by pentobarbitone. It is effective against GABAA receptor isoforms from mice, rats, and humans.

Uses

Gabazine Hydrobromide is a specific GABA receptor antagonist. Does not affect GABA-transaminase or glutamate-decarboxylase activitites.

Biological Activity

Selective, competitive GABA A receptor antagonist. Displaces [ 3 H]-GABA from rat brain membranes with a K i of 150 nM. Unlike bicuculline, selectively antagonizes GABA-induced Cl - currents with little action on pentobarbitone-induced currents. Also acts as a low affinity glycine receptor antagonist.

SR-95531 Preparation Products And Raw materials

Raw materials

Preparation Products

SR-95531 Suppliers

Global( 89)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
Hunan Jibang Biological Technology Co., LTD +8613776644403 China 1806 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Wuhan Jingkang en Biomedical Technology Co., Ltd +8613720134139 China 4692 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Pharma Affiliates 58
ATK CHEMICAL COMPANY LIMITED 60
Hunan Jibang Biological Technology Co., LTD 58
Nantong HI-FUTURE Biology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Aladdin Scientific 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 58
Amadis Chemical Company Limited 58

104104-50-9(SR-95531)Related Search:

SR 3677 dihydrochloride N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxin-2-carboxamide SR 35021 SR-95531,SR 95531 HYDROBROMIDE,SR-95531 SPECIFIC GABA-A ANTAG,SR-95531,2-(3-Carboxypropyl)-3-amino-6-(4-methoxyphenyl)pyridazinium SR-95531
SR95531, [BUTYRYL-2,3-3H]-
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Gabazine, 2-(3-Carboxypropyl)-3-amino-6-(4 methoxyphenyl)pyridazinium bromide 1(6H)-Pyridazinebutanoic acid, 6-imino-3-(4-methoxyphenyl)-, monohydrobromide 6-Amino-5-methyl-3-(4-methoxyphenyl)-1-pyridaziniumbutyric acid br 6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid monohydrobromide Gabazine Hydrobromide 4-(6-Imino-3-(4-methoxyphenyl)pyridazin-1(6H)-yl)butanoic acid hydrobromide GABAZINE BROMIDE 2-(3-CARBOXYPROPYL)-3-AMINO-6-(4-METHOXYPHENYL)PYRIDAZINIUM 2-(3-CARBOXYPROPYL)-3-AMINO-6-(4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE 6-IMINO-3-(4-METHOXYPHENYL)-1(6H)-PYRIDAZINEBUTANOIC ACID HYDROBROMIDE SR 95531 HYDROBROMIDE SR-95531 SR 95531 hydrobromide NEW SR 95531 hydrobromid Gabazine bromide (SR95531) 4-[6-imino-3-(4-methoxyphenyl)pyridazin-1-yl]butanoic acid GABAZINE Inhibitor,Gamma-aminobutyric acid Receptor,Gabazine,γ-Aminobutyric acid Receptor,inhibit,SR 95531,GABA Receptor,SR-95531 104104-50-9 104105-50-9 C15H17N3O3HBr C15H18BrN3O3 C15H18N3O3Br Cell Biology Cell Signaling and Neuroscience BioChemical Ion Channels Ligand-Gated Ion Channels GABA and Glycine Receptor Modulators GABA/Glycine receptor