(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Structure
CAS No.
59474-01-0
Chemical Name:
(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE
Synonyms
XI-011;NSC 146109;NSC 146109 HYDROCHLORIDE;NSC 146109 (HYDROCHLORIDE);XI-011;XI-011 (NSC 146109 hydrochloride);S-(10-Methylanthracen-9-yl)methyl Isothiourea Hydrochloride;(10-Methylanthracen-9-yl)methyl Carbamimidothiote Hydrochloride;(10-Methylanthracen-9-yl)methyl carbamimidothioate hydrochloride;(10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride;(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE
CBNumber:
CB9385498
Molecular Formula:
C17H17ClN2S
Molecular Weight:
316.85
MOL File:
59474-01-0.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:42

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Properties

storage temp. Desiccate at RT
solubility Soluble to 10 mM in ethanol and to 100 mM in DMSO
form Powder
color White to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H351
Precautionary statements  P201-P202-P264-P270-P280-P301+P312-P330-P308+P313-P405-P501
NFPA 704
0
2 0

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML2570 NSC 146109 hydrochloride ≥98% (HPLC) 59474-01-0 5MG ₹6873.88 2022-06-14 Buy
Sigma-Aldrich(India) SML2570 NSC 146109 hydrochloride ≥98% (HPLC) 59474-01-0 25MG ₹27798.6 2022-06-14 Buy
Product number Packaging Price Buy
SML2570 5MG ₹6873.88 Buy
SML2570 25MG ₹27798.6 Buy

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

This molecule inhibits MDMX expression in breast cancer cells through activating p53 resulting in apoptosis in cancer cells.

Biological Activity

Cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription. Increases levels of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Displays some selectivity for tumor cells vs. normal cells in an MTT cell viability assay.

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Suppliers

Global( 50)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd +86-18341751992 +86-15382112998 China 892 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Wuhan Jingkang en Biomedical Technology Co., Ltd +8613720134139 China 4692 58 Inquiry
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 17316404525 China 9627 58 Inquiry
InvivoChem 13549236410 China 6749 58 Inquiry
ShangHai ChuanQian Chemcial Technique Centre 15869524721 China 3617 58 Inquiry

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Spectrum

NSC 146109 HYDROCHLORIDE (10-Methylanthracen-9-yl)methyl Carbamimidothiote Hydrochloride (10-Methylanthracen-9-yl)methyl carbamimidothioate hydrochloride (10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE (10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride NSC 146109 NSC 146109 (HYDROCHLORIDE);XI-011 XI-011 S-(10-Methylanthracen-9-yl)methyl Isothiourea Hydrochloride XI-011 (NSC 146109 hydrochloride) NSC-146109,proapoptotic,breast cancer,NSC 146109 hydrochloride,inhibit,MDM-2/p53,NSC146109,NSC 146109,p53,Inhibitor,Apoptosis 59474-01-0 C17H16N2SHCl Caspases/Apoptosis Cell Cycle Regulation